Patents by Inventor Dennis M. Treu

Dennis M. Treu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240366849
    Abstract: Peritoneal dialysis admixing and/or treatment devices, methods, and systems are disclosed. The systems, methods, and devices provide high-level guarantees of sterility and employ relatively inexpensive disposable components to provide pumping. Disclosed systems, methods, and devices and features thereof are adapted for point of use generation of medicament. In particular, admixing systems that employ independently-replaceable long term concentrate are disclosed. Features are directed to assurance of sterility and accurate admixing of water and concentrate to generate ready-to-use medicaments and other benefits.
    Type: Application
    Filed: July 16, 2024
    Publication date: November 7, 2024
    Applicant: NxStage Medical, Inc.
    Inventors: Mark T. WYETH, Gregory YANTZ, James Ian JOHNSON, James M. BRUGGER, Dennis M. TREU, Dritan KURSHUMI, Jeffrey H. BURBANK, William J. SCHNELL, Robert Paul MCCARTY
  • Patent number: 12112849
    Abstract: A medical treatment device is configured to be used during a treatment session at a first location and includes a medical treatment component configured to perform at least one of hemodialysis, hemofiltration, and peritoneal dialysis on a patient during the treatment session at the first location. The device also includes a monitoring system configured to receive data from one or more sensors connected to the monitoring system, and to confirm a presence of an authorized helper at the first location. A user interface permits an operator to control functions of the medical treatment component and the monitoring system is configured to perform the presence confirmation automatically and at the predefined time intervals during the treatment session. The monitoring system is also configured to generate an alarm and to cause the medical treatment component to go into a failsafe operational mode.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: October 8, 2024
    Assignee: NxStage Medical, Inc.
    Inventors: Jeffrey H. Burbank, Dennis M. Treu, James M. Brugger
  • Publication number: 20240293659
    Abstract: A method of controlling flow through a flexible tube includes providing a pinch clamp mechanism including a pinching element and a pinching surface configured to apply a force on the flexible tube when the flexible tube is positioned between the pinching element and the pinching surface. The method also includes displacing the pinching element relative to the pinching surface with a mechanical drive unit and biasing the pinching element toward the pinching surface with a spring.
    Type: Application
    Filed: May 13, 2024
    Publication date: September 5, 2024
    Applicant: NxStage Medical, Inc.
    Inventors: Scott W. NEWELL, Dennis M. TREU, Kenneth E. BUCKLER
  • Publication number: 20240277909
    Abstract: A medicament preparation system includes a water purification module and a medicament proportioning module that is interoperable with a replaceable fluid circuit. The fluid circuit includes a purified water inlet, a product medicament outlet, and a plurality of pumping tube segments. At least a first concentrate container is connected by at least a portion of the fluid circuit to the product medicament output and a first concentration measurement sensor station is positioned in a flow path. A controller is programmed to calculate iteratively a concentration of a first concentrate from the first concentrate container and the purified water from a signal generated by the first concentration measurement sensor station and to regulate one or both of a first pumping actuator engaged with the first pumping tube segment and a second pumping actuator engaged with the second pumping tube segment, responsively to the concentration of the first concentrate and water.
    Type: Application
    Filed: April 29, 2024
    Publication date: August 22, 2024
    Applicant: NxStage Medical, Inc.
    Inventors: Goetz FRIEDERICHS, William K. WEIGEL, Dennis M. TREU, Jeffrey H. BURBANK, James M. BRUGGER, Keith David J. WHEELER, Scott W. NEWELL
  • Publication number: 20240277910
    Abstract: A medical treatment system includes a disposable fluid circuit that includes a water inlet and a batch container arranged to hold a mixture, the mixture including water that is received from the water inlet and at least one concentrate. The fluid circuit also includes a drain line for draining fluid from the disposable fluid circuit, and a manifold with a plurality of fluid lines, the manifold connecting the water inlet, the batch container, a source of the at least one concentrate, and the drain line. A source of purified water supplies the purified water to the water inlet and a sensor detects a property of fluid in the disposable fluid circuit. A controller controls flowing of a first fluid followed by displacement by a second fluid causing the first fluid to flow to the sensor.
    Type: Application
    Filed: April 10, 2024
    Publication date: August 22, 2024
    Applicant: NxStage Medical, Inc.
    Inventors: Jeffrey H. BURBANK, James M. BRUGGER, Dennis M. TREU, Mark T. WYETH
  • Patent number: 12048791
    Abstract: Peritoneal dialysis admixing and/or treatment devices, methods, and systems are disclosed. The systems, methods, and devices provide high-level guarantees of sterility and employs relatively inexpensive disposable components to provide pumping. Disclosed systems, methods, and devices and features thereof are adapted for point of use generation of medicament. In particular admixing systems that employ independently-replaceable long term concentrate are disclosed. Features are directed to assurance of sterility and accurate admixing of water and concentrate to generate ready-to-use medicaments and other benefits.
    Type: Grant
    Filed: June 24, 2018
    Date of Patent: July 30, 2024
    Assignee: NxStage Medical, Inc.
