Patents by Inventor Denis Brasseur

Denis Brasseur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified lipidated Relaxin B chain peptides and their therapeutic use
    Patent number: 10988523
    Abstract: Provided is a biologically active single chain Relaxin peptide having the following formula (I): Nter-Ac-(E)a-X10-E-G-R-E-X15-V-R-X18-X19-I-X21-X22-E-G-X25-S-X27-X28-X29-X30-R-(X32)b-(X33)c-(K)d-(X35)e-(gE)f-X37-Cter; or a salt or solvate thereof. Also provided is a pharmaceutical composition comprising at least one peptide of the invention, and the peptide or the pharmaceutical composition for its use as a medicament.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: April 27, 2021
    Assignee: SANOFI
    Inventors: Denis Brasseur, Olivier Duclos, Stéphane Illiano, Sergio Mallart, Claire Minoletti-Hochepied, Frank Marguet, Elisabetta Bianchi, Raffaele Ingenito, Paola Magotti, Alessia Santoprete
  • MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE
    Publication number: 20190233493
    Abstract: The present invention relates to a biologically active single chain Relaxin peptide having the following formula (I): Nter-Ac-(E)a-X10-E-G-R-E-X15-V-R-X18-X19-I-X21-X22-E-G-X25-S-X27-X28-X29-X30-R-(X32)b-(X33)c-(K)d-(X35)e-(gE)f-X37-Cter; or a salt or solvate thereof. It also concerns a pharmaceutical composition comprising at least one peptide of the invention, and the peptide or the pharmaceutical composition for its use as a medicament.
    Type: Application
    Filed: January 31, 2019
    Publication date: August 1, 2019
    Inventors: Denis Brasseur, Olivier Duclos, Stéphane Illiano, Sergio Mallart, Claire Minoletti-Hochepied, Frank Marguet, Elisabetta Bianchi, Raffaele Ingenito, Paola Magotti, Alessia Santoprete
  • 3-spiroindolin-2-one derivatives, preparation and therapeutic use thereof
    Patent number: 7910584
    Abstract: The subject of the present invention is a compound of formula (I): in the base, hydrate or solvate state, in the form of cis/trans isomers or of mixtures thereof, preparation and therapeutic use thereof.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: March 22, 2011
    Assignee: Sanofi-Aventis
    Inventors: Denis Brasseur, Claudine Serradeil-Le Gal, Gareth Shackleton
  • 3-SPIROINDOLIN-2-ONE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20090275580
    Abstract: The subject of the present invention is a compound of formula (I): in the base, hydrate or solvate state, in the form of cis/trans isomers or of mixtures thereof, preparation and therapeutic use thereof.
    Type: Application
    Filed: July 16, 2009
    Publication date: November 5, 2009
    Applicant: SANOFI-AVENTIS
    Inventors: Denis BRASSEUR, Claudine SERRADEIL-LE GAL, Gareth SHACKLETON
  • 3-SPIROINDOLIN-2-ONE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20090275579
    Abstract: The subject of the present invention is a compound of formula (I): in the base, hydrate or solvate state, in the form of cis/trans isomers or of mixtures thereof, preparation and therapeutic use thereof.
    Type: Application
    Filed: July 16, 2009
    Publication date: November 5, 2009
    Applicant: sanofi-aventis
    Inventors: Denis Brasseur, Claudine Serradeil-Le Gal, Gareth Shackleton
  • 3-SPIROINDOLIN-2-ONE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20070191359
    Abstract: The subject of the present invention is a compound of formula (I): in the base, hydrate or solvate state, in the form of cis/trans isomers or of mixtures thereof, preparation and therapeutic use thereof.
    Type: Application
    Filed: March 7, 2007
    Publication date: August 16, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Denis BRASSEUR, Claudine SERRADEIL-LE GAL, Gareth SHACKLETON
  • 3-SPIROINDOLIN-2-ONE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20070191367
    Abstract: The subject of the present invention is a compound of formula (I): in the base, hydrate or solvate state, in the form of cis/trans isomers or of mixtures thereof, preparation and therapeutic use thereof.
    Type: Application
    Filed: March 7, 2007
    Publication date: August 16, 2007
    Applicant: SANOFI-AVENTIS
    Inventors: Denis BRASSEUR, Claudine SERRADEIL-LE GAL, Gareth SHACKLETON