Patents by Inventor Dennis I. Goldberg
Dennis I. Goldberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8352024Abstract: An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual includes a device shaped to conform with the shape of a portion of an individual's finger from a tip thereof to a location past the first finger joint. A self-contained power source is carried by the device and a first electrode is carried by the device adjacent a distal end portion thereof and the tip of the individual's finger. The first electrode is in electrical contact with the power source. A second electrode is carried by the device for contact with the individual's finger. The second electrode is in electrical contact with the power source. Upon application of the first electrode over a treatment site with the medicament disposed between the first electrode and the treatment site and completion of an electrical circuit through the individual's body and said electrode, the device applies current for electrokinetically driving the medicament into the treatment site.Type: GrantFiled: March 13, 2006Date of Patent: January 8, 2013Assignee: Nitric Biotherapeutics, Inc.Inventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, James Derouin
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Patent number: 8328788Abstract: A method for delivering a substance to an infected nail of an individual is described. The method includes the step of applying a device to at least one infected nail of an individual, where the device includes at least one active electrode and at least one counter electrode, where the at least one counter electrode is in contact with the individual, and where the device is connected to at least one power source. The method also includes the steps of disposing a medicament between the at least one active electrode and the at least one infected nail, applying a salt solution to the at least one infected nail, and providing an electrical current from the power source to the at least one active electrode to facilitate delivery of the medicament into the region of the at least one infected nail.Type: GrantFiled: May 11, 2011Date of Patent: December 11, 2012Assignee: Nitric Biotherapeutics, Inc.Inventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, James Derouin
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Patent number: 8321008Abstract: A device for electrokinetic delivery of medicament to a treatment site includes a cartridge having an active electrode and a membrane overlying the active electrode and a medicament or a medicament and an electrically conductive carrier therefor, carried by the membrane in electrical contact with the electrode. The electrode opens through a surface of the cartridge remote from the membrane for connection with an electrical connector carried by the device. An locking element releasably couples the cartridge to the housing.Type: GrantFiled: November 30, 2006Date of Patent: November 27, 2012Assignee: Nitric Biotherapeutics, Inc.Inventors: John S. Petersen, Dennis I. Goldberg, James W. Kelland, Paul K. Rand, Anthony Patrick Charles Jones, Robert W. Etheredge
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Publication number: 20110213295Abstract: A method for delivering a substance to an infected nail of an individual is described. The method includes the step of applying a device to at least one infected nail of an individual, where the device includes at least one active electrode and at least one counter electrode, where the at least one counter electrode is in contact with the individual, and where the device is connected to at least one power source. The method also includes the steps of disposing a medicament between the at least one active electrode and the at least one infected nail, applying a salt solution to the at least one infected nail, and providing an electrical current from the power source to the at least one active electrode to facilitate delivery of the medicament into the region of the at least one infected nail.Type: ApplicationFiled: May 11, 2011Publication date: September 1, 2011Inventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, James Derouin
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Publication number: 20110208111Abstract: The invention relates to systems and methods for treating a fungal infection of the nail of an individual. In various embodiments, the methods include applying a device to at least one nail of the individual that is infected by a fungus. In various embodiments, the devices include at least one active electrode and at least one counter electrode, with the at least one counter electrode in contact with the individual.Type: ApplicationFiled: April 29, 2011Publication date: August 25, 2011Inventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, James Derouin
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Publication number: 20110071491Abstract: An electrokinetic apparatus to apply medicament to a treatment site of a mammalian user, the apparatus including: a flux concentrator including an active electrode and a counter electrode adapted to be applied to the surface of a toenail or fingernail of the user, and a medicament matrix adjacent the active electrode and arranged to be sandwiched between the active electrode and nail.Type: ApplicationFiled: December 1, 2010Publication date: March 24, 2011Inventors: Michael S. Barsness, Robert W. Etheredge, Dennis I. Goldberg, Bireswar Chakraborty, Shawn P. Davis
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Publication number: 20080319371Abstract: A method to electrokinetically deliver a medicament to a nail of a mammalian user including: forming a cast of the nail of the user wherein the cast is a reverse impression of the nail; applying a medicament matrix to the nail; sandwiching the medicament matrix between the cast and the nail; pressing the medicament matrix to the nail using the cast; applying electrical current to an electrical current path extending through the medicament matrix and the nail, and delivering medicament from the matrix into the nail by electrokinetic transporting the medicament along the current path.Type: ApplicationFiled: June 19, 2008Publication date: December 25, 2008Applicant: TRANSPORT PHARMACEUTICALS, INC.Inventors: Robert W. Etheredge, Dennis I. Goldberg, Shawn P. Davis, Bireswar Chakraborty, Michael S. Barsness
