Patents by Inventor Denis Bertin

Denis Bertin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10064814
    Abstract: The use of spider venom, molecules or synthetic analogs thereof for skin whitening. Also, compositions that include spider venom, molecules or synthetic analogs thereof for skin whitening/depigmenting, and a non-therapeutic method for whitening human skin that includes topically applying an effective amount on human skin of the composition.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: September 4, 2018
    Assignees: LABORATOIRE IN'OYA, LATOXAN, UNIVERSITE AIX-MARSEILLE
    Inventors: Kamel Mabrouk, Jose Luis, Harold De Pomyers, Denis Bertin, Abd Haq Bengeloune, Marion Verdoni, Didier Gigmes, Hermine Roudaut
  • Patent number: 9474794
    Abstract: The invention relates to antibodies that bind to adrenomedullin and to proteins forming adrenomedullin receptors and to the uses thereof as drugs.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: October 25, 2016
    Assignees: Universite d'Aix-Marseille, Centre National de la Recherche Scientifique
    Inventors: Kamel Mabrouk, L'Houcine Ouafik, Carine Tesic, Denis Bertin, Caroline Berenguer-Daize, Pierre-Marie Martin
  • Patent number: 9458416
    Abstract: It is possible to prevent or at least mitigate discoloration of plastics tableware during machine dishwashing by using amphiphilic block copolymers of -An-Bm- type, where A represents the hydrophilic monomer unit of the hydrophilic block An and B represents the hydrophobic monomer unit of the hydrophobic block Bm and a diene serves as monomer for the hydrophobic monomer unit B.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: October 4, 2016
    Assignee: Henkel AG & Co. KGaA
    Inventors: Benoit Luneau, Christian Kropf, Mareile Job, Nina Mussmann, Thomas Eiting, Konstantin Benda, Thorsten Bastigkeit, Quang Ngoc Tran, Trang Phan, Didier Gigmes, Denis Bertin
  • Patent number: 9431677
    Abstract: The invention relates to a BA diblock or BAB triblock copolymer, in which the A block is a non-substituted poly-oxyethylene chain having a mean molecular weight that is no higher than 100 kDa, and the B block is an anionic polymer which can be prepared using one or more monomers selected from among the vinyl monomers and derivatives thereof, said monomers being substituted with a (trifluoromethylsulfonyl)imide (TFSI) anion. The invention also relates to the uses of such a copolymer, in particular for preparing an electrolyte composition for lithium metal polymer (LMP) batteries.
    Type: Grant
    Filed: September 5, 2012
    Date of Patent: August 30, 2016
    Assignee: UNIVESITE D'AIX-MARSEILLE
    Inventors: Renaud Bouchet, Abdelmaula Aboulaich, Sebastien Maria, Trang Phan, Didier Gigmes, Denis Bertin, Rachid Meziane, Jean-Pierre Bonnet, Michel Armand
  • Patent number: 9422510
    Abstract: The intention was to improve the primary washing power of washing and cleaning agents in particular towards oily and/or greasy soiling This was achieved substantially by incorporating polymers containing styrenesulfonic acid.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: August 23, 2016
    Assignee: Henkel AG & Co. KGaA
    Inventors: Benoit Luneau, Inga Kerstin Vockenroth, Quang Ngoc Tran, Trang Phan, Didier Gigmes, Denis Bertin
  • Publication number: 20150275141
    Abstract: It is possible to prevent or at least mitigate discoloration of plastics tableware during machine dishwashing by using amphiphilic block copolymers of -An-Bm- type, where A represents the hydrophilic monomer unit of the hydrophilic block An and B represents the hydrophobic monomer unit of the hydrophobic block Bm and a diene serves as monomer for the hydrophobic monomer unit B.
    Type: Application
    Filed: May 20, 2015
    Publication date: October 1, 2015
    Inventors: Benoit Luneau, Christian Kropf, Mareile Job, Nina Mussmann, Thomas Eiting, Konstantin Benda, Thorsten Bastigkeit, Quang Ngoc Tran, Trang Phan, Didier Gigmes, Denis Bertin
  • Publication number: 20150252307
    Abstract: The intention was to improve the primary washing power of washing and cleaning agents in particular towards oily and/or greasy soiling This was achieved substantially by incorporating polymers containing styrenesulfonic acid.
