Patents by Inventor Deok Kun Oh
Deok Kun Oh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20190233868Abstract: Disclosed are a composition for production of ginsenoside compound K using a high temperature-?-glycosidase and a high temperature-?-L-arabinofuranosidase, and a method for preparing ginsenoside compound k. The composition for producing ginsenoside compound k and the method for preparing ginsenoside compound k according to one aspect of the present invention allow high temperature-?glycosidase and high temperature-a-L-arabinofuranosidase to exhibit stable activity even at high temperatures, thereby increasing a reaction rate. The composition for producing ginsenoside compound k and the method for preparing ginsenoside compound k according to one aspect of the present invention allow a large quantity of ginsenoside compound k to be produced in a short time, thereby exhibiting an effect of producing a high yield, and thus can be utilized industrially.Type: ApplicationFiled: September 28, 2017Publication date: August 1, 2019Inventors: Junseong PARK, Kyeonghwan HWANG, Deok-Kun OH, Kyung-Chul SHIN
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Patent number: 9988618Abstract: The present invention provides a novel psicose epimerase derived from Flavonifractor plautii and capable of converting fructose to psicose. The novel psicose epimerase according to the present invention possesses an activity producing psicose by epimerizing the carbon-3 position of fructose, and has maximal activity for the conversion of fructose to psicose at a relatively high temperature and a pH less than or equal to neutral, has excellent thermal stability, and can mass-produce psicose from fructose in a high yield for a short amount of time. Therefore, the psicose epimerase according to the present invention is advantageous in the industrial production of psicose, and it is expected that the psicose produced thereby can be usefully utilized in the functional sugar industry and also as materials for health food, medicine, cosmetics, and the like using the psicose.Type: GrantFiled: May 22, 2015Date of Patent: June 5, 2018Assignee: DAESANG CORPORATIONInventors: Tae Gyun Kim, Min Su Kim, Tae Yong Kim, Eun Bum Song, Deok Kun Oh
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Patent number: 9914919Abstract: This disclosure relates to aldolase, an aldolase mutant, and a method and a composition for producing tagatose by using the same. The feature of the disclosure is environment-friendly due to the use of an enzyme acquired from microorganisms, requires only a simple process of enzyme immobilization, uses a low-cost substrate in a substrate compared with a conventional method for producing tagatose and has a remarkably high yield, thereby greatly reducing production costs and maximizing production effects.Type: GrantFiled: July 25, 2014Date of Patent: March 13, 2018Assignee: SAMYANG CORPORATIONInventors: Deok-Kun Oh, Seung-Hye Hong, Seon-Hwa Lee
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Publication number: 20180023073Abstract: There are provided aldolase, an aldolase mutant, a method for producing tagatose, and a composition for producing tagatose using the same. The technical feature of the present invention is environment-friendly due to the use of an enzyme acquired from microorganisms, requires only a simple process of enzyme-immobilization, uses a low-cost substrate compared with that of a conventional method for producing tagatose, and has a remarkably high yield, thereby greatly reducing production cost while maximizing production effect.Type: ApplicationFiled: September 28, 2017Publication date: January 25, 2018Inventors: Deok-Kun OH, Seung-Hye Hong, Seon-Hwa Lee
