Patents by Inventor Denis Brillon

Denis Brillon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1-amino thiorcyl benzimidazoyl-2-one compounds
    Patent number: 5371185
    Abstract: This invention relates to 1-amino thioacylbenzimidazoyl-2-one derivatives having the formula: ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are defined herein. These compounds are useful as thioacylating reagents. This invention also relates to a process for producing cyclic and linear thiopeptides using the thioacylating reagents of this invention. This invention further relates to intermediate anilide compounds, which are produced by reacting an ortho phenylene diamine with an amino acid chain or peptide. This invention also relates to intermediate thioanilide compounds, which are produced by thionating the intermediate anilide compounds. This invention further relates to a process for producing the thioacylating reagents of this invention by cyclizing the intermediate thioanilide compounds.
    Type: Grant
    Filed: February 21, 1992
    Date of Patent: December 6, 1994
    Assignee: Biochem Pharma Inc.
    Inventors: Bernard Belleau, Denis Brillon, Gilles Sauve, Boulos Zacharie
  • Thioacylating reagents
    Patent number: 5138061
    Abstract: Thioacylating reagents are provided for the introduction of thioamide bonds into growing peptides represented by the structure: ##STR1## where the substituents are disclosed herein. Intermediate precursors for preparing these thioacylating reagents are also provided. A process for preparing the thioacylating reagents and the intermediate precursors is further provided.
    Type: Grant
    Filed: August 4, 1989
    Date of Patent: August 11, 1992
    Assignee: BioChem Pharma Inc.
    Inventors: Bernard Belleau, deceased, Denis Brillon, Gilles Sauve, Boulos Zacharie