Patents by Inventor Dennis Wolan

Dennis Wolan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACOLOGICAL INHIBITORS OF THE ENL YEATS DOMAIN
    Publication number: 20220274980
    Abstract: Provided herein are compounds, pharmaceutical compositions, and methods for inhibiting the ENL YEATS domain. Further, provided herein are compounds, pharmaceutical compositions, and methods for the treatment of leukemia.
    Type: Application
    Filed: July 29, 2020
    Publication date: September 1, 2022
    Inventors: Michael A. Erb, Dennis Wolan, Seiya Kitamura, Arnab Chatterjee
  • METHODS FOR IDENTIFYING NOVEL ANTIBIOTICS AND RELATED COMPOSITIONS
    Publication number: 20190144912
    Abstract: This invention provides purified and recombinantly-produced bacterial lipoprotein signal peptidase (Lsp) enzymes and in vitro assays for monitoring Lsp catalytic activities. Also provided in the invention are screening methods for identifying novel antibiotic agents and their therapeutic applications for treating bacterial infections. Further provided in the invention are specific Lsp inhibitory compounds which can be used as bactericidal agents in treating diseases caused by bacterial infections.
    Type: Application
    Filed: September 1, 2016
    Publication date: May 16, 2019
    Inventors: Dennis Wolan, Anna Owensby
  • Activators of executioner procaspases 3, 6 and 7
    Patent number: 8642788
    Abstract: The present invention provides compounds as activators of procaspases 3, 6 and/or 7 and related derivatives, pharmaceutical compositions thereof, methods for their use, and methods for preparing these compounds. In one aspect, the compounds are useful for treating cancers and neoplastic diseases.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: February 4, 2014
    Assignee: The Regents of the University of California
    Inventors: Jim Wells, Adam R. Renslo, Dennis Wolan, Julie Zorn
  • ACTIVATORS OF EXECUTIONER PROCASPASES 3, 6 AND 7
    Publication number: 20110021522
    Abstract: The present invention provides compounds as activators of procaspases 3, 6 and/or 7 and related derivatives, pharmaceutical compositions thereof, methods for their use, and methods for preparing these compounds. In one aspect, the compounds are useful for treating cancers and neoplastic diseases.
    Type: Application
    Filed: January 9, 2009
    Publication date: January 27, 2011
    Applicant: The Regents of the University of California
    Inventors: Jim Wells, Adam R. Renslo, Dennis Wolan, Julie Zorn