Abstract: Provided herein are analogs of unnatural nucleotides bearing predominantly hydrophobic nucleobase analogs that form unnatural base pairs during DNA polymerase-mediated replication of DNA or RNA polymerase-mediated transcription of RNA. In this manner, the unnatural nucleobases can be introduced in a site-specific way into oligonucleotides (single or double stranded DNA or RNA), where they can provide for site-specific cleavage, or can provide a reactive linker than can undergo functionalization with a cargo-bearing reagent by means of reaction with a primary amino group or by means of click chemistry with an alkyne group of the unnatural nucleobase linker.

Abstract: A method for drilling a subterranean wellbore includes rotating a drill string in the subterranean wellbore to drill the wellbore. The drill string includes a rotary steerable tool or a steerable drill bit including at least first and second axially spaced pads configured to extend radially outward from a tool body and engage a wall of the wellbore. Radial displacements of each of the first and second axially spaced pads are measured while drilling. The measured radial displacements are processed to compute a rate of penetration of drilling.

Abstract: An online meeting system begins the process of connecting a user to an online meeting when a request is received from a user to start or join the online meeting. In response to the request, a pre-meeting user interface (UI) is displayed having a user interface control which, when activated, enables transmission of audio and/or video data for the online meeting, and prior to activation of the control, connection parameters are shared with an online meeting service to preheat the meeting. In response to activation of the control, transmission of audio and/or video data for the online meeting is enabled.

Abstract: A rotary steerable tool may include a tool body with an upper end and a lower end. Additionally, the tool body may include at least one steering assembly extending from the tool body and includes at least one steering actuator configured to extend beyond other portions of the steering assembly. Furthermore, at least one cutter may be disposed on the rotary steerable tool a distance from the at least one steering actuator.

Abstract: A directional drilling assembly includes a downhole piston and an uphole piston. A downhole piston diameter of the downhole piston is smaller than an uphole piston diameter of the uphole piston diameter. This may allow the downhole piston and/or the uphole piston to be located closer to the bit, thereby improving the maximum DLS of the system.

Abstract: A method for drilling a subterranean wellbore includes rotating a drill string in the subterranean wellbore to drill the wellbore. The drill string includes a rotary steerable tool or a steerable drill bit including at least first and second axially spaced pads configured to extend radially outward from a tool body and engage a wall of the wellbore. Radial displacements of each of the first and second axially spaced pads are measured while drilling. The measured radial displacements are processed to compute a rate of penetration of drilling.

Abstract: A method for evaluating a subterranean wellbore includes rotating a drill string in the subterranean wellbore. The drill string includes a rotary steerable tool, a steerable drill bit, or other rotary steering tool with at least one pad configured to extend radially outward from a tool body and engage a wall of the wellbore. Radial displacements of the pad are measured while rotating and processed to compute a curvature of the wellbore.

Abstract: A rotary steerable tool may include a tool body with an upper end and a lower end. Additionally, the tool body may include at least one steering assembly extending from the tool body and includes at least one steering actuator configured to extend beyond other portions of the steering assembly. Furthermore, at least one cutter may be disposed on the rotary steerable tool a distance from the at least one steering actuator.

Abstract: A method for drilling a wellbore through a subterranean formation includes rotating a drill string in the subterranean wellbore to drill. The drill string includes a rotary steerable tool or a steerable drill bit including a plurality of pads configured to extend radially outward from a tool body and engage a wall of the wellbore. Radial displacements of at least one of the pads are measured while rotating (e.g., drilling). A formation index is computed while drilling by processing the measured radial displacements, where the formation index is indicative of a strength or hardness of the subterranean formation.

Abstract: A rotary steerable tool may include a tool body with an upper end and a lower end. Additionally, the tool body may include at least one steering assembly extending from the tool body and includes at least one steering actuator configured to extend beyond other portions of the steering assembly. Furthermore, at least one cutter may be disposed on the rotary steerable tool a distance from the at least one steering actuator.

Abstract: A method for drilling a wellbore through a subterranean formation includes rotating a drill string in the subterranean wellbore to drill. The drill string includes a rotary steerable tool or a steerable drill bit including a plurality of pads configured to extend radially outward from a tool body and engage a wall of the wellbore. Radial displacements of at least one of the pads are measured while rotating (e.g., drilling). A formation index is computed while drilling by processing the measured radial displacements, where the formation index is indicative of a strength or hardness of the subterranean formation.

Abstract: A rotary steerable tool may include a tool body with an upper end and a lower end. Additionally, the tool body may include at least one steering assembly extending from the tool body and includes at least one steering actuator configured to extend beyond other portions of the steering assembly. Furthermore, at least one cutter may be disposed on the rotary steerable tool a distance from the at least one steering actuator.