Patents by Inventor Denise M. Lepley

Denise M. Lepley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptides of FGF-CX
    Patent number: 7253266
    Abstract: The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: August 7, 2007
    Assignee: CuraGen Corporation
    Inventors: Richard A. Shimkets, Michael Jeffers, Sudhirdas K. Prayaga, Ferenc L. Boldog, Meijia Yang, Catherine Burgess, Elma Fernandes, John L. Herrmann, William J. LaRochelle, Henri Lichenstein, Linda Gorman, Mei Zhong, Muralidhara Padigaru, Carol E. A. Pena, John P. Alsobrook, II, Denise M. Lepley, Daniel K. Rieger, William Grosse
  • Proteins and nucleic acids encoding same
    Patent number: 7109000
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: March 1, 2002
    Date of Patent: September 19, 2006
    Assignee: CuraGen Corporation
    Inventors: Shlomit R. Edinger, John R. MacDougall, Isabelle Millet, Karen Ellerman, David J. Stone, Valerie Gerlach, William M. Grosse, John P. Alsobrook, II, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Stacie J. Casman, Kimberly A. Spytek, Ferenc L. Boldog, Li Li, Muralidhara Padigaru, Vishnu Mishra, Meera Patturajan, Suresh G. Shenoy, Luca Rastelli, Velizar T. Tchernev, Corine A. M. Vernet, Bryan D. Zerhusen, Uriel M. Malyankar, Xiaojia Guo, Charles E. Miller, Esha A. Gangolli
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Patent number: 6974684
    Abstract: Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: December 13, 2005
    Assignee: CuraGen Corporation
    Inventors: David W. Anderson, John P. Alsobrook II, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Shlomit R. Edinger, Esha A. Gangolli, Linda Gorman, Xiaojia Sasha Guo, Nikolai Khramtsov, Denise M. Lepley, John R. MacDougall, Carol E. A. Pena, John A. Peyman, Meera Patturajan, Daniel K. Rieger, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, Corine A. M. Vernet, Edward Z. Voss, Mei Zhong
  • Proteins and nucleic acids encoding same
    Patent number: 6875570
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: April 5, 2005
    Assignee: CuraGen Corporation
    Inventors: Valerie L. Gerlach, John R. MacDougall, Glennda Smithson, Isabelle Millet, David Stone, Erik Gunther, Karen Ellerman, William M. Grosse, John P. Alsobrook, II, Denise M. Lepley, Catherine E. Burgess, Muralidhara Padigaru, Ramesh Kekuda, Kimberly A. Spytek, Martin D. Leach, Richard A. Shimkets
  • Compositions and methods of use for a fibroblast growth factor
    Publication number: 20040214759
    Abstract: In methods of using a fibroblast growth factor, such as for treating, preventing or delaying a proliferation-associated disorder, steps are provided to administer to a subject a therapeutically effective amount of a particular fibroblast growth factor polypeptide, or variant or fragment thereof.
