Patent number: 7141549
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Type:
Grant
Filed:
February 8, 2005
Date of Patent:
November 28, 2006
Inventors:
Peter Mezes, Luca Rastelli, John Herrmann, John MacDougall, Haihong Zhong, Stacie Casman, Ferenc Boldog, Richard Shimkets, Linda Gorman, Andrew Eisen, Steven Spaderna, Corine Vernet, Constance Berghs, Kimberly Spytek, Vincent DiPippo, Bryan Zerhusen, John Peyman, Karen Ellerman, David Stone, William Grosse, John Alsobrook, II, Denise Lepley, Daniel Rieger, Catherine Burgess, Shlomit Edinger, Edward Voss, Charles Miller
Publication number: 20060013813
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Type:
Application
Filed:
February 8, 2005
Publication date:
January 19, 2006
Inventors:
Peter Mezes, Luca Rastelli, John Herrmann, John MacDougall, Haihong Zhong, Stacie Casman, Frenc Boldog, Richard Shimkets, Linda Gorman, Andrew Eisen, Steven Spaderna, Corine Vernet, Constance Berghs, Kimberly Spytek, Vincent DiPippo, Bryan Zerhusen, John Peyman, Karen Ellerman, David Stone, William Grosse, John Alsobrook, Denise Lepley, Daniel Rieger, Catherine Burgess, Sholmit Edinger, Edward Voss, Charles Miller
Publication number: 20060009634
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Type:
Application
Filed:
December 21, 2004
Publication date:
January 12, 2006
Inventors:
Ramesh Kekuda, John Alsobrook, Velizar Tchernev, Xiaohong Liu, Kimberly Spytek, Meera Patturajan, William Grosse, Denise Lepley, Catherine Burgess, Corine Vernet, Li Li, Linda Gorman, Shlomit Edinger, Paul Sciore, Karen Ellerman, Uriel Malyankar, Mark Rothenberg, David Stone, Ferenc Boldog, Xiaojia Guo, Suresh Shenoy, David Anderson, Muralidhara Padigaru, Raymond Taupier, Charles Miller, Andrew Eisen
Publication number: 20040162236
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Type:
Application
Filed:
March 31, 2003
Publication date:
August 19, 2004
Inventors:
John Alsobrook, Patricia Bento, Ferenc Boldog, Catherine Burgess, Stacie Casman, Julie Crabtree Bokor, Shlomit R. Edinger, Karen Ellerman, Elma Fernandes, Valerie Gerlach, William Grosse, Erik Gunther, Vladimir Gusev, Melvyn Heyes, Denise Lepley, Li Li, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Meera Patturajan, John A. Peyman, Luca Rastelli, Daniel Rieger, Suresh Shenoy, Richard Shimkets, Glennda Smithson, David Stone, Corine Vernet, Edward Voss
Publication number: 20040029150
Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
Type:
Application
Filed:
March 31, 2003
Publication date:
February 12, 2004
Inventors:
John Alsobrook, David Anderson, Ferenc Boldog, Catherine Burgess, Stacie Casman, Shlomit R. Edinger, Valerie Gerlach, William Grosse, Xiaojia Guo, Vladimir Gusev, Weizhen Ji, William LaRochelle, Denise Lepley, Li Li, Xiaohong Liu, John R. MacDougall, Uriel M. Malyankar, Isabelle Millet, Muralidhara Padigaru, Meera Patturajan, John A. Peyman, Luca Rastelli, Daniel Rieger, Mark E. Rothenberg, Richard Shimkets, David J. Stone, Raymond Taupier, Corine Vernet, Bryan Zerhusen