Patents by Inventor Denis Severini

Denis Severini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220127283
    Abstract: Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin ? and rifaximin ?, and a poorly crystalline form named rifaximin ?, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
    Type: Application
    Filed: January 6, 2022
    Publication date: April 28, 2022
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20220119410
    Abstract: Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin ? and rifaximin ?, and a poorly crystalline form referred to as rifaximin ?, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a fixed temperature and for a fixed period of time, followed by a drying under controlled conditions until reaching a precise water content in the end product, are the object of the invention.
    Type: Application
    Filed: December 28, 2021
    Publication date: April 21, 2022
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20200339600
    Abstract: Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin ? and rifaximin ?, and a poorly crystalline form referred to as rifaximin ?, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a fixed temperature and for a fixed period of time, followed by a drying under controlled conditions until reaching a precise water content in the end product, are the object of the invention.
    Type: Application
    Filed: July 14, 2020
    Publication date: October 29, 2020
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20200339599
    Abstract: Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin ? and rifaximin ?, and a poorly crystalline form named rifaximin ?, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
    Type: Application
    Filed: July 14, 2020
    Publication date: October 29, 2020
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20190263830
    Abstract: Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin ? and rifaximin ?, and a poorly crystalline form referred to as rifaximin ?, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a fixed temperature and for a fixed period of time, followed by a drying under controlled conditions until reaching a precise water content in the end product, are the object of the invention.
    Type: Application
    Filed: May 10, 2019
    Publication date: August 29, 2019
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20190263829
    Abstract: Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin ? and rifaximin ?, and a poorly crystalline form named rifaximin ?, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
    Type: Application
    Filed: May 10, 2019
    Publication date: August 29, 2019
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20190135831
    Abstract: Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin ? and rifaximin ?, and a poorly crystalline form named rifaximin ?, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
    Type: Application
    Filed: June 7, 2018
    Publication date: May 9, 2019
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20190135830
    Abstract: Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin a and rifaximin 3, and a poorly crystalline form referred to as rifaximin ?, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a fixed temperature and for a fixed period of time, followed by a drying under controlled conditions until reaching a precise water content in the end product, are the object of the invention.
    Type: Application
    Filed: June 7, 2018
    Publication date: May 9, 2019
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20180065987
    Abstract: Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin cc and rifaximin ?, and a poorly crystalline form named rifaximin ?, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
    Type: Application
    Filed: April 13, 2017
    Publication date: March 8, 2018
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20180065988
    Abstract: Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin ? and rifaximin ?, and a poorly crystalline form referred to as rifaximin ?, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a fixed temperature and for a fixed period of time, followed by a drying under controlled conditions until reaching a precise water content in the end product, are the object of the invention.
    Type: Application
    Filed: April 13, 2017
    Publication date: March 8, 2018
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20170210757
    Abstract: Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin ? and rifaximin ?, and a poorly crystalline form referred to as rifaximin ?, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a fixed temperature and for a fixed period of time, followed by a drying under controlled conditions until reaching a precise water content in the end product, are the object of the invention.
    Type: Application
    Filed: September 1, 2016
    Publication date: July 27, 2017
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20170210758
    Abstract: Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin ? and rifaximin ?, and a poorly crystalline form named rifaximin ?, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
    Type: Application
    Filed: September 2, 2016
    Publication date: July 27, 2017
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20150182508
    Abstract: Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin ? and rifaximin ?, and a poorly crystalline form referred to as rifaximin ?, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a fixed temperature and for a fixed period of time, followed by a drying under controlled conditions until reaching a precise water content in the end product, are the object of the invention.
    Type: Application
    Filed: August 12, 2014
    Publication date: July 2, 2015
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis SEVERINI
  • Publication number: 20150175627
    Abstract: Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin ? and rifaximin ?, and a poorly crystalline form named rifaximin ?, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means of a crystallization carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by addition of water at a determinate temperature and for a determinate period of time, followed by a drying carried out under controlled conditions until reaching a settled water content in the end product, are the object of the invention.
    Type: Application
    Filed: August 12, 2014
    Publication date: June 25, 2015
    Inventors: Giuseppe Claudio VISCOMI, Manuela CAMPANA, Dario BRAGA, Donatella CONFORTINI, Vincenzo CANNATA, Paolo RIGHI, Goffredo ROSINI, Denis Severini
  • Patent number: 7045620
    Abstract: Crystalline polymorphous forms of the rifaximin (INN) antibiotic named rifaximin ? and rifaximin ?, and a poorly crystalline form named rifaximin ? have been discovered. These forms are useful in the production of medicinal preparations for oral and topical use and can be obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by the addition of water at a determinate temperature and for a determinate period of time. The crystallization is followed by drying carried out under controlled conditions until a specific water content is reached in the end product.
    Type: Grant
    Filed: December 5, 2003
    Date of Patent: May 16, 2006
    Assignee: Alfa Wassermann, S.p.A.
    Inventors: Giuseppe C. Viscomi, Manuela Campana, Dario Braga, Donatella Confortini, Vincenzo Cannata, Denis Severini, Paolo Righi, Goffredo Rosini
  • Publication number: 20050101598
    Abstract: Crystalline polymorphous forms of the rifaximin (INN) antibiotic named rifaximin ? and rifaximin ?, and a poorly crystalline form named rifaximin ? have been discovered. These forms are useful in the production of medicinal preparations for oral and topical use and can be obtained by means of a crystallization process carried out by hot-dissolving the raw rifaximin in ethyl alcohol and by causing the crystallization of the product by the addition of water at a determinate temperature and for a determinate period of time. The crystallization is followed by drying carried out under controlled conditions until a specific water content is reached in the end product.
    Type: Application
    Filed: December 5, 2003
    Publication date: May 12, 2005
    Applicant: ALFA WASSERMANN S.p.A.
    Inventors: Giuseppe Viscomi, Manuela Campana, Dario Braga, Donatella Confortini, Vincenzo Cannata, Denis Severini, Paolo Righi, Goffredo Rosini