    Type: Application
    Filed: May 9, 2003
    Publication date: October 28, 2004
    Inventors: John P. Alsobrook, Enrique Alvarez, David W. Anderson, Joel S. Bader, Ferenc L. Boldog, Catherine E. Burgess, Rajeev A. Chillakuru, Lisa Deegler, Shlomit R. Edinger, Elma R. Fernandes, Linda Gorman, William M. Grosse, John L. Herrmann, Michael E. Jeffers, William J. LaRochelle, Denise M. Lepley, Henri S. Lichenstein, Kumar Namdev, Muralidhara Padigaru, Carol E. A. Pena, Sudhirdas K. Prayaga, Daniel K. Rieger, Richard A. Shimkets, Pascal Valax, Meijia Yang, Zachary Yim, Mei Zhong
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040096877
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: July 21, 2003
    Publication date: May 20, 2004
    Inventors: Raymond J. Taupier, Muralidhara Padigaru, Luca Rastelli, Steven Kurt Spaderna, Richard A. Shimkets, Bryan D. Zerhusen, Kimberly Ann Spytek, Suresh G. Shenoy, Li Li, Vladimir Y. Gusev, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Valerie L. Gerlach, Karen Ellerman, John R. MacDougall, David J. Stone, Glennda Smithson
  • Novel human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20040068095
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: March 13, 2002
    Publication date: April 8, 2004
    Inventors: Richard A. Shimkets, Raymond J. Taupier, Catherine E. Burgess, Bryan D. Zerhusen, Peter S. Mezes, Luca Rastelli, Uriel M. Malyankar, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Kimberly Ann Spytek, Li Li, Shlomit Edinger, Valerie Gerlach, Karen Ellerman, John R. MacDougall, Erik Gunther, Isabelle Millet, David J. Stone, Glennda Smithson, Edward S. Szekeres, Weizhen Ji
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040067882
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: November 5, 2002
    Publication date: April 8, 2004
    Inventors: John P. Alsobrook, Enrique Alvarez, David W. Anderson, Melanie Baron, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Andrei Chapoval, Mohanraj Dhanabal, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Seth Ettenberg, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, William M. Grosse, Xiaojia (Sasha) Guo, Craig Hackett, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, Denise M. Lepley, Li Li, John R. MacDougall, Uriel M. Malyankar, Ann Mazur, Kelly McQueeney, Peter S. Mezes, Charles E. Miller, Isabelle Millet, Vishnu Mishra, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, John A. Peyman, Luca Rastelli, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Richard A. Shimkets, Glennda Smithson, Steven K. Spaderna, Gary Starling, Kimberly A. Spytek, David J. Stone, Velizar T. Tchernev, Nancy Twomlow, Corine A.M. Vernet, Bryan D. Zerhusen, Edward Z. Voss, Mei Zhong
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040058338
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 2, 2002
    Publication date: March 25, 2004
    Inventors: Michele L. Agee, John P. Alsobrook, David W. Anderson, Constance Berghs, Ferenc L. Boldog, Catherine E. Burgess, Elina Catterton, Vincent A. DiPippo, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Esha A. Gangolli, Valerie Gerlach, Linda Gorman, Bonnie Gould Rothberg, Xiaojia Sasha Guo, John L. Herrmann, Yuan-Di Halvorsen, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, William J. LaRochelle, Denise M. Lepley, Li Li, John R. MacDougall, Charles E. Miller, Tatiana Ort, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, John A. Peyman, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Glennda Smithson, Steven K. Spaderna, Kimberly A. Spytek, David J. Stone, Raymond J. Taupier, Corine A.M. Vernet, Edward Z. Voss, Mei Zhong
  • Proteins and nucleic acids encoding same
    Publication number: 20040052806
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 4, 2002
    Publication date: March 18, 2004
    Inventors: Ramesh Kekuda, John P. Alsobrook, Velizar T. Tchernev, Xiaohong Liu, Kimberly A. Spytek, Meera Patturajan, William M. Grosse, Denise M. Lepley, Catherine E. Burgess, Corine A.M. Vernet, Li Li, Linda Gorman, Shlomit R. Edinger, Paul Sciore, Karen Ellerman, Uriel M. Malyankar, Mark E. Rothenberg, David J. Stone, Ferenc L. Boldog, Xiaojia (Sasha) Guo, Suresh G. Shenoy, David W. Anderson, Muralidhara Padigaru, Raymond J. Taupier, Charles E. Miller, Andrew Eisen
