Abstract: The subject invention provides a detergent composition comprising an effective amount of a soluble potassium salt, a sodium (C8-C24) alkylsulfate in an amount effective to remove or loosen debris and/or stains from a surface, and a polar surfactant, said surfactant comprising a hydrophobic portion selected from a (C6-C30) alkyl group and a polymeric silicone group, wherein the molar ratio of the surfactant to the sodium (C8-C24) alkylsulfate is greater than or equal to about 1:1. Detergent compositions of the invention include oral compositions for removing and loosening plaque and/or stains from a dental surface and oral compositions for reducing dental nerve and/or dentin sensitivity.

Abstract: The subject invention provides compositions useful in oral cavity, comprising an effective amount of a soluble potassium salt, a sodium (C2–C24) alkylsulfate in an amount effective to remove or loosen debris and/or stains from a surface, and a polar surfactant, said surfactant comprising a hydrophobic portion selected from a (C6–C30) alkyl group and a polymeric silicone group, wherein the molar ratio of the surfactant to the sodium (C8–C24) alkylsulfate is greater than or equal to about 1:1. The subject invention also provides a mint flavoring that does not comprise a substantial amount of menthol, said mint flavoring being either a dementholated natural mint extract or a synthetic blend.

Abstract: The subject invention provides a detergent composition comprising an effective amount of a soluble potassium salt, a sodium (C8-C24) alkylsulfate in an amount effective to remove or loosen debris and/or stains from a surface, and a polar surfactant, said surfactant comprising a hydrophobic portion selected from a (C6-C30) alkyl group and a polymeric silicone group, wherein the molar ratio of the surfactant to the sodium (C8-C24) alkylsulfate is greater than or equal to about 1:1. Detergent compositions of the invention include oral compositions for removing and loosening plaque and/or stains from a dental surface and oral compositions for reducing dental nerve and/or dentin sensitivity.

Abstract: An oral rinse, dentifrice, or oral gel composition comprising:

Abstract: An oral rinse, dentifrice, or oral gel composition comprising: a) about 0.01 weight % to about 5 weight % of a citrus flavor, citrus flavor ingredient, or mixtures thereof; b) about 0.01 weight % to about 5 weight % of a phenolic, said phenolic selected from the group consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures thereof; and c) an orally acceptable carrier. The claimed composition is useful in retarding the development of plaque, treating gingivitis, and reducing the viable population of micro-organisms in the oral cavity of a mammal.

Abstract: An oral rinse, dentifrice, or oral gel composition comprising:

Abstract: An oral rinse, dentifrice, or oral gel composition comprising:

Abstract: Oral rinse and dentifrice compositions, comprising a mint flavor, mint flavor ingredient, citrus flavor, citrus flavor ingredient, phenolic ingredient, or mixtures thereof, said phenolic ingredient selected from the group consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures thereof; a cyclodextrin selected from the group consisting of hydroxypropyl &bgr;-cyclodextrin, hydroxyethyl &bgr;-cyclodextrin, hydroxypropyl &ggr;-cyclodextrin, hydroxyethyl &ggr;-cyclodextrin, &agr;-cyclodextrin, methyl &bgr;-cyclodextrin, and mixtures thereof; and from about 0.1% by weight to about 10% by weight of hydrogen peroxide. These compositions are useful in retarding the development of plaque, treating gingivitis, and in treating the presence of micro-organisms in the oral cavity.

Abstract: Oral rinse and dentifrice compositions, comprising a phenolic selected from the group consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures thereof; and a cyclodextrin selected from the group consisting of hydroxypropyl &bgr;-cyclodextrin, hydroxyethyl &bgr;-cyclodextrin, hydroxypropyl &ggr;-cyclodextrin, hydroxyethyl &ggr;-cyclodextrin, &agr;-cyclodextrin, methyl &bgr;-cyclodextrin, and mixtures thereof. These compositions are useful in retarding the development of plaque, treating gingivitis, and in treating the presence of micro-organisms in the oral cavity.

