Patents by Inventor Denis Lucet

Denis Lucet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • In situ or one-pot hydrogenation and reductive amination process
    Patent number: 7462742
    Abstract: An in situ or one-pot process for the preparation of the compounds of formula (I) uses a compound of general formula (I): and includes: a) the hydrogenation of a nitrile group of the compound of general formula (II): in which R1 to R4 are especially H or alkyl and n varies from 0 to 4, in the presence of a hydrogenation catalyst, a methylating agent and an organic acid as solvent, and at a temperature Ta below the initiation temperature of a reductive amination reaction, to give a primary amine from the nitrile group; and b) the reductive amination of the primary amine in the presence of hydrogen, at a temperature Tb above Ta, to give the dimethylated amine of general formula (I) by activation of the methylating age.
    Type: Grant
    Filed: January 23, 2007
    Date of Patent: December 9, 2008
    Assignee: Zach System
    Inventors: Alain Burgos, Jacques Tonnel, Valéry Dambrin, Denis Lucet, Patricia Poirier
  • In situ or one-pot hydrogenation and reductive amination process
    Publication number: 20080125606
    Abstract: An in situ or one-pot process for the preparation of the compounds of formula (I) uses a compound of general formula (I): and includes: a) the hydrogenation of a nitrile group of the compound of general formula (II): in which R1 to R4 are especially H or alkyl and n varies from 0 to 4, in the presence of a hydrogenation catalyst, a methylating agent and an organic acid as solvent, and at a temperature Ta below the initiation temperature of a reductive amination reaction, to give a primary amine from the nitrile group; and b) the reductive amination of the primary amine in the presence of hydrogen, at a temperature Tb above Ta, to give the dimethylated amine of general formula (I) by activation of the methylating age.
    Type: Application
    Filed: January 23, 2007
    Publication date: May 29, 2008
    Applicant: PPG-SIPSY
    Inventors: Alain Burgos, Jacques Tonnel, Valerie Dambrin, Denis Lucet, Patricia Poirier