Abstract: Wound closure devices and related methods. In one example, a wound closure device includes a release liner and several wound closure meshes held in a removable fashion to the release liner. The release liner includes a main body and several tabs, with the tabs secured in a detachable fashion to the main body. Each wound closure mesh is held in a removable fashion to the main body of the release liner and at least one of the tabs, with the tab including a portion that extends outwardly from an outer perimeter of the mesh to which it is held.

Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.