Patents by Inventor Dennis A. Smith

Dennis A. Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8778967
    Abstract: The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: July 15, 2014
    Assignee: Genzyme Corporation
    Inventors: Gary Bridger, Renato T Skelj, Al Kaller, Curtis Harwig, David Bogucki, Trevor R Wilson, Jason B Crawford, Ernest J McEachern, Bem Atsma, Siqiao Nan, Yuanxi Zhou, Dominique Schols, Christopher Dennis Smith, Maria R Di Fluri
  • Patent number: 8765989
    Abstract: The present invention relates to a process for the preparation of S-[2-[1-(2-ethylbutyl)cyclohexylcarbonylamino]-phenyl]2-methylthiopropionate which is a useful pharmaceutical active compound.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: July 1, 2014
    Assignee: Hoffmann - La Roche Inc.
    Inventors: Declan Costello, Gerard John Hamett, Pirmin Hidber, Ursula Hoffmann, Thomas McCarthy, Reinhard Reents, Dennis A. Smith, Timothy Smyth
  • Publication number: 20140031614
    Abstract: A kit for packing the bowels of a subject. The kit comprises an elastomeric bowel packing device manually positioned within the subject to retain the bowels of the subject in an operational displaced position and to provide a surgical operational space; and an elongate tether having a distal end coupled to the device via an attachment arrangement.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 30, 2014
    Inventors: Steven J. Kubisen, Anthony P. Deasey, Dennis Smith
  • Publication number: 20140024886
    Abstract: An elastomeric device for packing the bowels of a subject comprising: a central portion and one or more flaps collectively manually positionable within the subject to retain the bowels of the subject in an operational, displaced position and to provide a surgical operational space; and a support structure disposed in at least one of the central portion and the flaps configured to provide rigidity to the device.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 23, 2014
    Inventors: Anthony P. Deasey, Steven J. Kubisen, David J. Hicks, Dennis Smith
  • Publication number: 20130338391
    Abstract: The present invention relates to a process for the preparation of S-[2-[1-(2-ethylbutyl)cyclohexylcarbonylamino]-phenyl] 2-methylthiopropionate which is a useful pharmaceutical active compound.
    Type: Application
    Filed: August 22, 2013
    Publication date: December 19, 2013
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Declan Costello, Gerard John Harnett, Pirmin Hidber, Ursula Hoffmann, Thomas McCarthy, Reinhard Reents, Dennis A. Smith, Timothy Smyth
  • Publication number: 20130018201
    Abstract: A process for the preparation of a compound of formula (I): which is useful as an intermediate in the preparation of pharmaceutically active compounds.
    Type: Application
    Filed: July 5, 2012
    Publication date: January 17, 2013
    Inventors: Beat Birrer, Leo Clarke, Walter Deichtmann, John Hayes, Julius Jeisy, Christian Lautz, Rainer E. Martin, Michael Meade, Joaquim Pintao, Michelangelo Scalone, Juergen Schaefer, Dennis Smith, Andreas Staempfli, Joachim Veits, Christian Walch, Andrew Walsh, Andreas Zogg
  • Publication number: 20120303103
    Abstract: A method and apparatus of treating tissue adjacent to a bodily conduit using thermotherapy, while preventing obstructions of the bodily conduit due to edema employs the circulation of warmed fluid to maintain the temperature of the bodily conduit walls and compresses the tissue to be treated to increase the effectiveness of the irradiated heat. An energy-emitting source containing catheter is inserted in a bodily conduit and is positioned in a region of the tissue to be treated so that the energy-emitting source radiates energy to the tissue to be treated. Fluid warmed to over 30° C. is circulated into and through the catheter to warm walls of the bodily conduit adjacent the catheter. The warmed circulated fluid inflates a balloon to a pressure to compress the tissue to form a natural stent that remains after the catheter and compression balloon are removed.
    Type: Application
    Filed: June 14, 2012
    Publication date: November 29, 2012
    Applicant: BOSTON SCIENTIFIC CORPORATION
    Inventors: John Mon, Dennis Smith
  • Patent number: 8290435
    Abstract: A short-range communication system includes an antenna, a transmitter, and a receiver. The antenna is an electrical conductor formed as a planar coil with rings thereof being uniformly spaced. The transmitter is spaced apart from the plane of the coil by a gap. An amplitude-modulated and asynchronous signal indicative of a data stream of known peak amplitude is transmitted into the gap. The receiver detects the coil's resonance and decodes same to recover the data stream.