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Publication number: 20170101637Abstract: The present invention provides a novel psicose epimerase derived from Flavonifractor plautii and capable of converting fructose to psicose. The novel psicose epimerase according to the present invention possesses an activity producing psicose by epimerizing the carbon-3 position of fructose, and has maximal activity for the conversion of fructose to psicose at a relatively high temperature and a pH less than or equal to neutral, has excellent thermal stability, and can mass-produce psicose from fructose in a high yield for a short amount of time. Therefore, the psicose epimerase according to the present invention is advantageous in the industrial production of psicose, and it is expected that the psicose produced thereby can be usefully utilized in the functional sugar industry and also as materials for health food, medicine, cosmetics, and the like using the psicose.Type: ApplicationFiled: May 22, 2015Publication date: April 13, 2017Inventors: Tae Gyun KIM, Min Su KIM, Tae Yong KIM, Eun Bum SONG, Deok Kun OH
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Publication number: 20160186162Abstract: This disclosure relates to aldolase, an aldolase mutant, and a method and a composition for producing tagatose by using the same. The feature of the disclosure is environment-friendly due to the use of an enzyme acquired from microorganisms, requires only a simple process of enzyme immobilization, uses a low-cost substrate in a substrate compared with a conventional method for producing tagatose and has a remarkably high yield, thereby greatly reducing production costs and maximizing production effects.Type: ApplicationFiled: July 25, 2014Publication date: June 30, 2016Inventors: Deok-Kun Oh, Seung-Hye Hong, Seon-Hwa Lee
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Patent number: 9217166Abstract: The present invention relates to a D-psicose 3-epimerase variant with improved thermostability by substituting an amino acid at a specific position of an amino acid sequence of a wild type D-psicose 3-epimerase. Further, the present invention provides a recombinant expression vector including a gene of the D-psicose 3-epimerase variant, and a recombinant strain transformed with the recombinant expression vector. Furthermore, the present invention provides an immobilized reactor prepared using the D-psicose 3-epimerase variant or the recombinant strain, and a method of continuously producing D-psicose using the immobilized reactor.Type: GrantFiled: August 21, 2012Date of Patent: December 22, 2015Assignee: CJ CHEILJEDANG CORPORATIONInventors: Yang Hee Kim, Jin Ha Kim, Young Mi Lee, Young Ho Hong, Min Hae Kim, Seong Bo Kim, Seung Won Park, Seung Hyun Oh, Deok Kun Oh, Jin Geun Choi
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Publication number: 20140199732Abstract: The present invention relates to a D-psicose 3-epimerase variant with improved thermostability by substituting an amino acid at a specific position of an amino acid sequence of a wild type D-psicose 3-epimerase. Further, the present invention provides a recombinant expression vector including a gene of the D-psicose 3-epimerase variant, and a recombinant strain transformed with the recombinant expression vector. Furthermore, the present invention provides an immobilized reactor prepared using the D-psicose 3-epimerase variant or the recombinant strain, and a method of continuously producing D-psicose using the immobilized reactor.Type: ApplicationFiled: August 21, 2012Publication date: July 17, 2014Applicant: CJ CHEILJEDANG CORPORATIONInventors: Yang Hee Kim, Jin Ha Kim, Young Mi Lee, Young Ho Hong, Min Hae Kim, Seong Bo Kim, Seung Won Park, Seung Hyun Oh, Deok Kun Oh, Jin Geun Choi
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Patent number: 8609391Abstract: New mannose-6-phasphate isomerase, mutant enzyme thereof, and a method of producing L-ribose using the enzyme are provided, and more specifically, mannose-6-phosphate isomerase, mutant enzyme thereof, recombinant expression vectors including relevant genes, microorganisms transformed with the vectors, a method of producing mannose-6-phosphate isomerase or mutant thereof in bulk using them, and a high yield method of producing L-ribose using the mannose-6-isomerase or the mutant thereof, are provided.Type: GrantFiled: October 22, 2010Date of Patent: December 17, 2013Assignee: Konkuk University Industrial Cooperation Corp.Inventors: Deok Kun Oh, Soo Jin Yeom