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Publication number: 20080312579Abstract: An electrokinetic apparatus to apply medicament to a treatment site of a mammalian user, the apparatus including: a segmented active electrode; a medicament matrix having one side abutting the segmented active electrode and another side adapted to contact a surface of skin over the treatment site, wherein the matrix includes at least one current direction barrier suppressing transverse current flow through the matrix.Type: ApplicationFiled: June 16, 2008Publication date: December 18, 2008Applicant: TRANSPORT PHARMACEUTICALS, INC.Inventors: Kuowei Chang, Dennis I. Goldberg, Robert W. Etheredge, Michael S. Barsness
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Publication number: 20080312580Abstract: An electrokinetic apparatus to apply medicament to a treatment site of a mammalian user, the apparatus including: a flux concentrator including an active electrode and a counter electrode adapted to be applied to the surface of a toenail or fingernail of the user, and a medicament matrix adjacent the active electrode and arranged to be sandwiched between the active electrode and nail.Type: ApplicationFiled: June 16, 2008Publication date: December 18, 2008Applicant: TRANSPORT PHARMACEUTICALS, INC.Inventors: Michael S. Barsness, Robert W. Etheredge, Dennis I. Goldberg, Bireswar Chakraborty, Shawn P. Davis
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Patent number: 7127285Abstract: A system for delivering a substance into a body at a treatment site that includes an alternating current source and a plurality of electrodes. Circuitry is connected between the alternating current source and the electrodes for supplying current to the electrodes when the electrodes are in electrical contact with said body so that a uni-directional current flow for delivering the substance into the body is maintained at the treatment site and a bi-directional current flow is maintained throughout the body. At least one of the electrodes is divided into sub-electrodes to, for example, reduce hazards associated with current concentration. These and other systems and methods are adaptable for large treatment areas and/or use a convenient and low-cost arrangement of electronics.Type: GrantFiled: February 7, 2003Date of Patent: October 24, 2006Assignee: Transport Pharmaceuticals Inc.Inventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, James Derouin
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Patent number: 7069073Abstract: An electrokinetic delivery or diagnostic device for personal use and self-administration of a medicament to a treatment site is provided. The device includes a housing containing a power supply, a first active electrode and a ground tactile electrode. An applicator includes a pad for containing medicament for overlying the first electrode of the device. The medicament may be applied by the user to the pad, contained within the pad or contained in rupturable capsules within the pad, together with a hydrogel if necessary for imparting electrical conductivity whereby, upon application of the applicator to the treatment site, the medicament is electrokinetically transported into the treatment site.Type: GrantFiled: March 24, 2004Date of Patent: June 27, 2006Assignee: BioPhoretic Therapeutic Systems, LLCInventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, Christopher H. Porter, V. Lorenzo Porcelli
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Patent number: 7016724Abstract: An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual includes a device shaped to conform with the shape of a portion of an individual's finger from a tip thereof to a location past the first finger joint. A self-contained power source is carried by the device and a first electrode is carried by the device adjacent a distal end portion thereof and the tip of the individual's finger. The first electrode is in electrical contact with the power source. A second electrode is carried by the device for contact with the individual's finger. The second electrode is in electrical contact with the power source. Upon application of the first electrode over a treatment site with the medicament disposed between the first electrode and the treatment site and completion of an electrical circuit through the individual's body and said electrode, the device applies current for electrokinetically driving the medicament into the treatment site.Type: GrantFiled: December 1, 2003Date of Patent: March 21, 2006Assignee: Transport Pharmaceuticals, Inc.Inventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg
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Patent number: 6792306Abstract: An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual includes a device shaped to conform with the shape of a portion of an individual's finger from a tip thereof to a location past the first finger joint. A self-contained power source is carried by the device and a first electrode is carried by the device adjacent a distal end portion thereof and the tip of the individual's finger. The first electrode is in electrical contact with the power source. A second electrode is carried by the device for contact with the individual's finger. The second electrode is in electrical contact with the power source.Type: GrantFiled: April 8, 2002Date of Patent: September 14, 2004Assignee: Biophoretic Therapeutic Systems, LLCInventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg
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Publication number: 20040176737Abstract: An electrokinetic delivery or diagnostic device for personal use and self-administration of a medicament to a treatment site is provided. The device includes a housing containing a power supply, a first active electrode and a ground tactile electrode. An applicator includes a pad for containing medicament for overlying the first electrode of the device. The medicament may be applied by the user to the pad, contained within the pad or contained in rupturable capsules within the pad, together with a hydrogel if necessary for imparting electrical conductivity whereby, upon application of the applicator to the treatment site, the medicament is electrokinetically transported into the treatment site.Type: ApplicationFiled: March 24, 2004Publication date: September 9, 2004Applicant: Biophoretic Therapeutic Systems, LLCInventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, Christopher H. Porter, V. Lorenzo Porcelli
