Patents by Inventor Denis Sereno

Denis Sereno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW COMPOUNDS FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES AND METHOD OF PRODUCTION OF THEREOF
    Publication number: 20190040004
    Abstract: Disclosed are new compounds for treating, preventing or inhibiting a parasitic disease, preferably toxoplasmosis in a subject, the method for preparing thereof.
    Type: Application
    Filed: October 9, 2018
    Publication date: February 7, 2019
    Inventors: Denis SERENO, Gilles LABESSE, Jean-Francois Alexandre GUICHOU, Corinne LOEUILLET, Deborah Isabelle GARCIA, Stephane DELBECQ
  • N-hydroxybenzamides as HDAC inhibitors for the treatment of parasitic diseases
    Patent number: 10106493
    Abstract: Compounds of formula wherein n is 0, 1 or 2; X is and Ar is a benzyl substituted at the meta position by a C1 to C8 alkoxy group, or a pharmaceutically acceptable salt thereof, for treating, preventing or inhibiting a parasitic disease, such as toxoplasmosis, in a subject are provided. Methods for preparing the compounds are also presented.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: October 23, 2018
    Assignees: INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (I.R.D.), UNIVERSITE DE MONTPELLIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Denis Sereno, Gilles Labesse, Jean-Francois Alexandre Guichou, Corinne Loeuillet, Deborah Isabelle Garcia, Stephane Delbecq
  • Analogues of temporin-SHa and uses thereof
    Patent number: 9932376
    Abstract: The present invention relates to novel antimicrobial peptides, pharmaceutical compositions comprising said peptides, and the uses thereof, in particular as antimicrobial drugs, disinfectants, pesticides or preservatives. The present invention also relates to a transgenic plant expressing said novel peptides.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: April 3, 2018
    Assignees: INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: Ali Ladram, Denis Sereno, Thierry Foulon, Bruno Oury
  • Analogs of temporin-SHa and uses thereof
    Patent number: 9522942
    Abstract: The present invention relates to novel antimicrobial peptides, to pharmaceutical compositions comprising said peptides, and to the uses thereof, in particular as antimicrobial drugs, disinfectants, pesticides or preservatives. The present invention also relates to a transgenic plant expressing said novel peptides.
    Type: Grant
    Filed: March 18, 2010
    Date of Patent: December 20, 2016
    Assignees: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), INSTITUT DE RECHERCHE POUR LE DEVELOPMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Ali Ladram, Denis Sereno, Feten Abbassi, Bruno Oury, Mohamed Amiche, Pierre Nicolas
  • ANALOGUES OF TEMPORIN-SHa AND USES THEREOF
    Publication number: 20160280749
    Abstract: The present invention relates to novel antimicrobial peptides, to pharmaceutical compositions comprising said peptides and to the uses thereof, in particular as antimicrobial drugs, disinfectants, pesticides or preservatives. The present invention also relates to a transgenic plant expressing said novel peptides.
    Type: Application
    Filed: September 26, 2014
    Publication date: September 29, 2016
    Inventors: ALI LADRAM, DENIS SERENO, THIERRY FOULON, BRUNO OURY
  • NEW COMPOUNDS FOR THE TREATMENT AND/OR PREVENTION OF PARASITIC DISEASES AND METHOD OF PRODUCTION OF THEREOF
    Publication number: 20160168084
    Abstract: Disclosed are new compounds for treating, preventing or inhibiting a parasitic disease, preferably toxoplasmosis in a subject, the method for preparing thereof.
    Type: Application
    Filed: July 17, 2014
    Publication date: June 16, 2016
    Inventors: Denis SERENO, Gilles LABESSE, Jean-Francois Alexandre GUICHOU, Corinne LOEUILLET, Deborah Isabelle GARCIA, Stephane DELBECQ
  • Method for the screening of conserved secreted proteins
    Patent number: 8865419
    Abstract: Conserved polypeptides from protozoan parasitic species which are secreted through the endoplasmic reticulum/Golgi dependent secretory pathway, their identification and their use.
    Type: Grant
    Filed: July 3, 2009
    Date of Patent: October 21, 2014
    Assignee: Institut de Recherche pour le Developpement (I.R.D.)
    Inventors: Rosa Milagros Corrales, Françoise Mathieu-Daude, Denis Sereno
  • NOVEL AGENTS FOR THE PREVENTION OF LEISHMANIASIS
    Publication number: 20140193452
    Abstract: The invention relates to nucleic acid constructions, characterized in that they comprise nucleic acids which are isolated in the sense position and which are capable of coding for an immunogenic protein of promastigotes or amastigotes of Leishmania, said nucleic acids responding to one of the sequences SEQ ID NO:1, SEQ ID NO:2, SEQ ID NO:3, SEQ ID NO:4, SEQ ID NO:5 et SEQ ID NO:11 and coding for a protein respectively exhibiting a sequence SEQ ID NO:6, SEQ ID NO:7, SEQ ID NO:8, SEQ ID NO:9, SEQ ID NO:10 et SEQ ID NO:12. The invention can be used for over-expression of the genes of Leishmania coding for an excretion/secretion antigen.