  • Novel human proteins, polynucleotides encoding them and methods of using the same
    Publication number: 20040048245
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: October 5, 2001
    Publication date: March 11, 2004
    Inventors: Richard A. Shimkets, Raymond J. Taupier, Catherine E. Burgess, Bryan D. Zerhusen, Peter S. Mezes, Luca Rastelli, Uriel M. Malyankar, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Kimberly Ann Spytek, Li Li, Shlomit Edinger, Valerie Gerlach, Karen Ellerman, John R. MacDougall, Erik Gunther, Isabelle Millet, David J. Stone, Glennda Smithson, Edward S. Szekeres
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040048256
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 6, 2002
    Publication date: March 11, 2004
    Inventors: Michele L. Agee, John P. Alsobrook, David W. Anderson, Constance Berghs, Ferenc L. Boldog, Catherine E. Burgess, Stacie J. Casman, Elina Catterton, John S. Chant, Amitabha Chaudhuri, Julie Bokor, Vincent A. DiPippo, Shlomit R. Edinger, Andrew Eisen, Karen Ellerman, Esha A. Gangolli, Valerie Gerlach, Loic Giot, Linda Gorman, Xiaojia (Sasha) Guo, Vladimir Y. Gusev, Weizhen Ji, Ramesh Kekuda, Nikolai V. Khramtsov, Martin D. Leach, Denise M. Lepley, Li Li, Xiaohong Liu, Uriel M. Malyankar, Charles E. Miller, Chean Eng Ooi, Tatiana Ort, Muralidhara Padigaru, Meera Patturajan, Carol E. A. Pena, Daniel K. Rieger, Mark E. Rothenberg, Suresh G. Shenoy, Richard A. Shimkets, Steven K. Spaderna, Kimberly A. Spytek, Raymond J. Taupier, Nancy Twomlow, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen, Mei Zhong
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040043926
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: September 26, 2001
    Publication date: March 4, 2004
    Inventors: Valerie L. Gerlach, John R. MacDougall, Glennda Smithson, Isabelle Millet, David Stone, Erik Gunther, Karen Ellerman, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Muralidhara Padigaru, Ramesh Kekuda, Kimberly A. Spytek, Martin D. Leach, Richard A. Shimkets
  • Novel proteins and nucleic acids encoding same
    Publication number: 20040043382
    Abstract: The present invention provides novel isolated polynucleotides and small molecule target polypeptides encoded by the polynucleotides. Antibodies that immunospecifically bind to a novel small molecule target polypeptide or any derivative, variant, mutant or fragment of that polypeptide, polynucleotide or antibody are disclosed, as are methods in which the small molecule target polypeptide, polynucleotide and antibody are utilized in the detection and treatment of a broad range of pathological states. More specifically, the present invention discloses methods of using recombinantly expressed and/or endogenously expressed proteins in various screening procedures for the purpose of identifying therapeutic antibodies and therapeutic small molecules associated with diseases.
    Type: Application
    Filed: March 7, 2002
    Publication date: March 4, 2004
    Inventors: Muralidhara Padigaru, Kimberly A. Spytek, Suresh G. Shenoy, Raymond J. Taupier, Carol E. A. Pena, Li Li, Bryan D. Zerhusen, Vladimir Y. Gusev, Weizhen Ji, Linda Gorman, Charles E. Miller, Ramesh Kekuda, Meera Patturajan, Esha A. Gangolli, Corine A.M. Vernet, Xiaojia Sasha Guo, Velizar T. Tchernev, Elma R. Fernandes, Stacie J. Casman, Uriel M. Malyankar, Valerie Gerlach, Yi Liu, David W. Anderson, Steven K. Spaderna, Elina Catterton, Mario W. Leite, Haihong Zhong, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess
  • Therapeutic polypeptides, nucleic acids encoding same, and methods of use
    Publication number: 20040043928
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies that immunospecifically bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the novel polypeptide, polynucleotide, or antibody specific to the polypeptide. Vectors, host cells, antibodies and recombinant methods for producing the polypeptides and polynucleotides, as well as methods for using same are also included. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: August 1, 2002
