Patents by Inventor Dennis A. Dougherty

Dennis A. Dougherty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of determining precise HERG interactions and designing compounds based on said interactions
    Publication number: 20040180401
    Abstract: The present invention discloses methods of determining highly precise interactions between the HERG ion channel and various compounds. The methods of the present invention utilize the nonsense codon suppression methods combined with heterologous in vivo expression in Xenopus oocytes.
    Type: Application
    Filed: May 23, 2003
    Publication date: September 16, 2004
    Applicant: Neurion Pharmaceuticals, Inc.
    Inventors: Dennis A. Dougherty, Henry A. Lester, Jonathan G. Lasch
  • High energy polymers formed by ring opening metathesis polymerization
    Patent number: 5026783
    Abstract: A precursor route to the synthesis of polyacetylene and other conductive polymers is provided by the formation of high energy polymers by ring opening metathesis polymerization. In particular, the high energy polymers having the following general formula are formed from monomers as shown: ##STR1## In the formula, A is an organic structure that is relieved of strain upon the ring opening polymerization and B is an organic structure with strain energy.gtoreq.20 kcal/mole. Such high energy polymers are also found to be spontaneously decomposable with heat or mechanical stress. Consequently, the high energy polymers formed in accordance with the invention may find use in explosives or other sources of high energy.
    Type: Grant
    Filed: October 24, 1988
    Date of Patent: June 25, 1991
    Assignee: California Institute of Technology
    Inventors: Robert H. Grubbs, Dennis A. Dougherty, Timothy M. Swager, Eric J. Ginsburg