Patents by Inventor Dennis ROOP

Dennis ROOP has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF GENERATING XENOCHIMAERIC MICE WITH TUMOR AND HEMATOPOIETIC SYSTEM FROM THE SAME HETEROLOGOUS SPECIES
    Publication number: 20140109246
    Abstract: The present invention provides methods for the generation of xenochimaeric animals; for example, xenochimaeric mice, comprising bone marrow progenitor cells and tumors from a heterologous animal. In some aspects, the invention provides xenochimaeric mice bearing humanized bone marrow and human tumors. Such animals are a model system for the study of human tumor stroma, for drug discovery, and for the treatment of human cancers.
    Type: Application
    Filed: September 24, 2013
    Publication date: April 17, 2014
    Applicant: The Regents of the University of Colorado, a body corporate
    Inventors: Antonio JIMENO, Yosef REFAELI, Xiao-Jing WANG, Dennis ROOP