Abstract: A shell removal device includes a platform configured to secure a mold. An untrimmed shell is formed over the mold. The shell removal device further includes a drive mechanism configured to move the platform away from the untrimmed shell responsive to sensor data indicative that the untrimmed shell has begun to separate from the mold.

Abstract: Embodiments relate to automating removal of an untrimmed shell from a mold. In one embodiment, a shell removal device includes a body and a platform disposed within the body. The platform is configured to secure a mold that has an untrimmed shell formed over the mold. The shell removal device further includes a cover configured to secure the untrimmed shell to an upper surface of one or more sidewalls of the body and provide a seal between a lower surface of the untrimmed shell and the upper surface of the one or more sidewalls of the body. The shell removal device may include a media inlet in the body to permit pressurized media into the interior of the body to cause a pressure differential between an upper surface of the untrimmed shell and the lower surface of the untrimmed shell to cause the untrimmed shell to release from the mold.

Abstract: Embodiments relate to automating removal of an untrimmed shell from a mold. In one embodiment, a shell removal device includes a body and a platform disposed within the body. The platform is configured to secure a mold that has an untrimmed shell formed over the mold. The shell removal device further includes a cover configured to secure the untrimmed shell to an upper surface of one or more sidewalls of the body and provide a seal between a lower surface of the untrimmed shell and the upper surface of the one or more sidewalls of the body. The shell removal device may include a media inlet in the body to permit pressurized media into the interior of the body to cause a pressure differential between an upper surface of the untrimmed shell and the lower surface of the untrimmed shell to cause the untrimmed shell to release from the mold.

Abstract: A solid imaging apparatus is provided that includes a replaceable cartridge containing a source of build material and an extendable and retractable flexible transport film for transporting the build material layer-by-layer from the cartridge to the surface of a build in an image plane. An operator using the device needs merely to remove a spent cartridge and replace it with a fresh cartridge to continue solid imaging virtually uninterrupted. The apparatus also includes the capability of withdrawing and inserting an imager without the operator having to perform a separate alignment step. A brush attached to the transport film and forming part of the cartridge provides for intra-layer removal of excess uncured build material. If desired, the apparatus can produce a fully reacted build. A high intensity UV source cures the build between layers. An injection molded build pad is designed to hold a build in an inverted position for improving the build.

Abstract: A solid imaging apparatus and method employing a radiation transparent build material carrier and a build material dispensing system that accurately controls the thickness of the transferred layer of solidifiable liquid build material to the radiation transparent build material carrier to achieve high resolution imaging in three-dimensional objects built using an electro-optical radiation source.

Abstract: A disposable liquid build material feed cartridge for use in a solid imaging apparatus and a method of dispensing build material for use in such an apparatus with a radiation transparent build material carrier. The disposable liquid build material feed cartridge recovers unused liquid material from the radiation transparent build material carrier and recycles it through a filter into a supply reservoir for reuse. A dispersing roller is employed to express any entrapping air bubbles in the solidifiable liquid build material that is dispensed onto the radiation transparent build material carrier prior to its being imaged.

Abstract: A method and apparatus for making a foam-in-place cushion in which a foam-forming composition is dispensed between two plastic film portions in a predetermined fashion to selectively control the distribution of the foam in the cushion. A foam dispenser can be moved in a transverse direction as foam is dispensed. A dispersion device can be employed to apply pressure on predetermined areas of the film portions towards each other so as to cause the composition to be redistributed in position in a predetermined manner while the composition is in a less than fully expanded state. The plastic film can then be sealed closed to form an expanding foam cushion that can be placed into a shipping carton where the cushion expands to fill void space, or into a mold where the cushion expands and is molded into a desired shape.

Abstract: A toolholder for use in a metalworking operation, with a body extending along a longitudinal axis and a recess extending within the first end of the body. Adjacent an insert pocket adapted to receive a cutting insert in the recess is at least one wall with a portion having a surface with multiple interruptions to form a chip ejection segment. The chip ejection segment may be an integral part of the toolholder body or may be a discrete piece removably attached to the toolholder body. A method of imparting to a toolholder such a chip ejection segment is also disclosed.

Abstract: Described herein are antibacterial compounds, methods for making the compounds, pharmaceutical compositions containing the compounds and methods of treating bacterial infections utilizing the compounds and pharmaceutical composition.

Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.

Abstract: Disclosed are compounds of the formula wherein: W is NH, S, SO, or SO2; R2 is (un)substituted aryl, (un)substituted heteroaryl, or (un)substituted carbocycle or heterocycle; Q is hydrogen or lower alkyl; R4 and R6 are the same or different and represent hydrogen, halogen, lower alkyl, lower alkoxy, (un)substituted aryl, (un)substituted heteroaryl, (un)substituted arylalkyl or (un)substituted heteroarylalkyl; and R8 is hydrogen, lower alkyl or an (un)substituted carbocyclic group containing from 3-7 members, up to two of which members are optionally hetero atoms selected from oxygen and nitrogen; or R8 is (un)substituted aryl, (un)substituted heteroaryl, (un)substituted arylalkyl or (un)substituted heteroarylalkyl. These compounds are useful for treating cell proliferative disorders, such as cancer and restenosis. These compounds are potent inhibitors of cyclin-dependent kinases (cdks) and growth factor-mediated kinases.

Abstract: An apparatus and a method for inflating an inflatable web in which, in one embodiment, the inflatable web is conveyed along a path of travel with an inflation element positioned between unsealed edges of the web and proximate the inflation ports of the web's inflatable chambers, and a tracking sensor is used to detect the transverse position of the web with respect to the inflation element. A web tracking system is employed to continually adjust the transverse position of the web to maintain it within a predetermined range with respect to the inflation element. In this manner, the consistency of inflation of the inflatable chambers is improved.

Abstract: A solid imaging apparatus and method employing build material transfer means effective to transfer solidifiable liquid build material from a first side of a radiation transparent build material carrier to a receiving substrate without entrapping air bubbles in layers of transferred solidifiable liquid build material and to cleanly separate the solidified build material from the radiation transparent build material carrier as each layer is formed during the layerwise building of a three-dimensional object. An expandable membrane forming an arcuate dome and a reciprocatible flexible film are employed to effect transfer of the solidifiable liquid build material.

Abstract: A solid imaging apparatus and method employing sub-pixel shifting in multiple exposures of the digitally light projected image of a cross-section of a three-dimensional object on a solidifiable liquid medium. The multiple exposures provide increased resolution, preserving image features in a three-dimensional object and smoothing out rough or uneven edges that would otherwise be occur using digital light projectors that are limited by the number of pixels in an image projected over the size of the image. Algorithms are used to select pixels to be illuminated within the boundary of each image projected in the cross-section being exposed.

Abstract: The present invention provides substituted 2-aminopyridines of formula I, wherein R1, A1, W, X, and Y are as defined in the specification, useful in treating cell proliferative disorders. The novel compounds of the present invention are potent inhibitors of cyclin-dependent kinases 4 (Cdk4).