Patents by Inventor Denis Guilloteau

Denis Guilloteau has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RADIOLABELLED COMPOUNDS FOR DIAGNOSING CHOLINERGIC NEURODEGENERATIVE DISEASES
    Publication number: 20240058481
    Abstract: The present invention relates to the radiolabelled compound of enantiomer (R,R) of 5-fluoro-3-4(-phenylpiperidin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol, and to this compound for use thereof in an in vivo diagnosis method, in particular of a cholinergic neurodegenerative disease selected for example from the group formed by Alzheimer's disease, dysmnesia, learning disability, schizophrenia, cognitive dysfunction, hyperactivity disorder, anxiety neurosis, depression, analgesia and Parkinson's disease.
    Type: Application
    Filed: November 23, 2021
    Publication date: February 22, 2024
    Inventors: Sylvain ROUTIER, Frédéric BURON, Franck SUZENET, Nuno RODRIGUES, Sylvie CHALON, Johnny VERCOUILLIE, Denis GUILLOTEAU, Patrick EMOND, Hamid MARZAG
  • Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases
    Patent number: 10906900
    Abstract: The invention relates to compounds of formula (II) for using in imaging and particularly for the diagnosis of neurodegenerative diseases.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: February 2, 2021
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'ORLEANS, UNIVERSITE DE TOURS, CENTRE HOSPITALIER REGIONAL UNIVERSITAIRE DE TOURS, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Sylvain Routier, Franck Suzenet, Sylvie Chalon, Frederic Buron, Johnny Vercouillie, Ronald Melki, Liliana Boiaryna, Denis Guilloteau, Laura Pieri
  • COMPOUNDS FOR USING IN IMAGING AND PARTICULARLY FOR THE DIAGNOSIS OF NEURODEGENERATIVE DISEASES
    Publication number: 20190211011
    Abstract: The invention relates to compounds of formula (II) for using in imaging and particularly for the diagnosis of neurodegenerative diseases
    Type: Application
    Filed: September 26, 2017
    Publication date: July 11, 2019
    Inventors: Sylvain ROUTIER, Franck SUZENET, Sylvie CHALON, Frederic BURON, Johnny VERCOUILLIE, Ronald MELKI, Liliana BOIARYNA, Denis GUILLOTEAU, Laura Ronald PIERI
  • 1,4-disubstituted 1,2,3-triazoles, methods for preparing same, and diagnostic and therapeutic uses thereof
    Patent number: 10059704
    Abstract: A compound having the following general formula (I): wherein: X is a nitrogen atom and Y is a carbon atom; or X is a carbon atom and Y is a nitrogen atom; the Ar group is an aryl or heteroaryl group; and the RN and RN? groups, together with the carbon atoms to which they are bound, form a monocyclic or bicyclic azacycloalkane group. The pharmaceutically acceptable salts thereof, the hydrates or polymorphic crystalline structures thereof, and to the racemates, diastereoisomers, or enantiomers thereof are also described.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: August 28, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.), INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Sylvain Routier, Franck Suzenet, Frederic Pin, Sylvie Chalon, Johnny Vercouillie, Denis Guilloteau
  • 1,4-DISUBSTITUTED 1,2,3-TRIAZOLES, METHODS FOR PREPARING SAME, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF
    Publication number: 20140030191
    Abstract: A compound having the following general formula (I): wherein: X is a nitrogen atom and Y is a carbon atom; or X is a carbon atom and Y is a nitrogen atom; the Ar group is an aryl or heteroaryl group; and the RN and RN? groups, together with the carbon atoms to which they are bound, form a monocyclic or bicyclic azacycloalkane group. The pharmaceutically acceptable salts thereof, the hydrates or polymorphic crystalline structures thereof, and to the racemates, diastereoisomers, or enantiomers thereof are also described.
    Type: Application
    Filed: April 20, 2012
    Publication date: January 30, 2014
    Applicant: Centre National de la Recherche Scientifique (C.N.R.S.)
    Inventors: Sylvain Routier, Franck Suzenet, Frederic Pin, Sylvie Chalon, Johnny Vercouillie, Denis Guilloteau
  • Tropane derivatives useable in particular for in vivo detection of dopamine transporters
    Patent number: 6180083
    Abstract: The present invention relates to tropane derivatives having particular use for the in vivo detection of dopamine transporters. These derivatives meet the formula in which R1 is I or Sn (R3)3, R2 is for example the methyl group, and X and Y are various substituents. The derivatives with X═CH3 and Y═H show strong specificity for the dopamine transporter compared with the serotonin transporter (74% inhibition when the transporter is previously saturated with GBR 12909).
    Type: Grant
    Filed: November 10, 1998
    Date of Patent: January 30, 2001
    Assignee: CIS bio International
    Inventors: Laurent Mauclaire, Patrick Emond, Denis Guilloteau, Jean-Claude Besnard, Yves Frangin