Patents by Inventor Denise Ronen

Denise Ronen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Diagnosing and Treating Insulin Resistance
    Publication number: 20110104167
    Abstract: A method of treating insulin resistance in a subject is provided. The method comprising administering to the subject a therapeutically effective amount of an agent capable of down-regulating phosphorylation of an IRS protein at at least one serine residue corresponding to amino acid 341, 412 and/or 413 of human IRS-1, thereby treating the insulin resistance in the subject. Also provided are methods and kits for diagnosing insulin resistance.
    Type: Application
    Filed: October 30, 2005
    Publication date: May 5, 2011
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Yehiel Zick, Yanfang Liu, Denise Ronen
  • Compositions and methods of using galectin-8 as an inhibitor of tumor cell growth
    Patent number: 7416725
    Abstract: The present invention provides compositions that enhance or inhibit the interactions of galectin-8 and galectin-8-like proteins with other extracellular matrix proteins or cell surface receptors, and methods for the use thereof as physiological modulators of cell adhesion and in treatment of tumors, both in vivo or ex vivo. It further provides compositions and methods for modulating the expression of galectin-8, and galectin-8-like proteins, particularly to novel antisense oligonucleotides.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: August 26, 2008
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Yehiel Zick, Yifat Levy, Rinat Arbel-Goren, Denise Ronen, Yaron R. Hadari
  • COMPOSITIONS AND METHODS OF USING GALECTIN-8 AS AN INHIBITOR OF TUMOR CELL GROWTH
    Publication number: 20070160602
    Abstract: The present invention provides compositions that enhance or inhibit the interactions of galectin-8 and galectin-8-like proteins with other extracellular matrix proteins or cell surface receptors, and methods for the use thereof as physiological modulators of cell adhesion and in treatment of tumors, both in vivo or ex vivo. It further provides compositions and methods for modulating the expression of galectin-8, and galectin-8-like proteins, particularly to novel antisense oligonucleotides.
    Type: Application
    Filed: December 19, 2006
    Publication date: July 12, 2007
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Yehiel Zick, Yifat Levy, Rinat Arbel-Goren, Denise Ronen, Yaron Hadari
  • Compositions and methods of using galectin-8 as an inhibitor of tumor cell growth
    Patent number: 7176181
    Abstract: The present invention provides compositions that enhance or inhibit the interactions of galectin-8 and galectin-8-like proteins with other extracellular matrix proteins or cell surface receptors, and methods for the use thereof as physiological modulators of cell adhesion and in treatment of tumors, both in vivo or ex vivo. It further provides compositions and methods for modulating the expression of galectin-8, and galectin-8-like proteins, particularly to novel antisense oligonucleotides.
    Type: Grant
    Filed: May 21, 2002
    Date of Patent: February 13, 2007
    Assignee: Yeda Research and Development Co. Ltd.
    Inventors: Yehiel Zick, Yifat Levy, Rinat Arbel-Goren, Denise Ronen, Yaron R. Hadari
  • Compositions and methods of using galectin-8 as an inhibitor of tumor cell growth
    Publication number: 20030220231
    Abstract: The present invention provides compositions that enhance or inhibit the interactions of galectin-8 and galectin-8-like proteins with other extracellular matrix proteins or cell surface receptors, and methods for the use thereof as physiological modulators of cell adhesion and in treatment of tumors, both in vivo or ex vivo. It further provides compositions and methods for modulating the expression of galectin-8, and galectin-8-like proteins, particularly to novel antisense oligonucleotides.
    Type: Application
    Filed: May 21, 2002
    Publication date: November 27, 2003
    Inventors: Yehiel Zick, Yifat Levy, Rinat Arbel-Goren, Denise Ronen, Yaron R. Hadari