Abstract: Disclosed is a method for producing a porous orodispersible film, having the following steps: i) forming a suspension of a pharmaceutically acceptable solvent, a pharmaceutically acceptable matrix material, and a pharmaceutically acceptable binder, said solvent being selected such that the pharmaceutically acceptable matrix material substantially does not dissolve in it, whereas the pharmaceutically acceptable binder is dissolved in the solvent, ii) casting the suspension onto a neutral support, thereby forming a wet film, and iii) drying the wet film and obtaining a dry film. The films produced in this manner have a closed surface on the lower face whereas the upper face is porous, thereby allowing the application of a pharmaceutically active ingredient in the form of a suspension or a solution for example.

Abstract: A binder insert with a folder portion and a clip. The folder portion defines at least one ring aperture configured and dimensioned to receive and mount to rings of a binder. The folder portion also has a first sheet defining a clip-mounting aperture and a second sheet facing the first sheet. The clip includes first and second clip portions resiliently biased toward each other. The clip is mounted to the first sheet through the clip-mounting aperture, and the first and second clip portions are disposed in a clamping position on the exterior of the first and second sheets and compressively engaged against the sheets to bias them against each other.