    Inventors: Mark T. Wyeth, Gregory Yantz, James Ian Johnson, James M. Brugger, Dennis M. Treu, Dritan Kurshumi, Jeffrey H. Burbank, William J. Schnell, Robert Paul McCarty
  • Patent number: 12005224
    Abstract: A method of controlling flow through a flexible tube includes providing a pinch clamp mechanism including a pinching element and a pinching surface configured to apply a force on the flexible tube when the flexible tube is positioned between the pinching element and the pinching surface. The method also includes displacing the pinching element relative to the pinching surface with a mechanical drive unit and biasing the pinching element toward the pinching surface with a spring.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: June 11, 2024
    Assignee: NxStage Medical, Inc.
    Inventors: Scott W. Newell, Dennis M. Treu, Kenneth E. Buckler
  • Publication number: 20240181145
    Abstract: A blood treatment system employing at least two pumps for performing a low blood flow treatment is operable for high blood flow treatments such as extracorporeal membrane oxygenation (ECMO) by providing a fluid circuit with parallel blood flow paths and recruiting multiple ones of the pumps for parallel blood flow.
    Type: Application
    Filed: February 15, 2024
    Publication date: June 6, 2024
    Applicant: NxStage Medical, Inc.
    Inventor: Dennis M. TREU
  • Patent number: 11986582
    Abstract: A medicament preparation system includes a water purification module and a medicament proportioning module that is interoperable with a replaceable fluid circuit. The fluid circuit includes a purified water inlet, a product medicament outlet, and a plurality of pumping tube segments. At least a first concentrate container is connected by at least a portion of the fluid circuit to the product medicament output and a first concentration measurement sensor station is positioned in a flow path. A controller is programmed to calculate iteratively a concentration of a first concentrate from the first concentrate container and the purified water from a signal generated by the first concentration measurement sensor station and to regulate one or both of a first pumping actuator engaged with the first pumping tube segment and a second pumping actuator engaged with the second pumping tube segment, responsively to the concentration of the first concentrate and water.
    Type: Grant
    Filed: October 26, 2021
    Date of Patent: May 21, 2024
    Assignee: NxStage Medical, Inc.
    Inventors: Goetz Friederichs, William K. Weigel, Dennis M. Treu, Jeffrey H. Burbank, James M. Brugger, Keith David J. Wheeler, Scott W. Newell
  • Patent number: 11975131
    Abstract: A medical treatment system includes a disposable fluid circuit that includes a water inlet and a batch container arranged to hold a mixture, the mixture including water that is received from the water inlet and at least one concentrate. The fluid circuit also includes a drain line for draining fluid from the disposable fluid circuit, and a manifold with a plurality of fluid lines, the manifold connecting the water inlet, the batch container, a source of the at least one concentrate, and the drain line. A source of purified water supplies the purified water to the water inlet and a sensor detects a property of fluid in the disposable fluid circuit. A controller controls flowing of a first fluid followed by displacement by a second fluid causing the first fluid to flow to the sensor.
    Type: Grant
    Filed: December 23, 2020
    Date of Patent: May 7, 2024
    Assignee: NxStage Medical, Inc.
    Inventors: Jeffrey H. Burbank, James M. Brugger, Dennis M. Treu, Mark T. Wyeth
  • Publication number: 20240123128
    Abstract: A fluid treatment plant has a filter module including at least a first filter and a second filter connected in series and connectable to a supply of fluid. A pump is fluidly connected to the filter module and a controller with a fluid quality sensor is connected to detect a quality of the fluid between the first filter and the second filter. A filter module detector is connected to the controller configured to uniquely detect a filter module connected to the pump, and the controller is controls the pump responsively to a signal from the fluid quality sensor and the module detector. The controller is configured to continue pumping based on output of the quality sensor and/or based on output from the filter module detector.
    Type: Application
    Filed: December 27, 2023
    Publication date: April 18, 2024
    Applicant: NxStage Medical, Inc.
    Inventors: Jeffrey H. BURBANK, Dennis M. TREU, Goetz FRIEDERICHS, Brian C. GREEN, Christopher S. MCDOWELL, James M. BRUGGER
  • Publication number: 20240091423
    Abstract: A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.
    Type: Application
    Filed: November 29, 2023
    Publication date: March 21, 2024
    Applicant: NxStage Medical, Inc.
    Inventors: Goetz FRIEDERICHS, Dennis M. TREU, Jeffrey H. BURBANK, Yuriy N. TATASHIN
  • Publication number: 20240075191
    Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.
    Type: Application
    Filed: November 14, 2023
    Publication date: March 7, 2024
    Applicant: NxStage Medical, Inc.
    Inventors: Jeffrey H. BURBANK, Dennis M. TREU, Daniel Joseph RUBERY, JR., Scott W. NEWELL, James M. BRUGGER, William J. SCHNELL, William K. WEIGEL, Steven A. WHITE, Mark T. WYETH, Jerome JAMES, David DESOUZA, Joseph E. TURK, JR., Garrett CASEY
  • Patent number: 11918720
    Abstract: A blood treatment system employing at least two pumps for performing a low blood flow treatment is operable for high blood flow treatments such as extracorporeal membrane oxygenation (ECMO) by providing a fluid circuit with parallel blood flow paths and recruiting multiple ones of the pumps for parallel blood flow.