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Patent number: 8481720Abstract: The present invention relates to a manufacturing method of tagatose using galactose isomerization of high yield, more particularly a method to enhance conversion rate of isomerization by adding borate which binds specifically to tagatose and a manufacturing method of tagatose using the same.Type: GrantFiled: December 10, 2007Date of Patent: July 9, 2013Assignee: CJ Cheiljedang CorporationInventors: Seong-bo Kim, Seung-won Park, Sang-hoon Song, Kang-pyo Lee, Deok-kun Oh, Byoung-chul Lim, Hye-jung Kim
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Publication number: 20120270274Abstract: New mannose-6-phasphate isomerase, mutant enzyme thereof, and a method of producing L-ribose using the enzyme are provided, and more specifically, mannose-6-phosphate isomerase, mutant enzyme thereof, recombinant expression vectors including relevant genes, microorganisms transformed with the vectors, a method of producing mannose-6-phosphate isomerase or mutant thereof in bulk using them, and a high yield method of producing L-ribose using the mannose-6-isomerase or the mutant thereof, are provided.Type: ApplicationFiled: October 22, 2010Publication date: October 25, 2012Applicant: Konkuk University Industrial Cooperation Corp.Inventors: Deok Kun Oh, Soo Jin Yeom
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Patent number: 8030035Abstract: Provided is a method of producing D-psicose using a D-psicose epimerase derived from Agrobacterium tumefaciens. Provided are a protein having an amino acid sequence of SEQ ID NO:1 and having a psicose 3-epimerase activity, a gene encoding the protein, a recombinant expression vector containing the gene, and a method of producing D-psicose by reacting the protein produced on a mass scale with D-fructose. The method of producing D-psicose is an environmentally friendly method using a new enzyme, in which an inexpensive substrate is used, and the activity of the enzyme can be retained for a prolonged time period. Thus, the method can be efficiently used for the mass production of D-psicose.Type: GrantFiled: May 30, 2006Date of Patent: October 4, 2011Assignee: CJ Cheiljedang Corp.Inventors: Deok-Kun Oh, Hye-Jung Kim, Yong-Joo Lee, Sang-Hoon Song, Seung-Won Park, Jung-Hoon Kim, Seong-Bo Kim
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Patent number: 7846702Abstract: Provided is a process for continuously producing xylitol in high yield and productivity using a vacuum microfiltration bioreactor containing a fermentation medium for a strain of the genus Candida, which includes: 5 300 g/l of xylose, 1 10 g/l of urea, 1 10 g/l of potassium diphosphate, 0.01 1 g/l of magnesium sulfate, 0.1-10 mg/l of MnSO404H2O, 0.1 10 mg/l of CoCl2-6H2O, 0.1 10 mg/l of NaMoO4-2H2O, 0.1 10 mg/l of ZnSO4-7H2O, 0.1 10 mg/l of AlCl3-6H2O, 0.1 10 mg/l of CuCl2-2H2O, 0.01-5 mg/l of H3BO3, 1-100 mg/l of FeSO4 7H2O, 0.1-10 mg/l of ascorbic acid, 1-100 mg/l of biotin, 1-100 mg of choline, 1-200 mg/l of folic acid, 1-100 mg/l of inositol, 1-100 mg/l of nicotinic acid, 0.1-10 mg/l of p-aminobezoic acid, 1-100 mg/l of pantothernic acid, 0.1-10 mg/l of pyridoxine, 10-1,000 mg/l of riboflavin, and 1-100 mg/l of thiamine.Type: GrantFiled: August 8, 2008Date of Patent: December 7, 2010Assignee: CJ Cheiljedang CorporationInventors: Deok-kun Oh, Taek-bum Kim, Jung-hoon Kim, Seong-bo Kim, Seung-won Park, Soon-chul Kim