Abstract: Oral rinse and dentifrice compositions, comprising a phenolic selected from the group consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures thereof; and a cyclodextrin selected from the group consisting of hydroxypropyl &bgr;-cyclodextrin, hydroxyethyl &bgr;-cyclodextrin, hydroxypropyl &ggr;-cyclodextrin, hydroxyethyl &ggr;-cyclodextrin, &agr;-cyclodextrin, methyl &bgr;-cyclodextrin, and mixtures thereof. These compositions are useful in retarding the development of plaque, treating gingivitis, and in treating the presence of micro-organisms in the oral cavity.

Abstract: An oral rinse, dentifrice, or oral gel composition comprising: a) about 0.01 weight % to about 5 weight % of a citrus flavor, citrus flavor ingredient, or mixtures thereof; b) about 0.01 weight % to about 5 weight % of a phenolic, said phenolic selected from the group consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures thereof; and c) an orally acceptable carrier. The claimed composition is useful in retarding the development of plaque, treating gingivitis, and reducing the viable population of micro-organisms in the oral cavity of a mammal.

Abstract: A stable oral rinse or clear oral gel composition, comprising:a) about 0.01% by weight to about 1% by weight of hydrated zinc cations;b) about 0.01% by weight to about 4% by weight of fully or partially protonated citrate moieties;c) about 0.01% by weight to about 2% by weight of cetyl pyridinium cations; andd) an orally acceptable vehicle;wherein said composition has a pH of from about 3.0 to about 4.5.

Abstract: An oral rinse, dentifrice, or oral gel composition comprising:a) about 0.01 weight % to about 5 weight % of a citrus flavor, citrus flavor ingredient, or mixtures thereof;b) about 0.01 weight % to about 5 weight % of a phenolic, said phenolic selected from the group consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures thereof; andc) an orally acceptable carrier.The claimed composition is useful in retarding the development of plaque, treating gingivitis, and reducing the viable population of micro-organisms in the oral cavity of a mammal.

Abstract: Oral rinse and dentifrice compositions, comprising a phenolic selected from the group consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures thereof; and a cyclodextrin selected from the group consisting of hydroxypropyl .beta.-cyclodextrin, hydroxyethyl .beta.-cyclodextrin, hydroxypropyl .gamma.-cyclodextrin, hydroxyethyl .gamma.-cyclodextrin, .alpha.-cyclodextrin, methyl .beta.-cyclodextrin, and mixtures thereof. These compositions are useful in retarding the development of plaque, treating gingivitis, and in treating the presence of micro-organisms in the oral cavity.

Abstract: The subject invention encompasses methods and compositions comprising phosphate derivatives of triclosan for treating or preventing dental plaque, gingivitis or periodontal disease, of the oral cavity in humans or lower animals.

Abstract: Methods for the treatment of a human or lower animal subject having an H. pylori-mediated upper gastrointestinal disorder comprising administering to said subject a safe and effective amount of a diphenyl ether phosphate ester of the following formula: ##STR1## wherein n is an integer from 0 to 3, or a pharmaceutically-acceptable salt thereof.

Abstract: The present invention relates to quaternary nitrogen-containing phosphonate compounds, and the pharmaceutically-acceptable salts and esters thereof and having the general structure: ##STR1## wherein R.sup.1, R.sup.2, R.sup.5 and R.sup.8 are defined in claim 1, m and n are integers from 0 to 10; m+n is from 0 to 10;Z is a saturated, unsaturated, or aromatic, monocyclic or polycyclic carbocycle or monocyclic or polycyclic heterocycle containing one or more heteroatoms selected from O, S, or N, wherein at least one heteroatom is a quaternary nitrogen atom;R is COOH; PO.sub.3 H.sub.2 ; SO.sub.3 H; or P(O)(OH)R.sub.4, wherein R.sub.4 is substituted or unsubstituted alkyl of 1-8 carbon atoms;The present invention further relates to pharmaceutical compositions containing a safe and effective amount of a compound of the present invention, and pharmaceutically-acceptable excipients.

Abstract: A method for bonding of restorative materials, such as composite resins, to the surface of a tooth wherein the surface of the tooth is pretreated with a carbon dioxide laser of low energy density without damaging surrounding tissues or the underlying pulp of the tooth.