Patents by Inventor Denise Van Rossum

Denise Van Rossum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11913949
    Abstract: The present invention relates to a multiparameter lateral flow strip (1), comprising a microporous membrane layer (2) supported on a liquid-impermeable support layer (3), for lateral flow of a liquid through the microporous membrane layer (2), wherein the microporous membrane layer (2) has two or more flow lanes (4) in the direction of lateral flow, wherein said two or more flow lanes (4) are separated by hydrophobic separation channels (5), and wherein each of said two or more flow lanes (4) comprises a detection spot (6) including a binding agent, wherein said two or more flow lanes (4) are isomorphic lanes. Furthermore, the present invention relates to a multiparameter lateral flow immunoassay device comprising said multiparameter lateral flow membrane (1), the use of said multiparameter configured lateral flow membrane (1) in an immunological test, as well as to a method for the manufacture of said multiparameter configured lateral flow membrane (1).
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: February 27, 2024
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Denise Van Rossum, Eric Jallérat, Susanne Drebing, Dieter Melzner
  • Patent number: 11313854
    Abstract: The present invention relates to a patterned membrane structure comprising a microporous membrane layer, wherein the microporous membrane layer includes a plurality of flow lanes, the flow lanes are separated by hydrophobic separation channels, and the flow lanes and hydrophobic separation channels form a repetitive pattern; and a method for manufacture of the patterned membrane structure. The patterned membrane structure according to the present invention represents an industrial scale precursor of membranes such as a multiparameter lateral flow membrane comprising separated flow lanes.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: April 26, 2022
    Inventors: Susanne Drebing, Alfons Kesting, Dieter Melzner, Denise Van Rossum
  • Patent number: 10345314
    Abstract: The present invention relates to a lateral flow membrane arrangement (1), comprising a microporous membrane layer (2) and a liquid-impermeable support layer (3), for lateral flow of a liquid through the microporous membrane layer (2), wherein the microporous membrane layer (2) is supported on the liquid-impermeable support layer (3) and has at least one detection zone (5) and at least one non-detection zone, wherein binding agents are immobilized in the at least one detection zone (5), the liquid-impermeable support layer (3) has at least one zone having a large thickness and at least one zone having a small thickness, the microporous membrane layer (2) is supported on the liquid-impermeable support layer (3) such that said at least one detection zone is provided above said at least one zone of the support layer having a large thickness and said at least one non-detection zone is provided above said at least one zone of the support layer having a small thickness, the zones are oriented in a direction orthogon
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: July 9, 2019
    Assignee: SARTORIUS STEDIM BIOTECH GMBH
    Inventors: Dieter Melzner, Denise Van Rossum
  • Publication number: 20180328918
    Abstract: The present invention relates to a patterned membrane structure comprising a microporous membrane layer, wherein the microporous membrane layer includes a plurality of flow lanes, the flow lanes are separated by hydrophobic separation channels, and the flow lanes and hydrophobic separation channels form a repetitive pattern; and a method for manufacture of the patterned membrane structure. The patterned membrane structure according to the present invention represents an industrial scale precursor of membranes such as a multiparameter lateral flow membrane comprising separated flow lanes.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 15, 2018
    Inventors: Susanne DREBING, Alfons KESTING, Dieter MELZNER, Denise VAN ROSSUM
  • Publication number: 20180143191
    Abstract: The present invention relates to a multiparameter lateral flow strip (1), comprising a microporous membrane layer (2) supported on a liquid-impermeable support layer (3), for lateral flow of a liquid through the microporous membrane layer (2), wherein the microporous membrane layer (2) has two or more flow lanes (4) in the direction of lateral flow, wherein said two or more flow lanes (4) are separated by hydrophobic separation channels (5), and wherein each of said two or more flow lanes (4) comprises a detection spot (6) including a binding agent, wherein said two or more flow lanes (4) are isomorphic lanes. Furthermore, the present invention relates to a multiparameter lateral flow immunoassay device comprising said multiparameter lateral flow membrane (1), the use of said multiparameter configured lateral flow membrane (1) in an immunological test, as well as to a method for the manufacture of said multiparameter configured lateral flow membrane (1).
    Type: Application
    Filed: April 28, 2015
    Publication date: May 24, 2018
    Inventors: Denise Van Rossum, Eric Jallérat, Susanne Drebing, Dieter Melzner
  • Patent number: 9891230
    Abstract: The present invention relates to a microarray device for the screening or the finding of protein inhibitors, to a method for the production thereof, and to a corresponding method for screening or finding protein inhibitors. The microarray device according to the invention comprises a solid supporting element having a support material, at least one protein immobilized thereon for which inhibitors are to be screened or found, and at least one known inhibitor of the at least one protein, the inhibitor being bound to the at least one protein and comprising a detectable label.
    Type: Grant
    Filed: April 20, 2012
    Date of Patent: February 13, 2018
    Assignee: SARTORIUS STEDIM BIOTECH GMBH
    Inventors: Dieter Melzner, Thomas Scheper, Thomas Schueler, Frank Stahl, Denise Van Rossum, Johanna-Gabriela Walter, Carsten Zeilinger
  • Publication number: 20160178640
    Abstract: The present invention relates to a lateral flow membrane arrangement (1), comprising a microporous membrane layer (2) and a liquid-impermeable support layer (3), for lateral flow of a liquid through the microporous membrane layer (2), wherein the microporous membrane layer (2) is supported on the liquid-impermeable support layer (3) and has at least one detection zone (5) and at least one non-detection zone, wherein binding agents are immobilized in the at least one detection zone (5), the liquid-impermeable support layer (3) has at least one zone having a large thickness and at least one zone having a small thickness, the microporous membrane layer (2) is supported on the liquid-impermeable support layer (3) such that said at least one detection zone is provided above said at least one zone of the support layer having a large thickness and said at least one non-detection zone is provided above said at least one zone of the support layer having a small thickness, the zones are oriented in a direction orthogon
    Type: Application
    Filed: April 29, 2014
    Publication date: June 23, 2016
    Inventors: Dieter MELZNER, Denise VAN ROSSUM
  • Publication number: 20140228235
    Abstract: The present invention relates to a microarray device for the screening or the finding of protein inhibitors, to a method for the production thereof, and to a corresponding method for screening or finding protein inhibitors. The microarray device according to the invention comprises a solid supporting element having a support material, at least one protein immobilized thereon for which inhibitors are to be screened or found, and at least one known inhibitor of the at least one protein, the inhibitor being bound to the at least one protein and comprising a detectable label.
    Type: Application
    Filed: April 20, 2012
    Publication date: August 14, 2014
    Inventors: Dieter Melzner, Thomas Scheper, Thomas Schuler, Frank Stahl, Denise Van Rossum, Johanna-Gabriela Walter, Carsten Zeilinger