    Type: Application
    Filed: November 4, 2013
    Publication date: July 10, 2014
    Inventors: JEAN-LOUP LEMESRE, MIREILLE CAVALEYRA, DENIS SERENO, PHILIPPE HOLZMULLER
  • Agents for the prevention of
    Patent number: 8574598
    Abstract: The invention relates to nucleic acid constructions, characterized in that they comprise nucleic acids which are isolated in the sense position and which are capable of coding for an immunogenic protein of promastigotes or amastigotes of Leishmania, said nucleic acids responding to one of the sequences SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4, SEQ ID No. 5 et SEQ ID No. 11 and coding for a protein respectively exhibiting a sequence SEQ ID No. 6, SEQ ID No. 7, SEQ ID No. 8, SEQ ID No. 9, SEQ ID No. 10 et SEQ ID No. 12. The invention can be used for over-expression of the genes of Leishmania coding for an excretion/secretion antigen.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: November 5, 2013
    Assignee: Institut de Recherche Pour le Developpement (IRD)
    Inventors: Jean-Loup Lemesre, Mireille Cavaleyra, Denis Sereno, Philippe Holzmuller
  • ANALOGS OF TEMPORIN-SHA AND USES THEREOF
    Publication number: 20120005790
    Abstract: The present invention relates to novel antimicrobial peptides, to pharmaceutical compositions comprising said peptides, and to the uses thereof, in particular as antimicrobial drugs, disinfectants, pesticides or preservatives. The present invention also relates to a transgenic plant expressing said novel peptides.
    Type: Application
    Filed: March 18, 2010
    Publication date: January 5, 2012
    Applicants: UNIVERSITE PIERRE ET MARIE CURIE (PARIS VI), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT
    Inventors: Ali Ladram, Denis Sereno, Feten Abassi, Bruno Oury, Mohamed Amiche, Pierre Nicolas
  • METHOD FOR THE SCREENING OF CONSERVED SECRETED PROTEINS
    Publication number: 20110165597
    Abstract: Conserved polypeptides from protozoan parasitic species which are secreted through the endoplasmic reticulum/Golgi dependent secretory pathway, their identification and their use.
    Type: Application
    Filed: July 3, 2009
    Publication date: July 7, 2011
    Applicant: INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (I.R.D.)
    Inventors: Rosa Milagros Corrales, Francoise Mathieu-Daude, Denis Sereno
  • Protozoan strains of reduced virulence and use thereof
    Patent number: 7732188
    Abstract: The present invention relates to a protozoan strain of the family of the Trypanosomatidae the virulence of which is lower than that of the corresponding wild-type strain, characterized in that at least one copy of the SIR2 gene present in the genome of the strain is inactivated.
    Type: Grant
    Filed: October 25, 2004
    Date of Patent: June 8, 2010
    Assignees: Institut de Recherche pour le Developpement, Universidade Do Porto
    Inventors: Anabela Cordeira Da Silva, Ali Ouaissi, Denis Sereno, Baptiste Vergnes
  • Pharmaceutical Compositions For The Treatment Of Leishmaniasis
    Publication number: 20080039430
    Abstract: The present invention relates to the use of at least one compound of the following general formula (I): wherein R represents OH or NH2, or of precursors or derivatives thereof, or of the pharmaceutically acceptable salts of the compound or of its precursors or derivatives, for the manufacture of a medicament intended for the prevention or the treatment of parasitic diseases, in particular of protozoan parasitic diseases, more particularly of leishmaniosis, and especially for the prevention or the treatment of parasitic diseases occurring in immunodepressed patients.
    Type: Application
    Filed: July 15, 2005
    Publication date: February 14, 2008
    Inventors: Ali Ouaissi, Denis Sereno, Baptiste Vergnes
  • Novel Agents for the Prevention of Leishmaniosis
    Publication number: 20080026467
    Abstract: The invention relates to nucleic acid constructions, characterized in that they comprise nucleic acids which are isolated in the sense position and which are capable of coding for an immunogenic protein of promastigotes or amastigotes of Leishmania, said nucleic acids responding to one of the sequences SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3, SEQ ID No. 4, SEQ ID No. 5 et SEQ ID No. 11 and coding for a protein respectively exhibiting a sequence SEQ ID No. 6, SEQ ID No. 7, SEQ ID No. 8, SEQ ID No. 9, SEQ ID No. 10 et SEQ ID No. 12. The invention can be used for over-expression of the genes of Leishmania coding for an excretion/secretion antigen.
    Type: Application
    Filed: November 19, 2004
    Publication date: January 31, 2008
    Inventors: Jean-Loup Lemesre, Mireille Cavaleyra, Denis Sereno, Philippe Holzmuller
  • Protozoan Strains of Reduced Virulence and Use Thereof
    Publication number: 20070224224
    Abstract: The present invention relates to a protozoan strain of the family of the Trypanosomatidae the virulence of which is lower than that of the corresponding wild-type strain, characterized in that at least one copy of the SIR2 gene present in the genome of the strain is inactivated.
    Type: Application
    Filed: October 25, 2004
    Publication date: September 27, 2007
    Inventors: Anabela Cordeira Da Silva, Ali Ouaissi, Denis Sereno, Baptiste Vergnes