    Type: Application
    Filed: May 20, 2015
    Publication date: September 10, 2015
    Inventors: Benoit Luneau, Inga Kerstin Vockenroth, Quang Ngoc Tran, Trang Phan, Didier Gigmes, Denis Bertin
  • Publication number: 20150231061
    Abstract: The use of spider venom, molecules or synthetic analogs thereof for skin whitening. Also, compositions that include spider venom, molecules or synthetic analogs thereof for skin whitening/depigmenting, and a non-therapeutic method for whitening human skin that includes topically applying an effective amount on human skin of the composition.
    Type: Application
    Filed: September 5, 2013
    Publication date: August 20, 2015
    Applicants: LABORATOIRE IN'OYA, LATOXAN, UNIVERSITE AIX, MARSEILLE
    Inventors: Kamel Mabrouk, Jose Luis, Harold De Pomyers, Denis Bertin, Abd Haq Bengeloune, Marion Verdoni, Didier Gigmes, Hermine Roudaut
  • Publication number: 20140308298
    Abstract: The present invention relates to a method for monitoring the tumor growth of an androgen-independent prostate cancer in a subject, by determining the amount of at least one adrenomedullin receptor and optionally adrenomedullin in a prostate cancer cell obtained from said subject. The present invention also relates to a pharmaceutical composition comprising an anti-adrenomedullin antagonist antibody and/or at least one anti-adrenomedullin receptor antagonist antibody for treating an androgen-independent prostate cancer.
    Type: Application
    Filed: November 2, 2012
    Publication date: October 16, 2014
    Applicants: UNIVERSITE D'AIX MARSEILLE, ASSISTANCE PUBLIQUE-HOPITAUX DE MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Institut National de la Sante et de la Recherche
    Inventors: Caroline Berenguer-Daize, Pierre-Marie Martin, Kamel Mabrouk, Denis Bertin, L'Houcine Ouafik
  • Publication number: 20140272600
    Abstract: The invention relates to a BA diblock or BAB triblock copolymer, in which the A block is a non-substituted poly-oxyethylene chain having a mean molecular weight that is higher than 100 kDa and the B block is an anionic polymer which can be prepared using one or more monomers selected from among the vinyl monomers and derivatives thereof, said monomers being substituted with a (trifluoromethylsulfonyl)imide (TFSI) anion. The invention also relates to the uses of such a copolymer, in particular for preparing an electrolyte composition for lithium metal polymer (LMP) batteries.
    Type: Application
    Filed: September 5, 2012
    Publication date: September 18, 2014
    Inventors: Renaud Bouchet, Abdelmaula Aboulaich, Sébastien Maria, Trang Phan, Didier Gigmes, Denis Bertin, Rachid Meziane, Jean-Pierre Bonnet, Michel Armand
  • Publication number: 20140224424
    Abstract: The use of a mixture of 5-pyrimidinol derivatives with sterically hindered phenol derivatives for adjusting the reactivity and the gel time of resin mixtures and reactive resin mortars based on radically polymerizable compounds is described. Furthermore, a resin mixture containing the inhibitor combination, a reactive resin mortar containing this resin mixture and two-component mortar systems with the reactive resin mortar according to the invention and a hardener with improved stability in storage and good low-temperature hardening properties are also described. The resin mixture according to the invention is suitable in particular for chemical fastening of construction elements in boreholes in various substrates.
    Type: Application
    Filed: April 21, 2014
    Publication date: August 14, 2014
    Applicant: Hilti Aktiengesellschaft
    Inventors: Armin PFEIL, Johannes BRINKHORST, Didier GIGMES, Luca VALGIMIGLI, Derek PRATT, Denis BERTIN
  • Patent number: 8735475
    Abstract: The use of a mixture of 5-pyrimidinol derivatives with sterically hindered phenol derivatives for adjusting the reactivity and the gel time of resin mixtures and reactive resin mortars based on radically polymerizable compounds is described. Furthermore, a resin mixture containing the inhibitor combination, a reactive resin mortar containing this resin mixture and two-component mortar systems with the reactive resin mortar according to the invention and a hardener with improved stability in storage and good low-temperature hardening properties are also described. The resin mixture according to the invention is suitable in particular for chemical fastening of construction elements in boreholes in various substrates.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: May 27, 2014
    Assignee: Hilti Aktiengesellschaft
    Inventors: Armin Pfeil, Johannes Brinkhorst, Didier Gigmes, Luca Valgimigli, Derek Pratt, Denis Bertin
  • Publication number: 20130315912
    Abstract: The invention relates to antibodies that bind to adrenomedullin and to proteins forming adrenomedullin receptors and to the uses thereof as drugs.
