Patents by Inventor Dennis M. Downing

Dennis M. Downing has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperazine derivative renin inhibitors
    Publication number: 20040214832
    Abstract: Disclosed are piperazine derivatives, their manufacture and use as inhibitors of renin.
    Type: Application
    Filed: March 26, 2004
    Publication date: October 28, 2004
    Inventors: Cuiman Cai, Emma Hazel Clay, Dennis M. Downing, Jeremy John Edmunds, Daniel Dale Holsworth, Tingsheng Li, Noel Aaron Powell
  • Sulfonylquinolines as central nervous system and cardiovascular agents
    Patent number: 5552411
    Abstract: Sulfonylquinolines are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as antiobesity agents and for the treatment of hypertension.
    Type: Grant
    Filed: May 26, 1995
    Date of Patent: September 3, 1996
    Assignee: Warner-Lambert Company
    Inventors: Dennis M. Downing, Jonathan L. Wright
  • Benzimidazoles and imidazopyridines as central nervous system agents
    Patent number: 5486517
    Abstract: Benzimidazoles and imidazopyridines are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as antipsychotic agents and for the treatment of disorders which respond to dopaminergic blockade including psychotis depression, substance abuse, and compulsive disorders.
    Type: Grant
    Filed: May 10, 1994
    Date of Patent: January 23, 1996
    Assignee: Warner-Lambert Company
    Inventors: Dennis M. Downing, Shelly A. Glase, Stephen J. Johnson, Lawrence D. Wise, Jonathan L. Wright
  • Dimeric benzimidazoles as central nervous system agents
    Patent number: 5414010
    Abstract: Dimeric benzimidazoles are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as antipsychotic agents and for the treatment of disorders which respond to dopaminergic blockade including psychotic depression, substance abuse, and compulsive disorders.
    Type: Grant
    Filed: May 10, 1994
    Date of Patent: May 9, 1995
    Assignee: Warner-Lambert Company
    Inventors: Dennis M. Downing, Lawrence D. Wise, Jonathan L. Wright
  • 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents
    Patent number: 5409931
    Abstract: 1,3-Substituted cycloalkenes and cycloalkanes are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as dopaminergic, antipsychotic, and antihypertensive agents as well as for treating hyperprolactinaemia-related conditions and central nervous system disorders.
    Type: Grant
    Filed: February 4, 1994
    Date of Patent: April 25, 1995
    Assignee: Warner-Lambert Company
    Inventors: Bradley W. Caprathe, Dennis M. Downing, Juan C. Jaen, Stephen J. Johnson, William J. Smith, III, Lawrence D. Wise, Jonathan Wright, David J. Wustrow
  • 1,3-substituted cycloalkenes and cycloalkanes as central nervous system agents
    Patent number: 5314896
    Abstract: 1,3-Substituted cycloalkenes and cycloalkanes are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful as central nervous system agents and are particularly useful as dopaminergic, antipsychotic, and antihypertensive agents as well as for treating hyperprolactinaemia-related conditions and central nervous system disorders.
    Type: Grant
    Filed: October 15, 1992
    Date of Patent: May 24, 1994
    Assignee: Warner-Lambert Company
    Inventors: Bradley W. Caprathe, Dennis M. Downing, Juan C. Jaen, Stephen J. Johnson, William J. Smith, III, Lawrence D. Wise, Jonathan Wright, David J. Wustrow