Patents by Inventor Denise KARAOGLU HANZATIAN

Denise KARAOGLU HANZATIAN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LRP-8 binding dual variable domain immunoglobulin proteins
    Patent number: 10093733
    Abstract: The disclosure provides binding proteins that specifically bind to LRP-8 and optionally cross the blood brain barrier (BBB), localize to the brain and/or localize to the spinal cord.
    Type: Grant
    Filed: December 11, 2015
    Date of Patent: October 9, 2018
    Assignee: AbbVie Inc.
    Inventors: Lorenzo Benatuil, Kangwen Deng, Denise Karaoglu Hanzatian, Maria A. Argiriadi
  • LRP-8 Binding Proteins
    Publication number: 20160200813
    Abstract: The disclosure provides binding proteins that specifically bind to LRP-8 and optionally cross the blood brain barrier (BBB), localize to the brain and/or localize to the spinal cord.
    Type: Application
    Filed: December 11, 2015
    Publication date: July 14, 2016
    Inventors: Lorenzo Benatuil, Kangwen Deng, Denise Karaoglu Hanzatian, Maria A. Argiriadi
  • BLOOD-BRAIN BARRIER (BBB) PENETRATING DUAL SPECIFIC BINDING PROTEINS FOR TREATING BRAIN AND NEUROLOGICAL DISEASES
    Publication number: 20160002343
    Abstract: Engineered agents or multivalent and multispecific binding proteins capable of penetrating the cells or tissue of the blood-brain barrier (BBB) are provided, along with methods of making and uses in the prevention, diagnosis, and/or treatment of disease.
    Type: Application
    Filed: June 11, 2015
    Publication date: January 7, 2016
    Inventors: Denise Karaoglu Hanzatian, Andrew D. Goodearl, Bernhard Klaus Mueller, Reinhold Mueller, Corinna Klein
  • BLOOD-BRAIN BARRIER PENETRATING DUAL SPECIFIC BINDING PROTEINS
    Publication number: 20140212423
    Abstract: Engineered multivalent and multispecific binding proteins capable of penetrating the blood-brain barrier (BBB) are provided, along with methods of making and uses in the prevention, diagnosis, and/or treatment of disease.
    Type: Application
    Filed: December 4, 2013
    Publication date: July 31, 2014
    Applicant: ABBVIE, INC.
    Inventors: Denise KARAOGLU HANZATIAN, Tariq GHAYUR, Annette J. SCHWARTZ STERMAN, Andrew GOODEARL, Maria Cristina HARRIS