Patents by Inventor Denghui Chen

Denghui Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted bridged diazepane derivatives and use thereof as TASK-1 and TASK-3 inhibitors
    Patent number: 11208422
    Abstract: The present application relates to novel imidazopyridinyl- or imidazopyrimidinyl-substituted, bridged 1,4-diazepane derivatives of formula (I), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring. Formula (I) in which the ring Q represents a bridged 1,4-diazepane cycle.
    Type: Grant
    Filed: June 7, 2018
    Date of Patent: December 28, 2021
    Assignees: Bayer Pharma Aktiengesellschaft, Bayer Aktiengesellschaft
    Inventors: Martina Delbeck, Michael Hahn, Thomas Müller, Klemens Lustig, Johanna Anlahr, Karl Collins, Janine Nicolai, Moritz Beck-Broichsitter, Udo Albus, Doris Gehring, Björn Rosenstein, Hongkai Dang, Dehe Duan, Jianfei Yang, Denghui Chen
  • SUBSTITUTED BRIDGED DIAZEPANE DERIVATIVES AND USE THEREOF AS TASK-1 AND TASK-3 INHIBITORS
    Publication number: 20200140461
    Abstract: The present application relates to novel imidazopyridinyl- or imidazopyrimidinyl-substituted, bridged 1,4-diazepane derivatives of formula (I), to processes for their preparation, to their use alone or in combinations for the treatment and/or prevention of diseases, and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for treatment and/or prevention of respiratory disorders including, sleep-related respiratory disorders such as obstructive sleep apnoeas and central sleep apnoeas and snoring.
    Type: Application
    Filed: June 7, 2018
    Publication date: May 7, 2020
    Applicants: Bayer Pharma Aktiengesellschaft, Bayer Aktiengesellschaft
    Inventors: Martina DELBECK, Michael HAHN, Thomas MÜLLER, Klemens LUSTIG, Johanna ANLAHR, Karl COLLINS, Janine NICOLAI, Moritz BECK-BROICHSITTER, Udo ALBUS, Doris GEHRING, Björn ROSENSTEIN, Hongkai DANG, Dehe DUAN, Jianfei YANG, Denghui CHEN
  • Prophy angle device and method of use
    Patent number: 10092382
    Abstract: A disposable prophy angle is provided, the prophy angle comprising a housing containing a drive shaft and a driven shaft; the drive shaft having a proximal end and a distal end and a longitudinal axis therebetween, the distal end having a substantially conical driving portion and a projection, the proximal end of the drive shaft configured to engage a dental hand piece; and the driven shaft having a driven portion comprising a recess configured for engagement by the projection and/or the substantially conical portion of the drive shaft to oscillate the driven shaft at an oscillation angle greater than 90 degrees. In some embodiments, there is a method of making a disposable prophy angle by overmolding a prophy cup to the prophy angle. In other embodiments, there is a method of using the prophy angle to prevent tooth decay.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: October 9, 2018
    Assignees: Crosstex International, Inc., Pac-Dent International, Inc.
    Inventors: Daniel Wang, Denghui Chen, Bo Tao, Bo Yue, Yong Zhu
  • PROPHY ANGLE DEVICE AND METHOD OF USE
    Publication number: 20170202652
    Abstract: A disposable prophy angle is provided, the prophy angle comprising a housing containing a drive shaft and a driven shaft; the drive shaft having a proximal end and a distal end and a longitudinal axis therebetween, the distal end having a substantially conical driving portion and a projection, the proximal end of the drive shaft configured to engage a dental hand piece; and the driven shaft having a driven portion comprising a recess configured for engagement by the projection and/or the substantially conical portion of the drive shaft to oscillate the driven shaft at an oscillation angle greater than 90 degrees. In some embodiments, there is a method of making a disposable prophy angle by overmolding a prophy cup to the prophy angle. In other embodiments, there is a method of using the prophy angle to prevent tooth decay.
    Type: Application
    Filed: July 24, 2014
    Publication date: July 20, 2017
    Applicants: CROSSTEX INTERNATIONAL, INC., PAC-DENT INTERNATIONAL, INC.
    Inventors: Daniel Wang, Denghui Chen, Bo Tao, Bo Yue, Yong Zhu