Patents by Inventor Dennis Higgins

Dennis Higgins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Morphogen-induced dendritic growth
    Publication number: 20060025571
    Abstract: Disclosed are methods and compositions for maintaining neural pathways in a mammal including: enhancing survival of neurons at risk of dying; inducing cellular repair of damaged neurons and neural pathways; stimulating neurons to maintain their differentiated phenotype; and promoting dendritic outgrowth, including maintaining dendritic arbors and regenerating dendritic architecture. In one embodiment, the invention provides means for stimulating CAM expression in neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The methods, devices and compositions include a morphogen or morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration.
    Type: Application
    Filed: September 13, 2005
    Publication date: February 2, 2006
    Applicant: Curis, Inc.
    Inventors: David Rueger, Kuber Sampath, John Smart, Hermann Oppermann, Engin Ozkaynak, Charles Cohen, Dennis Higgins
  • Morphogen-induced dendritic growth
    Patent number: 6949505
    Abstract: Disclosed are methods and compositions for maintaining neural pathways in a mammal including: enhancing survival of neurons at risk of dying; inducing cellular repair of damaged neurons and neural pathways; stimulating neurons to maintain their differentiated phenotype; and promoting dendritic outgrowth, including maintaining dendritic arbors and regenerating dendritic architecture. In one embodiment, the invention provides means for stimulating CAM expression in neurons. The invention also provides means for evaluating the status of nerve tissue, including means for detecting and monitoring neuropathies in a mammal. The methods, devices and compositions include a morphogen or morphogen-stimulating agent provided to the mammal in a therapeutically effective concentration.
    Type: Grant
    Filed: August 18, 1994
    Date of Patent: September 27, 2005
    Assignees: Curis, Inc., The Research Foundation of State University of New York
    Inventors: David C. Rueger, Kuber T. Sampath, John E. Smart, Hermann Oppermann, Engin Ozkaynak, Charles M. Cohen, Dennis Higgins