Patents by Inventor Denis Favreau

Denis Favreau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for synthesizing substituted isoquinolines
    Patent number: 8357806
    Abstract: The present disclosure generally relates to a process for synthesizing optionally substituted 1-chloro-4-methoxyisoquinolines. The present disclosure also relates to intermediates useful in this process.
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: January 22, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: Shawn A. Springfield, Wendel W. Doubleday, Frederic Buono, Michel A. Couturier, Yvonne Lear, Denis Favreau, Kathia Levesque, Percy Sarwood Manchand, Markus Frieser, Anthony J. Cocuzza
  • Process for Synthesizing Substituted Isoquinolines
    Publication number: 20120220774
    Abstract: The present disclosure generally relates to a process for synthesizing optionally substituted 1-chloro-4-methoxyisoquinolines. The present disclosure also relates to intermediates useful in this process.
    Type: Application
    Filed: May 10, 2012
    Publication date: August 30, 2012
    Inventors: Shawn A. Springfield, Wendel W. Doubleday, Frederic Buono, Michel A. Couturier, Yvonne Lear, Denis Favreau, Kathia Levesque, Percy Sarwood Manchand, Markus Frieser, Anthony J. Cocuzza
  • Process for Synthesizing Substituted Isoquinolines
    Publication number: 20100056792
    Abstract: The present disclosure generally relates to a process for synthesizing optionally substituted 1-chloro-4-methoxyisoquinolines. The present disclosure also relates to intermediates useful in this process.
    Type: Application
    Filed: August 25, 2009
    Publication date: March 4, 2010
    Inventors: Shawn A. Springfield, Wendel W. Doubleday, Frederic Buono, Michel A. Couturier, Yvonne Lear, Denis Favreau, Kathia Levesque, Percy Sarwood Manchand, Markus Frieser, Anthony J. Cocuzza, Hyungcheol Kim, Sangsoo Lee, Chunyoung Kim, Soonha Yang, Eunhee Choi
  • Polymorphs of an epothilone analog
    Patent number: 7153879
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: December 26, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Polymorphs of an epothilone analog
    Publication number: 20060063815
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Application
    Filed: November 10, 2005
    Publication date: March 23, 2006
    Inventors: John DiMarco, Jack Gougoutas, Imre Vitez, Martha Davidovich, Michael Galella, Timothy Malloy, Zhenrong Guo, Denis Favreau
  • Polymorphs of an epothilone analog
    Patent number: 6982276
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: January 3, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Method of preparation of 21-amino epothilone derivatives
    Patent number: 6930187
    Abstract: An improved method of synthesis of 21-amino epothilone derivatives which provides a one-pot conversion of 21-hydroxy epothilones to highly desirable 21-amino epothilones in high yield.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: August 16, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Denis Favreau, Joydeep Kant, Kathia Levesque, Shaopeng Wang, Zhengrong Guo, Brian Leslie James
  • Polymorphs of an epothilone analog
    Publication number: 20040157897
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula 1
    Type: Application
    Filed: February 6, 2004
    Publication date: August 12, 2004
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Polymorphs of an epothilone analog
    Patent number: 6689802
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula Also provided are methods of forming the novel polymorphs, therapeutic methods utilizing them and pharmaceutical dosage forms containing them.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: February 10, 2004
    Assignee: Bristol-Myers Squibb Company
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Method of preparation of 21-amino epothilone derivatives
    Publication number: 20030187039
    Abstract: An improved method of synthesis of 21-amino epothilone derivatives which provides a one-pot conversion of 21-hydroxy epothilones to highly desirable 21-amino epothilones in high yield.
    Type: Application
    Filed: February 13, 2003
    Publication date: October 2, 2003
    Inventors: Denis Favreau, Joydeep Kant, Kathia Levesque, Shaopeng Wang, Zhengrong Guo, Brian Leslie James
  • Polymorphs of an epothilone analog
    Publication number: 20020188014
    Abstract: There are provided in accordance with the present invention two crystalline polymorphs, designated Form A and Form B, respectively, as well as mixtures thereof, of an epothilone analog represented by the formula 1
    Type: Application
    Filed: August 9, 2001
    Publication date: December 12, 2002
    Inventors: John D. DiMarco, Jack Z. Gougoutas, Imre M. Vitez, Martha Davidovich, Michael A. Galella, Timothy M. Malloy, Zhenrong Guo, Denis Favreau
  • Crystalline etoposide 4'-phosphate diethanolate
    Patent number: 5648474
    Abstract: The present invention provides temperature stable crystalline etoposide 4'-phosphate diethanol solvate, and a process for its preparation.
    Type: Grant
    Filed: October 8, 1991
    Date of Patent: July 15, 1997
    Assignee: Bristol-Myers Squibb
    Inventor: Denis Favreau
  • Process for the preparation of epothilone analogs
    Patent number: RE39356
    Abstract: The present invention relates to a process for the preparation of epothilone analogs by initially forming novel ring-opened epothilones and carrying out a macrolactamization reaction thereon. The subject process is amenable to being carried out in a single reaction vessel without isolation of the intermediate compound and provides at least about a three-fold increase in yield over prior processes for preparing the desired epothilone analogs.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: October 17, 2006
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Wen Sen Li, John E. Thornton, Zhenrong Guo, Shankar Swaminathan, Robert M. Borzilleri, Soong-Hoon Kim, Denis Favreau