    Type: Grant
    Filed: September 30, 2008
    Date of Patent: October 16, 2012
    Assignee: The United States of America as Represented by the Administrator of the Administrator of the National Aeronautics and Space Administration
    Inventors: Dean C. Alhorn, David E. Howard, Dennis A. Smith
  • Publication number: 20120228827
    Abstract: An apparatus to track one or more all-in bets in a game with a standard deck of playing cards that includes a set of at least a first marker and a second marker, the first marker of the set of markers to identify an all-in pot a player is playing to win, the second marker of the set of markers to identify the player that is playing to win the all-in pot and at least one additional identifier on the first and second markers of the set to indicate that they are related to each other. There is also a method for tracking an all-in playing card game.
    Type: Application
    Filed: May 28, 2012
    Publication date: September 13, 2012
    Inventor: Dennis Smith
  • Patent number: 8221413
    Abstract: A method and apparatus of treating tissue adjacent to a bodily conduit using thermotherapy, while preventing obstructions of the bodily conduit due to edema employs the circulation of warmed fluid to maintain the temperature of the bodily conduit walls and compresses the tissue to be treated to increase the effectiveness of the irradiated heat. An energy-emitting source containing catheter is inserted in a bodily conduit and is positioned in a region of the tissue to be treated so that the energy-emitting source radiates energy to the tissue to be treated. Fluid warmed to over 30° C. is circulated into and through the catheter to warm walls of the bodily conduit adjacent the catheter. The circulated fluid inflates a balloon to a pressure to compress the tissue to be treated. The combination of warmed fluid over 30° C.
    Type: Grant
    Filed: August 3, 2010
    Date of Patent: July 17, 2012
    Assignee: Boston Scientific Corporation
    Inventors: John Mon, Dennis Smith
  • Publication number: 20120143010
    Abstract: A device for human organ packing in a laproscopic surgical procedure, including an expandable barrier configured to be laproscopically implanted into a human abdominal cavity such that a side of the expandable barrier interfaces with organs in the abdominal cavity, thereby forming a barrier between the organs and a region of the abdominal cavity on an opposing side of the barrier relative to the organs, wherein at least a portion of the barrier is configured to be controllably transformed from a first state to a second state, wherein when in the second state the barrier is in a more rigid state relative to the first state.
    Type: Application
    Filed: November 30, 2011
    Publication date: June 7, 2012
    Inventors: Anthony P. Deasey, Steven J. Kubisen, David J. Hicks, Dennis Smith
  • Publication number: 20120088961
    Abstract: An elastomeric device for packing the bowels of a subject comprising: a central portion and one or more flaps collectively manually positionable within the subject to retain the bowels of the subject in an operational, displaced position and to provide a surgical operational space; and a support structure disposed in at least one of the central portion and the flaps configured to provide rigidity to the device.
    Type: Application
    Filed: June 22, 2011
    Publication date: April 12, 2012
    Inventors: Anthony P. Deasey, Steven J. Kubisen, David J. Hicks, Dennis Smith
  • Publication number: 20120088960
    Abstract: A kit for packing the bowels of a subject. The kit comprises an elastomeric bowel packing device manually positioned within the subject to retain the bowels of the subject in an operational displaced position and to provide a surgical operational space; and an elongate tether having a distal end coupled to the device via an attachment arrangement.
    Type: Application
    Filed: June 22, 2011
    Publication date: April 12, 2012
    Inventors: Steven J. Kubisen, Anthony P. Deasey, Dennis Smith
  • Patent number: 8143442
    Abstract: A process for the preparation of a compound of formula (Ia): which are useful as intermediates in the preparation of i.a. pharmaceutically active compounds.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: March 27, 2012
    Assignee: Hoffmann-LA Roche Inc.
