Patents by Inventor Dennis R. Berry

Dennis R. Berry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A87689 compounds
    Patent number: 5451403
    Abstract: Fermentation product A87689 is produced by a strain of Amycolatopsis mediterranei selected from NRRL 18815 and NRRL 18851, or an A87689-producing mutant thereof. A87689, its C.sub.1-6 -alkyl ether and C.sub.1-6 -alkanoyl ester derivatives and pharmaceutically acceptable salts thereof are phospholipase A.sub.2 inhibitors that are useful as antiinflammatory agents. Fermentation products known as BU-3889V, its components and pharmaceutically acceptable salts thereof, are phospholipase A.sub.2 inhibitors that are also useful as antiinflammatory agents.
    Type: Grant
    Filed: April 28, 1994
    Date of Patent: September 19, 1995
    Assignee: Eli Lilly and Company
    Inventors: Dennis R. Berry, Anne H. Dantzig, Manuel Debono, Robert Hamill, R. Michael Molloy, Raymond C. Yao
  • A87689 compounds employed as a phospholipase A.sub.2 (PLA.sub.2) inhibitor to treat inflammatory diseases
    Patent number: 5350579
    Abstract: Fermentation product A87689 is produced by a strain of Amycolatopsis mediterranei selected from NRRL 18815 and NRRL 18851, or an A87689-producing mutant thereof. A87689, its C.sub.1-6 -alkyl ether and C.sub.1-6 -alkanoyl ester derivatives and pharmaceutically acceptable salts thereof are phospholipase A.sub.2 inhibitors that are useful as antiinflammatory agents. Fermentation products known as BU-3889V, its components and pharmaceutically acceptable salts thereof, are phospholipase A.sub.2 inhibitors that are also useful as antiinflammatory agents.
    Type: Grant
    Filed: August 9, 1993
    Date of Patent: September 27, 1994
    Assignee: Eli Lilly and Company
    Inventors: Dennis R. Berry, Anne H. Dantzig, Manuel Debono, Robert Hamill, R. Michael Molloy, Raymond C. Yao
  • Amycolatopsis mediterranei strains useful to prepare A87689 compounds
    Patent number: 5278064
    Abstract: Fermentation product A87689 is produced by a strain of Amycolatopsis mediterranei selected from NRRL 18815 and NRRL 18851, or an A87689-producing mutant thereof. A87689, its C.sub.1-6 -alkyl ether and C.sub.1-6 -alkanoyl ester derivatives and pharmaceutically acceptable salts thereof are phospholipase A.sub.2 inhibitors that are useful as antiinflammatory agents. Fermentation products known as BU-3889V, its components and pharmaceutically acceptable salts thereof, are phospholipase A.sub.2 inhibitors that are also useful as antiinflammatory agents.
    Type: Grant
    Filed: May 4, 1992
    Date of Patent: January 11, 1994
    Assignee: Eli Lilly and Company
    Inventors: Dennis R. Berry, Anne H. Dantzig, Manuel Debono, Robert Hamill, R. Michael Molloy, Raymond C. Yao
  • Enzymatic deesterification of cephalosporin methyl esters
    Patent number: 4316955
    Abstract: The microorganism Streptomyces capillispira, NRRL 12279, produces an enzyme which deesterifies cephalosporin methyl esters.
    Type: Grant
    Filed: November 10, 1980
    Date of Patent: February 23, 1982
    Assignee: Eli Lilly and Company
    Inventors: Bernard J. Abbott, Dennis R. Berry