Abstract: The present invention provides a dressing for application onto a wound. The dressing comprises a porous mesh having a wound-facing side coated with an adhesive for adhering the porous mesh to the skin. The porous mesh is also configured for application of a polymerizable adhesive such that after application the polymerized adhesive and the porous mesh together form a barrier covering the wound. The dressing also includes an absorbent patch disposed on the wound-facing side of the porous mesh and arranged to overlie the wound during use.

Abstract: The present invention relates to: an antibody targeting a mutation of KRAS, which is an intracellular tumor-inducing protein, or a fusion protein in which a cancer-cell-penetrating peptide is connected, by means of a gene expression method or a chemical bonding method, to a single strand variable fragment of the antibody; and a tumor treatment use thereof. The fusion protein thus produced has the benefit of maximizing the anti-tumor or anti-cancer effect of the antibody targeting an intracellular tumor-inducing protein or a tumor-inducing mutant protein, or the single strand variable fragment of the antibody, by effectively invading a tumor cell.

Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions, wherein the compounds are generally of the Formulae The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ÿ-methyl carbapenems which are useful as antibacterial agents.

Abstract: The present invention provides ?-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment. The present invention is also in the field of synthetic organic chemistry and is specifically provides an improved method of synthesis of ?-methyl carbapenems which are useful as antibacterial agents.

Abstract: The present invention provides an anaerobic curing composition comprising a monofunctional or multifunctional acrylate or methacrylate as a polymerizable monomer having at least one functional vinyl group, 0.1 to 10 percent by weight of an organic peroxide and 0.1 to 10 percent by weight of at least one aromatic amine having a pKa of 6.5 to 9.0, based on the total weight of the monomer, which may be stored as a liquid for a long time and cures rapidly at anaerobic conditions, to form a strong bond between adjacent surfaces of, especially, metals, so that it is useful as an adhesive and sealant for metals.