    Inventors: Gerard John Harnett, Ursula Hoffmann, Michael Jansen, Reinhard Reents, Tim Sattelkau, Dennis A. Smith, Helmut Stahr
  • Publication number: 20120071683
    Abstract: A process for the preparation of a compound of formula (I): which is useful as an intermediate in the preparation of pharmaceutically active compounds.
    Type: Application
    Filed: September 14, 2011
    Publication date: March 22, 2012
    Inventors: Gerard John Harnett, John Hayes, Reinhard Reents, Dennis A. Smith, Andrew Walsh
  • Patent number: 8098060
    Abstract: Systems, methods and apparatus are provided through which in some implementations determine the amplitude of an amplitude modulated signal, modulated by the position of an object being sensed. In some aspects, the apparatus accepts an excitation signal and the amplitude modulated signal and divides the amplitude modulated by the excitation signal to produce an output signal that is proportional to the position of the object being sensed. In other aspects, the division is performed only when the excitation signal is non-zero, such as close to the peaks in the excitation signal. In other aspects, the excitation signal and amplitude modulated signal are degraded due to an air gap and the degraded signals are used to correct for amplitude fluctuations due to the air gap, and produce an output signal, tolerant of the air gaps, that is proportional to the position of the object being sensed.
    Type: Grant
    Filed: July 15, 2008
    Date of Patent: January 17, 2012
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: David E. Howard, Dean C. Alhorn, Dennis A. Smith, Kenneth R. Dutton
  • Patent number: 7911174
    Abstract: A method and system are provided for sensing the position of a rotor in a hybrid stepper motor. First and second Hall sensors are positioned in a spaced-apart relationship with the first and second armatures of the rotor such that the first and second Hall sensors generate electrical outputs that are 90° out of phase with one another as the rotor rotates. The electrical outputs are adjusted relative to a reference, and the amplitude of the electrical outputs is further adjusted to account for spacing differences between the rotor and each of the first and second Hall sensors.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: March 22, 2011
    Assignee: The United States of America as represented by the Administrator of the National Aeronautics and Space Administration
    Inventors: David E. Howard, Dean C. Alhorn, Dennis A. Smith
  • Publication number: 20110004011
    Abstract: The present invention relates to a process for the preparation of S-[2-[1-(2-ethylbutyl)cyclohexylcarbonylamino]-phenyl]2-methylthiopropionate which is a useful pharmaceutical active compound.
    Type: Application
    Filed: June 25, 2010
    Publication date: January 6, 2011
    Inventors: Declan Costello, Gerard John Harnett, Pirmin Hidber, Ursula Hoffmann, Thomas McCarthy, Reinhard Reents, Dennis A. Smith, Timothy Smyth
  • Publication number: 20100314587
    Abstract: The disclosure provides compositions prepared by combining nanomaterials with a halide-containing polymer, thereby forming a combined polymer matrix having dispersed nanomaterials within the matrix. The nanomaterials may be carbon-based nanotubes, in some applications. A halide-containing monomer is combined with nanotubes, and then polymerized in some compositions. In other applications, a halide-containing polymer is solution processed with nanotubes to form useful compositions in the invention. Also disclosed are probes for near field detection of radiation.
    Type: Application
    Filed: June 10, 2010
    Publication date: December 16, 2010
    Inventors: David Carroll, John Ballato, Stephen Foulger, Richard Czerw, Dennis Smith, Hiren Shah, Earl Wagener
  • Publication number: 20100298913
    Abstract: A method and apparatus of treating tissue adjacent to a bodily conduit using thermotherapy, while preventing obstructions of the bodily conduit due to edema employs the circulation of warmed fluid to maintain the temperature of the bodily conduit walls and compresses the tissue to be treated to increase the effectiveness of the irradiated heat. An energy-emitting source containing catheter is inserted in a bodily conduit and is positioned in a region of the tissue to be treated so that the energy-emitting source radiates energy to the tissue to be treated. Fluid warmed to over 30° C. is circulated into and through the catheter to warm walls of the bodily conduit adjacent the catheter. The circulated fluid inflates a balloon to a pressure to compress the tissue to be treated. The combination of warmed fluid over 30° C.
    Type: Application
    Filed: August 3, 2010
    Publication date: November 25, 2010
    Applicant: Boston Scientific Corporation
    Inventors: John MON, Dennis SMITH