Patents by Inventor Denis Drygin

Denis Drygin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers for predicting the sensitivity and response of protein kinase CK2-mediated diseases to CK2 Inhibitors
    Publication number: 20110212845
    Abstract: Disclosed are biomarkers for determining the sensitivity of protein kinase CK2-mediated diseases, such as proliferative and/or inflammatory disorders, to treatment with CK2 inhibitors. These biomarkers can be used to predict or select subjects likely to be responsive to treatment with a CK2 inhibitor, and to treat or monitor subjects undergoing treatment with a CK2 inhibitor.
    Type: Application
    Filed: October 4, 2010
    Publication date: September 1, 2011
    Inventors: Denis DRYGIN, Sean E. O'BRIEN, Kenna L. ANDERES, Daniel VON HOFF, John K.C. LIM, Claire S. PADGETT, Joshua R. BLIESATH, Caroline B. HO, William G. Rice
  • TREATMENT OF NEOPLASTIC DISORDERS USING COMBINATION THERAPIES
    Publication number: 20100173013
    Abstract: The present application is generally directed to compounds, compositions and methods of combination therapy for the treatment of neoplastic disorders.
    Type: Application
    Filed: January 7, 2010
    Publication date: July 8, 2010
    Inventors: Denis Drygin, Kenna Anderes, Caroline B. Ho, Joshua R. Bliesath, Christopher B. Proffitt, Sean O'Brien, William G. Rice
  • HUMAN RIBOSOMAL DNA (rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF
    Publication number: 20090181377
    Abstract: Provided herein are isolated nucleic acids that comprise a human rRNA or rDNA subsequence and related compositions and methods of use.
    Type: Application
    Filed: February 4, 2008
    Publication date: July 16, 2009
    Applicant: Cylene Pharmaceuticals, Inc.
    Inventors: Denis Drygin, Emil Michelotti, Sean O'Brien, William G. Rice, Adam Siddiqui-Jain, Jeffrey P. Whitten
  • METHODS FOR TREATING ABERRANT CELL PROLIFERATION DISORDERS
    Publication number: 20080318938
    Abstract: The invention relates in part to methods for inhibiting proliferation of cancer cells and treating one or more cell proliferative conditions using compounds described herein.
    Type: Application
    Filed: June 20, 2008
    Publication date: December 25, 2008
    Inventors: David M. RYCKMAN, Denis Drygin, Jeffrey P. Whitten, Kenna Anderes, Katy Trent, Levan Darjania, Mustapha Haddach, Sean O'Brien, William G. Rice
  • Human ribosomal DNA (rDNA) and ribosomal RNA (rRNA) nucleic acids and uses thereof
    Publication number: 20070117770
    Abstract: Provided herein are isolated nucleic acids that comprise a human rRNA or rDNA subsequence and related compositions and methods of use.
    Type: Application
    Filed: August 18, 2006
    Publication date: May 24, 2007
    Applicant: Cylene Pharmaceuticals, Inc.
    Inventors: Denis Drygin, Emil Michelotti, Sean O'Brien, William Rice, Adam Siddiqui-Jain, Jeffrey Whitten