Patents by Inventor Dennis Cvitkovitch

Dennis Cvitkovitch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TREATMENT OF GROUP A STREPTOCOCCI
    Publication number: 20110150916
    Abstract: Immunogenic compositions and vaccines are described comprising GAS Markers including AtmB Proteins. Methods for detecting GAS diseases in a subject are also described comprising measuring GAS markers or antibodies against GAS markers in a sample from the subject. The invention further provides kits for carrying out the methods of the invention and therapeutic applications for GAS diseases employing GAS markers, polynucleotides encoding the markers, and/or binding agents for the markers.
    Type: Application
    Filed: November 15, 2007
    Publication date: June 23, 2011
    Applicant: MOUNT SINAI HOSPITAL
    Inventors: Kowthar Salim, Joyce De Azavedo, Dennis Cvitkovitch
  • THERAPEUTICS AND DIAGNOSTICS FOR GROUP A STREPTOCOCCI
    Publication number: 20100285047
    Abstract: Immunogenic compositions and vaccines are described comprising GAS Markers. Methods for detecting GAS diseases in a subject are also described comprising measuring GAS markers in a sample from the subject. The invention further provides kits for carrying out the methods of the invention and therapeutic applications for GAS diseases employing GAS markers, polynucleotides encoding the markers, and/or binding agents for the markers.
    Type: Application
    Filed: July 3, 2008
    Publication date: November 11, 2010
    Inventors: Kowthar Salim, Joyce De Azavedo, Dennis Cvitkovitch
  • Signal peptides, nucleic acid molecules and methods for treatment of caries
    Patent number: 7556807
    Abstract: Peptide analogues of S. mutans CSP peptide which inhibit biofilm formation, uses thereof in the preparation of pharmaceutical compositions, antimicrobial compositions and uses thereof in the treatment and prevention of infections caused by biofilm forming bacteria, dental plaque formation, and conditions caused by dental plaque associated bacteria are provided.
    Type: Grant
    Filed: July 28, 2005
    Date of Patent: July 7, 2009
    Assignees: Kane Biotech, Inc., The Governing Council of the University of Toronto
    Inventors: Dennis Cvitkovitch, Srinivasa Madhyastha
  • Signal peptides, nucleic acid molecules and methods for treatment of caries
    Publication number: 20060067951
    Abstract: Peptide analogues of S. mutans CSP peptide which inhibit biofilm formation, uses thereof in the preparation of pharmaceutical compositions, antimicrobial compositions and uses thereof in the treatment and prevention of infections caused by biofilm forming bacteria, dental plaque formation, and conditions caused by dental plaque associated bacteria are provided.
    Type: Application
    Filed: July 28, 2005
    Publication date: March 30, 2006
    Inventors: Dennis Cvitkovitch, Srinivasa Madhyastha
  • Signal peptides, nucleic acid molecules and methods for treatment of caries
    Patent number: 6923962
    Abstract: The invention relates to a compound that competitively inhibits binding of CSP to S. mutans histidine kinase. The compound is preferably a peptide or an antibody. The compound is preferably a derivative of [SEQ ID NO:2], a fragment of [SEQ ID NO:2] or a derivative of a fragment of [SEQ ID NO:2].
    Type: Grant
    Filed: April 10, 2001
    Date of Patent: August 2, 2005
    Inventors: Dennis Cvitkovitch, Peter C. Y. Lau, Yung Hua Li
  • Signal peptides, nucleic acid molecules and methods for treatment of caries
    Publication number: 20050152853
    Abstract: Compounds that competitively inhibit binding of CSP to S. mutans histidine kinase are provided. The compounds are preferably a peptide or an antibody, and are preferably a derivative of [SEQ ID NO:2], a fragment of [SEQ ID NO:2] or a derivative of a fragment of [SEQ ID NO:2]. Methods of making these compounds and their use for inhibiting the growth of S. mutans, for inhibiting dental caries, and for improving dental health are also disclosed.
    Type: Application
    Filed: December 6, 2004
    Publication date: July 14, 2005
    Inventors: Yi-Chen Huang, Celine Levesque, Dennis Cvitkovitch
  • Signal peptides, nucleic acid molecules and methods for treatment of caries
    Publication number: 20020081302
    Abstract: The invention relates to a compound that competitively inhibits binding of CSP to S. mutans histidine kinase. The compound is preferably a peptide or an antibody. The compound is preferably a derivative of [SEQ ID NO:2], a fragment of [SEQ ID NO:2] or a derivative of a fragment of [SEQ ID NO:2].
    Type: Application
    Filed: September 17, 2001
    Publication date: June 27, 2002
    Inventors: Dennis Cvitkovitch, Peter C.Y. Lau, Yung Hua Li