Abstract: The present disclosure relates to methods for generating broadly neutralizing bovine anti-HIV Env antibodies, compositions comprising the broadly neutralizing bovine antibodies, and methods of treatment or prevention of HIV using the broadly neutralizing bovine antibodies. In certain embodiments, a broadly neutralizing bovine antibody comprises a polyclonal F(ab) or F(ab?)2 fragment. In certain embodiments, a broadly neutralizing bovine antibody comprises a humanized bovine monoclonal antibody.

Abstract: The present invention provides HIV-1 vaccine immunogens. Some of the immunogens contain a soluble gp140-derived protein that harbors a modified N-terminus of the HR1 region in gp41. Some of the immunogens contain an HIV-1 Env-derived trimer protein that is presented on a nanoparticle platform. The invention also provides methods of using the HIV-1 vaccine immunogens for eliciting an immune response or treating HIV infections.

Abstract: A cam assembly for a compound archery bow includes a cam adjustable component. The cam adjustable component is operable to move with respect to the base by rotating a drive mechanism. The cam adjustable component may be a draw module, cable stop, and/or limb stop. When the cam adjustable component is the draw module, the cable stop and/or limb stop may be operatively connected to the draw module such that movement of the draw module simultaneously moves the cable stop and/or limb stop.

Abstract: This invention relates generally to uses of novel nanomaterial composition and the systems in which they are used, and more particularly to nanomaterial compositions generally comprising carbon and a metal, which composition can be exposed to pulsed emissions to react, activate, combine, or sinter the nanomaterial composition. The nanomaterial compositions can alternatively be utilized at ambient temperature or under other means to cause such reaction, activation, combination, or sintering to occur.

Abstract: This invention relates generally to uses of novel nanomaterial composition and the systems in which they are used, and more particularly to nanomaterial compositions generally comprising carbon and a metal, which composition can be exposed to pulsed emissions to react, activate, combine, or sinter the nanomaterial composition. The nanomaterial compositions can alternatively be utilized at ambient temperature or under other means to cause such reaction, activation, combination, or sintering to occur.

Abstract: This invention relates generally to uses of novel nanomaterial composition and the systems in which they are used, and more particularly to nanomaterial compositions generally comprising carbon and a metal, which composition can be exposed to pulsed emissions to react, activate, combine, or sinter the nanomaterial composition. The nanomaterial compositions can alternatively be utilized at ambient temperature or under other means to cause such reaction, activation, combination, or sintering to occur.

Abstract: This invention relates generally to uses of novel nanomaterial composition and the systems in which they are used, and more particularly to nanomaterial compositions generally comprising carbon and a metal, which composition can be exposed to pulsed emissions to react, activate, combine, or sinter the nanomaterial composition. The nanomaterial compositions can alternatively be utilized at ambient temperature or under other means to cause such reaction, activation, combination, or sintering to occur.

Abstract: An apparatus for neutralizing an explosive comprises a housing including at least one relief groove along an outer portion of the housing, and an inner chamber. The inner chamber includes a first hollow section and a second hollow section. The cross-sectional area of the second hollow section is smaller than the cross-sectional area of the first hollow section. A forward section of the housing is adapted to receive a first nose member and a rear section of the housing is adapted to receive a removable fin set.

Abstract: This invention relates generally to uses of novel nanomaterial composition and the systems in which they are used, and more particularly to nanomaterial compositions generally comprising carbon and a metal, which composition can be exposed to pulsed emissions to react, activate, combine, or sinter the nanomaterial composition. The nanomaterial compositions can alternatively be utilized at ambient temperature or under other means to cause such reaction, activation, combination, or sintering to occur.

Abstract: This invention relates generally to uses of novel nanomaterial composition and the systems in which they are used, and more particularly to nanomaterial compositions generally comprising carbon and a metal, which composition can be exposed to pulsed emissions to react, activate, combine, or sinter the nanomaterial composition. The nanomaterial compositions can alternatively be utilized at ambient temperature or under other means to cause such reaction, activation, combination, or sintering to occur.