    Type: Grant
    Filed: February 5, 2018
    Date of Patent: March 5, 2024
    Assignee: NxStage Medical, Inc.
    Inventor: Dennis M. Treu
  • Patent number: 11896750
    Abstract: A fluid treatment plant has a filter module including at least a first filter and a second filter connected in series and connectable to a supply of fluid. A pump is fluidly connected to the filter module and a controller with a fluid quality sensor is connected to detect a quality of the fluid between the first filter and the second filter. A filter module detector is connected to the controller configured to uniquely detect a filter module connected to the pump, and the controller is controls the pump responsively to a signal from the fluid quality sensor and the module detector. The controller is configured to continue pumping based on output of the quality sensor and/or based on output from the filter module detector.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: February 13, 2024
    Assignee: NxStage Medical, Inc.
    Inventors: Jeffrey H. Burbank, Dennis M. Treu, Goetz Friederichs, Brian C. Green, Christopher S. Mcdowell, James M. Brugger
  • Patent number: 11865240
    Abstract: A method of automatically ensuring against chloramine contamination in purified product water includes supplying input water to the system and purifying the water to generate the purified product water. The purifying includes removing chlorine and chloramine contamination from the water using a carbon filter and supplying chlorine-depleted water to a deionization filter, and deionizing the chlorine-depleted water using said deionization filter. The product water is supplied to a sensor for continuous monitoring of the resistivity of the purified product water by the first sensor, and an alarm is generated indicating possible chloramine breakthrough when the resistivity of the product water falls below a predetermined resistivity level, which is selected to provide a reserve filter capacity before breakthrough would occur. The carbon filter is replaced at least responsively to the alarm to ensure excess capacity of said carbon filter sufficient to prevent chloramine breakthrough in said product water.
    Type: Grant
    Filed: March 2, 2021
    Date of Patent: January 9, 2024
    Assignee: NxStage Medical, Inc.
    Inventors: Goetz Friederichs, Dennis M. Treu, Jeffrey H. Burbank, Yuriy N. Tatashin
  • Patent number: 11850341
    Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. Volumetric fluid balance, a required element of many such processes, may be achieved with multiple pumps or other proportioning or balancing devices which are to some extent independent of each other. This need may arise in treatments that involve multiple fluids. Safe and secure mechanisms to ensure fluid balance in such systems are described.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: December 26, 2023
    Assignee: NxStage Medical, Inc.
    Inventors: Jeffrey H. Burbank, Dennis M. Treu, Daniel Joseph Rubery, Jr., Scott W. Newell, James M. Brugger, William J. Schnell, William K. Weigel, Steven A. White, Mark T. Wyeth, Jerome James, David Desouza, Joseph E. Turk, Jr., Garrett Casey
  • Publication number: 20230355852
    Abstract: The disclosed subject matter relates to extracorporeal blood processing or other processing of fluids. A blood treatment system treats blood with multiple fluids and performs fluid balancing on a patient's blood compartment. Multiple streams influence the patient temperature but only a subset of the fluids are dynamically temperature regulated. The system regulates a temperature of the flow, for example, of dialysate in order to regulate the return temperature of blood, in such a way that the temperature effect of the multiple streams is compensated.
    Type: Application
    Filed: July 20, 2023
    Publication date: November 9, 2023
    Applicant: NxStage Medical, Inc.
    Inventor: Dennis M. Treu
  • Publication number: 20230338635
    Abstract: Features for protecting against leaks in a fluid circuit are disclosed. In an embodiment, a first indicator of a leak is used to trigger confirmation by blood flow reversal and air detection in the blood circuit. A method for performing a blood treatment includes, at blood treatment machine, pumping blood to a patient through a first blood line. Further, at a controller of the blood treatment machine, a first signal is received, indicating a probability of a leak in the first blood line. Responsively to the first signal, the controller commands a leak verification operation and receives a second signal indicating whether a leak in the first blood line is verified. Further, a leak indicating signal is generated if the second signal indicates a leak is verified.
    Type: Application
    Filed: July 5, 2023
    Publication date: October 26, 2023
    Applicant: NxStage Medical, Inc.
    Inventors: Jeffrey H. Burbank, Dennis M. Treu, James M. Brugger, Daniel Joseph Rubery, JR.
  • Patent number: 11783939
    Abstract: An automatic monitoring system for a medical treatment device helps to ensure that an a medical treatment device operated at a treatment location away from a clinic is preformed safely. The monitoring system may verify that an assistant is present during treatment of the patient. Among the features disclosed biometric authentication to verify that a trained assistant is present, a presence detector to ensure the assistant is continuously present during treatment, and warning and recovery processes that allow intermittent lapses in the continuous presence of the assistant. The treatment device also communicates with a remote server or terminal.
    Type: Grant
    Filed: December 31, 2020
    Date of Patent: October 10, 2023
    Assignee: NxStage Medical, Inc.
    Inventors: Jeffrey H. Burbank, Dennis M. Treu, James M. Brugger