Patents by Inventor Dennis Andress

Dennis Andress has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for improving lipid profiles using atrasentan
    Patent number: 9855245
    Abstract: The present disclosure is directed to methods for reducing cardiovascular risk in a human subject by administering atrasentan, or a pharmaceutically acceptable salt thereof, in an amount sufficient to effect a reduction of about 5% or more in one or both of (a) total serum cholesterol, relative to the subject's baseline total serum cholesterol, and (b) serum LDL cholesterol, relative to the subject's baseline serum LDL cholesterol.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: January 2, 2018
    Assignee: AbbVie Inc.
    Inventors: Blas Coll Crespo, Dennis Andress, John J. Brennan, James C. Stolzenbach
  • METHODS OF TREATING CKD USING PREDICTORS OF FLUID RETENTION
    Publication number: 20160128980
    Abstract: The disclosure relates to methods of treating chronic kidney disease and diabetic nephropathy using predictors of fluid retention to minimize the risk of adverse events. The methods disclosed are particularly useful in treatments involving endothelin receptor antagonists, and more particularly, atrasentan and pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: November 6, 2015
    Publication date: May 12, 2016
    Inventors: Donald K. Kohan, Hiddo J. Lambers Heerspink, Dick de Zeeuw, Blai Coll, Dennis Andress
  • METHODS FOR IMPROVING LIPID PROFILES USING ATRASENTAN
    Publication number: 20160074363
    Abstract: The present disclosure is directed to methods for reducing cardiovascular risk in a human subject by administering atrasentan, or a pharmaceutically acceptable salt thereof, in an amount sufficient to effect a reduction of about 5% or more in one or both of (a) total serum cholesterol, relative to the subject's baseline total serum cholesterol, and (b) serum LDL cholesterol, relative to the subject's baseline serum LDL cholesterol.
    Type: Application
    Filed: April 30, 2014
    Publication date: March 17, 2016
    Applicant: Abbvie Inc.
    Inventors: Blas COLL CRESPO, Dennis ANDRESS, Peter J. BRENNAN, James C. STOLZENBACH
  • Methods of Treating Acute Kidney Injury
    Publication number: 20160015701
    Abstract: Methods are provided for treating acute kidney injury in a subject, particularly ischemia-induced kidney injury and/or hypoxia-induced kidney injury. The methods comprise administering to the subject an ETA receptor antagonist, such as atrasentan or a pharmaceutically acceptable salt thereof. Methods of diagnosing and treating such kidney injuries are also provided. Methods of reducing or preventing loss of kidney function and/or renal mass or volume, and methods of delaying progression to chronic kidney disease are also provided.
    Type: Application
    Filed: March 10, 2014
    Publication date: January 21, 2016
    Inventors: Richard A. Zager, Dennis Andress