Abstract: A system and method that provides suppliers or sellers with a competitive opportunity to influence consumers at the precise moment a purchasing decision is being made. A consumer using a personal wireless device (110), which has an integrated bar code scanner (120), scans the bar code of a product in a store. The device, using wireless communication (420), sends the scanned product information and a consumer ID to a processing application (430). The processing application (430) sends a profile of the consumer's past shopping behavior, the scanned product information and other data to each interested supplier's competitive incentive offer engine (470). Each supplier's incentive engine determines the optimal incentive to offer and returns this data to the processing application (430) where the incentives are collectively sent back to the consumer's device (110) using wireless communication (421).

Abstract: The invention is directed to improvement in thermal covers used to protect piping, liquid transmission, backflow prevention systems, etc. The improved thermal cover includes an insulated pad, a heat barrier and wrapper to hold the insulated pad configured in a specific fashion so as to improve freezing resistance and/or reduction of damage due to excessive heat. Padlocks, ties, etc. secure a thermal cover by means of grommets to an underlying piping, liquid transmission, backflow prevention system, etc. component. Removal of a tie permits access to the underlying components. Padlocks provide security for the thermal cover simultaneously with the access afforded due to removal of a tie. One or more foil layers further enhance protection against radiant heat loss. The combination of the one or more components of foil backing attached to structurally strong foam contributes to the thermal cover's ability to maintain its shape and it's effectiveness over time.

Abstract: A system and method that provides suppliers or sellers with a competitive opportunity to influence consumers at the precise moment a purchasing decision is being made. A consumer using a personal wireless device (110), which has an integrated bar code scanner (120), scans the bar code of a product in a store. The device, using wireless communication (420), sends the scanned product information and a consumer ID to a processing application (430). The processing application (430) sends a profile of the consumer's past shopping behavior, the scanned product information and other data to each interested supplier's competitive incentive offer engine (470). Each supplier's incentive engine determines the optimal incentive to offer and returns this data to the processing application (430) where the incentives are collectively sent back to the consumer's device (110) using wireless communication (421).

Abstract: This invention generally relates to a method and apparatus to neutralize ordnance, more specifically improvised explosive devices (IEDs) and unexploded ordnance (UXOs). The current invention provides a simple method to neutralize the ordnance by taking advantage of a new class of energetic materials that includes nano-thermites, binary thermites and additionally powdered thermites. In the invention, a projectile is loaded with the new class of energetic materials and fired into the ordnance. The impact causes the energetic materials to react in such a fashion that the explosive compound or other material within the IED or UXO is burned in a self-propagating mode without exploding. Hence, the ordnance is neutralized.

Abstract: This invention relates generally to uses of novel nanomaterial composition and the systems in which they are used, and more particularly to nanomaterial compositions generally comprising carbon and a metal, which composition can be exposed to pulsed emissions to react, activate, combine, or sinter the nanomaterial composition. The nanomaterial compositions can alternatively be utilized at ambient temperature or under other means to cause such reaction, activation, combination, or sintering to occur.

Abstract: An apparatus incorporating a chemical seal and method for removing fluids from a well is disclosed. The chemical seal is created by a foaming agent which, when in the presence of gas and fluids present in the well, and when agitated by the apparatus, creates foam between the apparatus and the walls of the well in which it operates. The foam improves the seal between the apparatus and the inner wall of the well, improving the efficiency of the apparatus in lifting fluids from the well. Furthermore, the chemical seal improves the distribution of treatment chemicals within the well as it reduces liquid flowback. Automatic recharging or reapplication of the foaming agent and/or treatment chemicals to the apparatus can be accomplished with a chemical application assembly associated with the well.

Abstract: Films having a structured surface with an engineered feature, such as prism grooves, to be used in displays having a backlight. The films can be arranged in a stack having one or more of the following: birefringent brightness enhancement films, non-birefringent brightness enhancement films, polarizers, diffusers, birefringent turning films, and non-birefringent turning films. Those films can be arranged in any order from the backlight to a viewer.

Abstract: A direct pour metal casting process and casting mold having a direct pour passage. The casting mold is filled from a bottom pour ladle that dispenses molten metal into a riser core. The riser core defines an opening that progresses from a circular opening in the top to a slot opening in the bottom of the riser core that is generally shaped as an inverted funnel.

Abstract: An improved gutter bracket assembly attached to exposed rafters for supporting a gutter provides increased strength as well as flexibility in attaching to various types of rafters by including a pair of flanges that attach to lateral sides of a rafter. Thereby, greater attachment strength is achieved than typical at the open grain of the rafter end. Attachable front and back clips provide secure attachment after initial placement of the gutter is made.