    Publication date: March 4, 2004
    Inventors: Ramesh Kekuda, Charles E. Miller, Meera Patturajan, Carol E. A. Pena, Daniel K. Rieger, Richard A. Shimkets, Bryan D. Zerhusen, Li Li, Weizhen Ji, Muralidhara Padigaru, Stacie J. Casman, Edward Z. Voss, Ferenc L. Boldog, Linda Gorman, Mario W. Leite, Corine A.M. Vernet, David W. Anderson, Xiaojia Sasha Guo, Mei Zhong, Valerie Gerlach, Luca Rastelli, Tord Hjalt, Kimberly A. Spytek, Shlomit R. Edinger, Karen Ellerman, Uriel M. Malyankar, John R. MacDougall, David J. Stone, John P. Alsobrook, Denise M. Lepley, Catherine E. Burgess, Kumud Majumder, Adam R. Wolenc, Glennda Smithson, Jason C. Baumgartner
  • Proteins and nucleic acids encoding same
    Publication number: 20040033493
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 31, 2002
    Publication date: February 19, 2004
    Inventors: Velizar T. Tchernev, Kimberly A. Spytek, Bryan D. Zerhusen, Meera Patturajan, Richard A. Shimkets, Li Li, Esha A. Gangolli, Muralidhara Padigaru, David W. Anderson, Luca Rastelli, Charles E. Miller, Valerie Gerlach, Raymond J. Taupier, Vladimir Y. Gusev, Steven D. Colman, Adam Ryan Wolenc, Carol E. A. Pena, Katarzyna Furtak, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess
  • Proteins and nucleic acids encoding same
    Publication number: 20040033491
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: December 10, 2001
    Publication date: February 19, 2004
    Inventors: John P. Alsobrook, David W. Anderson, Catherine E. Burgess, Ferenc L. Boldog, Stacie J. Casman, Steven D. Colman, Shlomit R. Edinger, Karen Ellerman, Valerie Gerlach, Linda Gorman, William M. Grosse, Xiaojia Sasha Guo, John L. Herrmann, Ramesh Kekuda, Denise M. Lepley, Li Li, John R. MacDougall, Isabelle Millet, Carol E. A. Pena, John A. Peyman, Luca Rastelli, Daniel K. Rieger, Richard A. Shimkets, Glennda Smithson, Kimberly A. Spytek, David J. Stone, Velizar T. Tchernev, Corine A.M. Vernet, Edward Z. Voss, Bryan D. Zerhusen, Haihong Zhong, Mei Zhong
  • Proteins and nucleic acids encoding same
    Publication number: 20040029116
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: March 1, 2002
    Publication date: February 12, 2004
    Inventors: Shlomit R. Edinger, John R. MacDougall, Isabelle Millet, Karen Ellerman, David J. Stone, Valerie Gerlach, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Stacie J. Casman, Kimberly A. Spytek, Ferenc L. Boldog, Li Li, Muralidhara Padigaru, Vishnu Mishra, Meera Patturajan, Suresh G. Shenoy, Luca Rastelli, Velizar T. Tchernev, Corine A.M. Vernet, Bryan D. Zerhusen, Uriel M. Malyankar, Xiaojia Guo, Charles E. Miller, Esha A. Gangolli
  • Proteins and nucleic acids encoding same
    Publication number: 20040029222
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: August 14, 2002
    Publication date: February 12, 2004
    Inventors: Shlomit R. Edinger, John R. MacDougall, Isabelle Millet, Karen Ellerman, David J. Stone, Valerie Gerlach, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Danier K. Rieger, Catherine E. Burgess, Stacie J. Casman, Kimberly A. Spytek, Ference L. Boldog, Li Li, Muralidhara Padigaru, Vishnu Mishra, Meera Patturajan, Suresh G. Shenoy, Luca Rastelli, Velizar T. Tchernev, Corine A.M. Vernet, Bryan D. Zerhusen, Uriel M. Malyankar, Xiaojia (Sasha) Guo, Charles E. Miller, Esha A. Gangolli, Michael Grosse
  • Proteins and nucleic acids encoding same
    Publication number: 20040018196
    Abstract: Disclosed herein are nucleic acid sequences that encode novel polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
    Type: Application
    Filed: January 11, 2002
    Publication date: January 29, 2004
    Inventors: Peter D. Mezes, Luca Rastelli, John L. Herrmann, John R. MacDougall, Haihong Zhong, Stacie J. Casman, Ferenc L. Boldog, Richard A. Shimkets, Linda Gorman, Andrew J. Eisen, Steven K. Spaderna, Corine A.M. Vernet, Constance Berghs, Kimberly A. Spytek, Vincent A. DiPippo, Bryan D. Zerhusen, John A. Peyman, Karen Ellerman, David J. Stone, William M. Grosse, John P. Alsobrook, Denise M. Lepley, Daniel K. Rieger, Catherine E. Burgess, Shlomit R. Edinger