    Type: Application
    Filed: August 30, 2011
    Publication date: November 28, 2013
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX-MARSEILLE
    Inventors: Kamel Mabrouk, L'Houcine Ouafik, Carine Tesic, Denis Bertin, Caroline Berenguer-Daize, Pierre-Marie Martin
  • Patent number: 8445140
    Abstract: Solid polymer electrolyte (SPE) comprising at least one electrolyte salt and at least one linear triblock copolymer A-B-A, in which: the blocks A are polymers that may be prepared from one or more monomers chosen from styrene, o-methylstyrene, p-methylstyrene, m-t-butoxystyrene, 2,4-dimethylstyrene, m-chlorostyrene, p-chlorostyrene, 4-carboxystyrene, vinylanisole, vinylbenzoic acid, vinylaniline, vinylnaphthalene, 9-vinylanthracene, 1 to 10C alkyl methacrylates, 4-chloromethylstyrene, divinylbenzene, trimethylolpropane triacrylate, tetramethylolpropane tetraacrylate, 1 to 10C alkyl acrylates, acrylic acid and methacrylic acid; the block B is a polymer that may be prepared from one or more monomers chosen from ethylene oxide (EO), propylene oxide (PO), poly(ethylene glycol) acrylates (PEGA) and poly(ethylene glycol) methacrylates (PEGMA). Rechargeable battery cell or accumulator comprising an anode and a cathode between which is intercalated the said solid polymer electrolyte.
    Type: Grant
    Filed: March 30, 2007
    Date of Patent: May 21, 2013
    Assignee: Arkema France
    Inventors: Denis Bertin, Trang Phan, Renaud Bouchet
  • Publication number: 20130123393
    Abstract: The use of a mixture of 5-pyrimidinol derivatives with sterically hindered phenol derivatives for adjusting the reactivity and the gel time of resin mixtures and reactive resin mortars based on radically polymerizable compounds is described. Furthermore, a resin mixture containing the inhibitor combination, a reactive resin mortar containing this resin mixture and two-component mortar systems with the reactive resin mortar according to the invention and a hardener with improved stability in storage and good low-temperature hardening properties are also described. The resin mixture according to the invention is suitable in particular for chemical fastening of construction elements in boreholes in various substrates.
    Type: Application
    Filed: June 8, 2012
    Publication date: May 16, 2013
    Applicant: Hilti Aktiengesellschaft
    Inventors: Armin PFEIL, Johannes BRINKHORST, Didier GIGMES, Luca VALGIMIGLI, Derek PRATT, Denis BERTIN
  • Patent number: 8399561
    Abstract: The present invention relates to a process for preparing a high impact monovinylaromatic polymer comprising admixing a rubber, at least one monovinylaromatic monomer and optionally one or more comonomer in the presence of at least a borane complex of the L-BH3 type wherein L is a Lewis base and polymerizing the monovinylaromatic monomer. The borane complex initiator, L may be an ether (e.g THF, tetrahydrofurane), a thioether (e.g dimethylthioether) or an amine. A preferred complex is an amine borane such as by way of example triethylamine borane. The present invention also relates to a high impact monovinylaromatic polymer having a weight ratio of grafted monovinylaromatic monomer and optional comonomer to the initial monovinylaromatic monomer and optional comonomer above 0.1%, advantageously above 2% and preferably in the range 2 to 4%. The invention is of particular interest to make high impact polystyrene.
    Type: Grant
    Filed: January 21, 2008
    Date of Patent: March 19, 2013
    Assignees: Total Petrochemicals France, Centre National de la Recherche Scientifique
    Inventors: Michel Duc, Bruno Vuillemin, Denis Bertin, Sylvain Marque, Christophe Galindo
  • Patent number: 8013062
    Abstract: The invention relates to the production and use of block copolymers which are obtained by means of controlled radical polymerization in the presence of nitroxides for the purpose of reinforcing fragile polymer matrices. The invention offers advantages such as (i) simplicity of copolymer synthesis and use and (ii) fine dispersion of the copolymer molecules in the fragile matrix, which ensures both the transparency of the material and high reinforcement against impact. More specifically, the invention relates to the radical synthesis of block copolymers comprising at least three blocks, which include one block having a glass transition temperature of less than 0° C. and a thermoplastic end block having a glass transition temperature of more than 0° C., thereby guaranteeing compatibility with the fragile matrix to be reinforced against impact.