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Publication number: 20040111051Abstract: An electrokinetic delivery system for personal use in self-administration of a medicament to a treatment site on an individual includes a device shaped to conform with the shape of a portion of an individual's finger from a tip thereof to a location past the first finger joint. A self-contained power source is carried by the device and a first electrode is carried by the device adjacent a distal end portion thereof and the tip of the individual's finger. The first electrode is in electrical contact with the power source. A second electrode is carried by the device for contact with the individual's finger. The second electrode is in electrical contact with the power source. Upon application of the first electrode over a treatment site with the medicament disposed between the first electrode and the treatment site and completion of an electrical circuit through the individual's body and said electrode, the device applies current for electrokinetically driving the medicament into the treatment site.Type: ApplicationFiled: December 1, 2003Publication date: June 10, 2004Applicant: BioPhoretic Therapeutic Systems, LLC.Inventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg
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Patent number: 6735470Abstract: An electrokinetic delivery or diagnostic device for personal use and self-administration of a medicament to a treatment site is provided. The device includes a housing containing a power supply, a first active electrode and a ground tactile electrode. An applicator includes a pad for containing medicament for overlying the first electrode of the device. The medicament may be applied by the user to the pad, contained within the pad or contained in rupturable capsules within the pad, together with a hydrogel if necessary for imparting electrical conductivity whereby, upon application of the applicator to the treatment site, the medicament is electrokinetically transported into the treatment site.Type: GrantFiled: September 18, 2002Date of Patent: May 11, 2004Assignee: BioPhoretic Therapeutic Systems, LLCInventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, Christopher H. Porter, V. Lorenzo Porcelli
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Publication number: 20030199808Abstract: A system for delivering a substance into a body at a treatment site that includes an alternating current source and a plurality of electrodes. Circuitry is connected between the alternating current source and the electrodes for supplying current to the electrodes when the electrodes are in electrical contact with said body so that a unidirectional current flow for delivering the substance into the body is maintained at the treatment site and a bidirectional current flow is maintained throughout the body. At least one of the electrodes is divided into sub-electrodes to, for example, reduce hazards associated with current concentration. These and other systems and methods are adaptable for large treatment areas and/or use a convenient and low-cost arrangement of electronics.Type: ApplicationFiled: February 7, 2003Publication date: October 23, 2003Applicant: Biophoretic Therapeutic Systems, LLC.Inventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, James Derouin
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Publication number: 20030086898Abstract: A method for removing bile salts from a patient that includes administering to the patient a therapeutically effective amount of a non-absorbable amine polymers characterized by a repeat unit having the formula: 1Type: ApplicationFiled: May 29, 2002Publication date: May 8, 2003Applicant: GelTex Pharmaceuticals, Inc.Inventors: Stephen Randall Holmes-Farley, W. Harry Mandeville, Steven K. Burke, Dennis I. Goldberg
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Publication number: 20030018295Abstract: An electrokinetic delivery or diagnostic device for personal use and self-administration of a medicament to a treatment site is provided. The device includes a housing containing a power supply, a first active electrode and a ground tactile electrode. An applicator includes a pad for containing medicament for overlying the first electrode of the device. The medicament may be applied by the user to the pad, contained within the pad or contained in rupturable capsules within the pad, together with a hydrogel if necessary for imparting electrical conductivity whereby, upon application of the applicator to the treatment site, the medicament is electrokinetically transported into the treatment site.Type: ApplicationFiled: September 18, 2002Publication date: January 23, 2003Applicant: BIOPHORETIC THERAPEUTIC SYSTEMS, LLCInventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, Christopher H. Porter, V. Lorenzo Porcelli
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Patent number: 6477410Abstract: An electrokinetic delivery or diagnostic device for personal use and self-administration of a medicament to a treatment site is provided. The device includes a housing containing a power supply, a first active electrode and a ground tactile electrode. An applicator includes a pad for containing medicament for overlying the first electrode of the device. The medicament may be applied by the user to the pad, contained within the pad or contained in rupturable capsules within the pad, together with a hydrogel if necessary for imparting electrical conductivity whereby, upon application of the applicator to the treatment site, the medicament is electrokinetically transported into the treatment site.Type: GrantFiled: May 31, 2000Date of Patent: November 5, 2002Assignee: BioPhoretic Therapeutic Systems, LLCInventors: Julian L. Henley, Kuo Wei Chang, Joseph Potter, Dennis I. Goldberg, Christopher H. Porter, V. Lorenzo Porcelli