Abstract: An aspect of the present disclosure generally relates to a wearable physiological device comprising: (a) a first housing assembly comprising: a first housing body; a first circuit assembly removably coupled to the first housing body; a user interface assembly communicatively connected to the first circuit assembly; and (b) a second housing assembly removably coupled to the first housing assembly, the second housing assembly comprising: a second housing body; a second circuit assembly removably coupled to the second housing body, the second circuit assembly comprising a set of physiological sensors; a removable battery disposed on the second circuit assembly; and a flexible connector communicatively connecting the second circuit assembly to the first circuit assembly, wherein the set of physiological sensors are configured for measuring physiological signals from a user wearing the wearable physiological device, the physiological signals communicable to the user interface assembly.

Abstract: Embodiments relate generally to a sampling device adapted for sampling of biological materials from a subject and methods of use or manufacture of such devices, as well as diagnostic methods employing such devices and kits including such devices. The sampling device may comprise: an outer tube; an elongate insertion member having a first end and a second end, wherein the first end is distal of the second end, the insertion member being received in and sized to be movable through the outer tube; a coupling portion disposed at the first end of the insertion member; and a sampling portion coupled to the coupling portion and configured to collect the biological materials. The coupling portion is separable from the insertion member.