Abstract: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.

Abstract: A mechanized toilet seat and lid has a pair of quadrant shaped housings fitted, one on each side, to the toilet bowl with each housing containing a moveable lever which is directly connected to the separate hinge shafts of the toilet seat and lid. The levers which are used to lift or lower the toilet seat and lid are moved within the housings by inflation of a pair of pleated rubber bags, one of which is used for lifting and the other for returning the seat and lid to the rest position on the toilet bowl. Wooden or plastic seats can be used with the system and the lever movement of the mechanism can be further employed to operate the flushing mechanism of the cistern and the taps of wash basins. Foot bellows are used to activate the pleated air bags.