Patents by Inventor Denise Y. Burton

Denise Y. Burton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090068745
    Abstract: The invention relates to compositions and methods for reverse gene therapy, wherein a gene therapy vector encoding a gene product (e.g. a protein) which is usually only expressed in cells of an abnormal tissue is delivered to a cell of an animal afflicted with a disease or disorder to alleviate the disease or disorder. In one embodiment, a plasmid vector encoding HERG (A561V) protein is delivered to a cell of an animal afflicted with re-entrant atrial flutter-mediated cardiac arrhythmia.
    Type: Application
    Filed: October 15, 2007
    Publication date: March 12, 2009
    Inventors: Robert J. Levy, Denise Y. Burton
  • Patent number: 7282489
    Abstract: The invention relates to compositions and methods for reverse gene therapy, wherein a gene therapy vector encoding a gene product (e.g. a protein) which is usually only expressed in cells of an abnormal tissue is delivered to a cell of an animal afflicted with a disease or disorder to alleviate the disease or disorder. In one embodiment, a plasmid vector encoding HERG (A561V) protein is delivered to a cell of an animal afflicted with re-entrant atrial flutter-mediated cardiac arrhythmia.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: October 16, 2007
    Assignee: The Children's Hospital of Philadelphia
    Inventors: Robert J. Levy, Denise Y. Burton
  • Publication number: 20040087528
    Abstract: The invention relates to compositions and methods for reverse gene therapy, wherein a gene therapy vector encoding a gene product (e.g. a protein) which is usually only expressed in cells of an abnormal tissue is delivered to a cell of an animal afflicted with a disease or disorder to alleviate the disease or disorder. In one embodiment, a plasmid vector encoding HERG (A561V) protein is delivered to a cell of an animal afflicted with re-entrant atrial flutter-mediated cardiac arrhythmia.
    Type: Application
    Filed: July 31, 2003
    Publication date: May 6, 2004
    Inventors: Robert J. Levy, Denise Y. Burton