    Type: Grant
    Filed: January 21, 2003
    Date of Patent: September 6, 2011
    Assignee: Arkema France
    Inventors: Anne-Valerie Ruzette, Florence Chauvin, Olivier Guerret, Denis Bertin, Bruno Vuillemin, Ludwik Leibler, Pierre Gerard, Yannick Ederle
  • Publication number: 20100240832
    Abstract: The present invention relates to a process for preparing a high impact monovinylaromatic polymer comprising admixing a rubber, at least one monovinylaromatic monomer and optionally one or more comonomer in the presence of at least a borane complex of the L-BH3 type wherein L is a Lewis base and polymerizing the monovinylaromatic monomer. The borane complex initiator, L may be an ether (e.g THF, tetrahydrofurane), a thioether (e.g dimethylthioether) or an amine. A preferred complex is an amine borane such as by way of example triethylamine borane. The present invention also relates to a high impact monovinylaromatic polymer having a weight ratio of grafted monovinylaromatic monomer and optional comonomer to the initial monovinylaromatic monomer and optional comonomer above 0.1%, advantageously above 2% and preferably in the range 2 to 4%. The invention is of particular interest to make high impact polystyrene.
    Type: Application
    Filed: January 21, 2008
    Publication date: September 23, 2010
    Applicant: TOTAL PETROCHEMICALS FRANCE
    Inventors: Michel Duc, Bruno Vuillemin, Denis Bertin, Sylvain Marque, Christophe Galindo
  • Publication number: 20100221614
    Abstract: Solid polymer electrolyte (SPE) comprising at least one electrolyte salt and at least one linear triblock copolymer A-B-A, in which: the blocks A are polymers that may be prepared from one or more monomers chosen from styrene, o-methylstyrene, p-methylstyrene, m-t-butoxystyrene, 2,4-dimethylstyrene, m-chlorostyrene, p-chlorostyrene, 4-carboxystyrene, vinylanisole, vinylbenzoic acid, vinylaniline, vinylnaphthalene, 9-vinylanthracene, 1 to 10C alkyl methacrylates, 4-chloromethylstyrene, divinylbenzene, trimethylolpropane triacrylate, tetramethylolpropane tetraacrylate, 1 to 10C alkyl acrylates, acrylic acid and methacrylic acid; the block B is a polymer that may be prepared from one or more monomers chosen from ethylene oxide (EO), propylene oxide (PO), poly(ethylene glycol) acrylates (PEGA) and poly(ethylene glycol) methacrylates (PELMA). Rechargeable battery cell or accumulator comprising an anode and a cathode between which is intercalated the said solid polymer electrolyte.
    Type: Application
    Filed: March 30, 2007
    Publication date: September 2, 2010
    Inventors: Denis Bertin, Trang Phan, Renaud Bouchet
  • Patent number: 7772340
    Abstract: A subject-matter of the invention is alkoxyamines resulting from ?-phosphorated nitroxides corresponding to the formula: in which R represents an alkyl radical having a number of carbon atoms ranging from 1 to 3, R1 represents a hydrogen atom or a residue: in which R3 represents an alkyl radical having a number of carbon atoms ranging from 1 to 20, and R2 represents a hydrogen atom, an alkyl radical having a number of carbon atoms ranging from 1 to 8, a phenyl radical, an alkali metal, such as Li, Na or K, H4N+, Bu4N+ or Bu3HN+, exhibiting a kinetic dissociation constant kd, measured at 120° C. by EPR, of greater than 0.05 s?1. These compounds can be used as initiators for the (co)polymerizations of at least one monomer which can be polymerized by the radical route.
    Type: Grant
    Filed: July 23, 2003
    Date of Patent: August 10, 2010
    Assignee: Arkema France
    Inventors: Jean-Luc Couturier, Olivier Guerret, Denis Bertin, Didier Gigmes, Sylvain Marque, Paul Tordo, Florence Chauvin, Pierre-Emmanuel Dufils