Abstract: The instant disclosure provides antibodies that specifically bind to CTLA-4 (e.g., human CTLA-4) and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: Cold-sprayed aluminum capacitors on lead frame metal foils are provided for applications in 3D power package integration. This additive manufacturing process allows pre-patterned low-temperature processing of aluminum electrodes on metal lead frames, insulated metal substrates or even heat-spreaders and cold-plates. Cold-sprayed capacitors can eliminate several process integration and reliability issues that are associated with traditional discrete surface-assembled capacitors.

Abstract: Cold-sprayed aluminum capacitors on lead frame metal foils are provided for applications in 3D power package integration. This additive manufacturing process allows pre-patterned low-temperature processing of aluminum electrodes on metal lead frames, insulated metal substrates or even heat-spreaders and cold-plates. Cold-sprayed capacitors can eliminate several process integration and reliability issues that are associated with traditional discrete surface-assembled capacitors.

Abstract: Methods for large-scale additive manufacturing of high-strength boron nitride nanotubes (BNNT)/aluminum (Al) (e.g., reinforced Al alloy) metal matrix composites (MMCs) (BNNT/Al MMCs), as well as the BNNT/Al MMCs produced by the large-scale additive manufacturing methods, are provided. A combination of ultrasonication and spray drying techniques can produce good BNNT/Al alloy feedstock powders, which can be used in a cold spraying process.

Abstract: Provided is a method of repairing structures on the Lunar surface using Lunar regolith containing metallic coatings. An ultra-portable and low-pressure cold spray system is utilized to consolidate coatings. This system can be easily transported to space, reducing the payload. Lunar regolith is added to the metal powder before cold spray deposition. Lunar regolith increases the tampering effect during cold spray deposition, thereby causing severe plastic deformation of the metal powders and providing a coating with high quality and minimum porosity. The presence of Lunar regolith increases the hardness of the coating and improves wear properties. Coatings on a large area can be made rapidly without much surface preparation. These coatings can be rapidly applied to various Lunar structures to repair, reinforce, and restore (RRR) functionality and performance in the Lunar environment.

Abstract: The instant disclosure provides antibodies that specifically bind to TIM 3 and antagonize TIM-3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: Methods for large-scale additive manufacturing of high-strength boron nitride nanotubes (BNNT)/aluminum (Al) (e.g., reinforced Al alloy) metal matrix composites (MMCs) (BNNT/Al MMCs), as well as the BNNT/Al MMCs produced by the large-scale additive manufacturing methods, are provided. A combination of ultrasonication and spray drying techniques can produce good BNNT/Al alloy feedstock powders, which can be used in a cold spraying process.

Abstract: A robotic system is configured to autonomously or semi-autonomously rack a circuit breaker from an electrical cabinet or other electrical-connection station. The robotic system may perform work on circuit breakers, ground-and-test devices, or other electrical equipment.

Abstract: The instant disclosure provides antibodies that specifically bind to TIM-3 (e.g., human TIM-3) and antagonize TIM-3 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: The instant disclosure provides antibodies that specifically bind to T-cell immunoreceptor with Ig and ITIM domains (TIGIT) (e.g., human TIGIT) and antagonize TIGIT function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: Methods for large-scale additive manufacturing of high-strength boron nitride nanotubes (BNNT)/aluminum (Al) (e.g., reinforced Al alloy) metal matrix composites (MMCs) (BNNT/Al MMCs), as well as the BNNT/Al MMCs produced by the large-scale additive manufacturing methods, are provided. A combination of ultrasonication and spray drying techniques can produce good BNNT/Al alloy feedstock powders, which can be used in a cold spraying process.

Abstract: Methods for large-scale additive manufacturing of high-strength boron nitride nanotubes (BNNT)/aluminum (Al) (e.g., reinforced Al alloy) metal matrix composites (MMCs) (BNNT/Al MMCs), as well as the BNNT/Al MMCs produced by the large-scale additive manufacturing methods, are provided. A combination of ultrasonication and spray drying techniques can produce good BNNT/Al alloy feedstock powders, which can be used in a cold spraying process.

Abstract: Antibodies that specifically bind to TIM 3 and antagonize TIM-3 function pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: A phytosanitary treatment blockchain is generated from automatically gathered phytosanitary treatment records. The phytosanitary treatment records are generated by matching authenticated treatment data with authenticated identification data. Matching may be based on geolocation, timestamps, or both. Authentication may be based on digital signatures using private key encryption. Separate treatment sensors and identification sensors automatically gather information about a phytosanitary treatment and the item being treated. The gathered information is encrypted and transmitted to blockchain members that perform authentication, matching, and generation of the phytosanitary treatment blockchain. A tracking code may be issued for each treatment. The tracking code is used to obtain an authentication of the treatment that indicates whether the treatment passed or failed.

Abstract: A method of deliquification of production wells includes placing an artificial lift tool in a gas wellbore, where the artificial lift tool includes a rack and multiple piezoelectric transducers. The rack includes multiple trays. Each piezoelectric transducer of the multiple piezoelectric transducers is positioned on a respective tray of the multiple trays. The method further includes providing, by a pump, a liquid on surfaces of the multiple piezoelectric transducers and providing, by a signal source, an electrical signal to the multiple piezoelectric transducers. The method also includes generating, by the multiple piezoelectric transducers, acoustic waves from the electrical signal, where at least some of the liquid provided to the multiple piezoelectric transducers is atomized by the acoustic waves.

Abstract: Methods for large-scale additive manufacturing of high-strength boron nitride nanotubes (BNNT)/aluminum (Al) (e.g., reinforced Al alloy) metal matrix composites (MMCs) (BNNT/Al MMCs), as well as the BNNT/Al MMCs produced by the large-scale additive manufacturing methods, are provided. A combination of ultrasonication and spray drying techniques can produce good BNNT/Al alloy feedstock powders, which can be used in a cold spraying process.

Abstract: Methods for large-scale additive manufacturing of high-strength boron nitride nanotubes (BNNT) / aluminum (Al) (e.g., reinforced Al alloy) metal matrix composites (MMCs) (BNNT/A1 MMCs), as well as the BNNT/A1 MMCs produced by the large-scale additive manufacturing methods, are provided. A combination of ultrasonication and spray drying techniques can produce good BNNT/Al alloy feedstock powders, which can be used in a cold spraying process.

Abstract: The instant disclosure provides antibodies that specifically bind to CTLA-4 (e.g., human CTLA-4) and antagonize CTLA-4 function. Also provided are pharmaceutical compositions comprising these antibodies, nucleic acids encoding these antibodies, expression vectors and host cells for making these antibodies, and methods of treating a subject using these antibodies.

Abstract: An airport runway arrangement for commercial aircraft comprises a first runway section, a second runway section extending substantially in prolongation of the first runway section and an intermediate section between the first and second runway sections.

Abstract: Provided are novel antigenic polypeptides comprising tumor-associated peptides, and compositions comprising the same. Such antigenic polypeptides and compositions are particularly useful as immunotherapeutics (e.g., cancer vaccines). Also provided are methods of inducing a cellular immune response using the polypeptides and compositions, methods of treating a disease using the polypeptides and compositions, kits comprising the polypeptides and compositions, methods of making the compositions, and antibodies and T cell receptors that specifically bind to the polypeptides.