Abstract: The present invention provides compositions, uses and methods thereof, for inhibiting the growth of caries-causing bacteria. The composition comprises xylitol, sodium citrate, sodium bicarbonate, anionic polymers and acceptable carrier materials. The compositions can tend to be used for treating or preventing a condition caused by caries-causing bacteria The compositions can further tend to be used in patients such as children, adolescents or patients suffering from a heightened susceptibility to toxic substances.

Abstract: A continuous flow system for passing fluid over a biofilm to simulate an oral environment is described. In one embodiment, the continuous flow system includes a plurality of channels fluidly connected by one or more channel connectors, an inflow conduit defining an inflow channel and an outflow conduit defining an outflow channel. The plurality of channels can receive the fluid via the inflow conduit from a reservoir positioned upstream of the flow cell housing and the outflow channel can receive the fluid from the plurality of channels.

Abstract: Provided are compositions comprising an orally acceptable carrier, an extract of Myristica fragrans derived from nutmeg or mace, and an extract of Vaccinium subgenus Oxycoccus. The compositions may also include an extract of neem and Competence Stimulating Peptide (CSP). Also provided is a method for inhibiting the growth of Streptococcus mutans in a biofilm in the oral cavity of a subject, the method comprising administering to the oral cavity of the subject a composition comprising an orally acceptable carrier, an extract of Myristica fragrans derived from nutmeg or mace, an extract of Vaccinium subgenus Oxycoccus, wherein administering the composition selectively inhibits the rate of growth of Streptococcus mutans over the rate of growth of at least one species of non-Streptococcus mutans bacteria in the biofilm.

Abstract: Provided are compositions comprising an orally acceptable carrier, an extract of Myristica fragrans derived from nutmeg or mace, and an extract of Vaccinium subgenus Oxycoccus. The compositions may also include an extract of neem and Competence Stimulating Peptide (CSP). Also provided is a method for inhibiting the growth of Streptococcus mutans in a biofilm in the oral cavity of a subject, the method comprising administering to the oral cavity of the subject a composition comprising an orally acceptable carrier, an extract of Myristica fragrans derived from nutmeg or mace, an extract of Vaccinium subgenus Oxycoccus, wherein administering the composition selectively inhibits the rate of growth of Streptococcus mutans over the rate of growth of at least one species of non-Streptococcus mutans bacteria in the biofilm.

Abstract: The present invention provides compositions, uses and methods thereof, for inhibiting the growth of caries-causing bacteria. The composition comprises xylitol, sodium citrate, sodium bicarbonate, anionic polymers and acceptable carrier materials. The compositions can tend to be used for treating or preventing a condition caused by caries-causing bacteria The compositions can further tend to be used in patients such as children, adolescents or patients suffering from a heightened susceptibility to toxic substances.