Patents by Inventor Dennis R. Burton

Dennis R. Burton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human neutralizing monoclonal antibodies to human immunodeficiency virus
    Patent number: 5652138
    Abstract: The present invention describes human monoclonal antibodies which immunoreact with and neutralize human immunodeficiency virus (HIV). Also disclosed are immunotherapeutic and diagnostic methods of using the monoclonal antibodies, as well as cell line for producing the monoclonal antibodies.
    Type: Grant
    Filed: July 18, 1994
    Date of Patent: July 29, 1997
    Assignee: The Scripps Research Institute
    Inventors: Dennis R. Burton, Carlos F. Barbas, Richard A. Lerner
  • Antibodies with altered effector functions
    Patent number: 5624821
    Abstract: An antibody with an altered function, e.g. altered affinity for an effector ligand such as Fc receptor (FcR) on a cell or the C1 component of complement is produced by replacing at least one amino acid residue in the constant portion of the antibody with a different residue.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 29, 1997
    Assignee: Scotgen Biopharmaceuticals Incorporated
    Inventors: Gregory P. Winter, Alexander R. Duncan, Dennis R. Burton