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Publication number: 20100190225Abstract: Provided is a method of producing D-psicose using a D-psicose epimerase derived from Agrobacterium tumefaciens. Provided are a protein having an amino acid sequence of SEQ ID NO:1 and having a psicose 3-epimerase activity, a gene encoding the protein, a recombinant expression vector containing the gene, and a method of producing D-psicose by reacting the protein produced on a mass scale with D-fructose. The method of producing D-psicose is an environmentally friendly method using a new enzyme, in which an inexpensive substrate is used, and the activity of the enzyme can be retained for a prolonged time period. Thus, the method can be efficiently used for the mass production of D-psicose.Type: ApplicationFiled: May 30, 2006Publication date: July 29, 2010Applicant: CJ CHEILJEDANG CORP.Inventors: Deok-Kun Oh, Hye-Jung Kim, Yong-Joo Lee, Sang-Hoon Song, Seung-Won Park, Jung-Hoon Kim, Seong-Bo Kim
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Publication number: 20090306366Abstract: The present invention relates to a manufacturing method of tagatose using galactose isomerization of high yield, more particularly a method to enhance conversion rate of isomerization by adding borate which binds specifically to tagatose and a manufacturing method of tagatose using the same.Type: ApplicationFiled: December 10, 2007Publication date: December 10, 2009Applicant: CJ CHEILJEDANG CORPORATIONInventors: Seong-bo Kim, Seung-won Park, Sang-hoon Song, Kang-pyo Lee, Deok-kun Oh, Byoung-chul Lim, Hye-jung Kim
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Publication number: 20090197313Abstract: Provided is a process for continuously producing xylitol in high yield and productivity using a vacuum microfiltration bioreactor containing a fermentation medium for a strain of the genus Candida, which includes: 5 300 g/l of xylose, 1 10 g/l of urea, 1 10 g/l of potassium diphosphate, 0.01 1 g/l of magnesium sulfate, 0.1-10 mg/1 of MnSO404H2O, 0.1 10 mg/1 of CoCl2-6H2O, 0.1 10 mg/1 of NaMoO4-2H2O, 0.1 10 mg/1 of ZnSO4-7H2O, 0.1 10 mg/1 of AlCl3-6H2O, 0.1 10 mg/1 of CuCl2-2H2O, 0.01-5 mg/1 of H3BO3, 1-100 mg/1 of FeSO4 7H2O, 0.1-10 mg/1 of ascorbic acid, 1-100 mg/1 of biotin, 1-100 mg of choline, 1-200 mg/1 of folic acid, 1-100 mg/1 of inositol, 1-100 mg/1 of nicotinic acid, 0.1-10 mg/1 of p-aminobezoic acid, 1-100 mg/1 of pantothernic acid, 0.1-10 mg/1 of pyridoxine, 10-1,000 mg/1 of riboflavin, and 1-100 mg/1 of thiamine.Type: ApplicationFiled: August 8, 2008Publication date: August 6, 2009Applicant: CJ CheilJedang CorporationInventors: Deok-kun Oh, Taek-bum Kim, Jung-hoon Kim, Seong-bo Kim, Seung-won Park, Soon-chul Kim
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Patent number: 7427500Abstract: Provided is a process for continuously producing xylitol in high yield and productivity using a vacuum microfiltration bioreactor containing a fermentation medium for a strain of the genus Candida, which includes: 5 300 g/l of xylose, 1 10 g/l of urea, 1 10 g/l of potassium diphosphate, 0.01 1 g/l of magnesium sulfate, 0.1-10 mg/l of MnSO4.4H2O, 0.1 10 mg/l of CoCl2.6H2O, 0.1 10 mg/l of NaMoO4.2H2O, 0.1 10 mg/l of ZnSO4.7H2O, 0.1 10 mg/l of AlCl3.6H2O, 0.1 10 mg/l of CuCl2.2H2O, 0.01-5 mg/l of H3BO3, 1-100 mg/l of FeSO4 7H2O, 0.1-10 mg/l of ascorbic acid, 1-100 mg/l of biotin, 1-100 mg of choline, 1-200 mg/l of folic acid, 1-100 mg/l of inositol, 1-100 mg/l of nicotinic acid, 0.1-10 mg/l of p-aminobezoic acid, 1-100 mg/l of pantothenic acid, 0.1-10 mg/l of pyridoxine, 10-1,000 mg/l of riboflavin, and 1-100 mg/l of thiamine.Type: GrantFiled: November 22, 2004Date of Patent: September 23, 2008Assignee: CJ CheilJedang CorporationInventors: Deok-kun Oh, Taek-bum Kim, Jung-hoon Kim, Seong-bo Kim, Seung-won Park, Soon-chul Kim
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Publication number: 20070117194Abstract: Provided is a process for continuously producing xylitol in high yield and productivity using a vacuum microfiltration bioreactor containing a fermentation medium for a strain of the genus Candida, which includes: 5 300 g/l of xylose, 1 10 g/l of urea, 1 10 g/l of potassium diphosphate, 0.01 1 g/l of magnesium sulfate, 0.1-10 mg/l of MnSO4.4H2O, 0.1 10 mg/l of CoCl2.6H2O, 0.1 10 mg/l of NaMoO4.2H2O, 0.1 10 mg/l of ZnSO4.7H2O, 0.1 10 mg/l of AlCl3.6H2O, 0.1 10 mg/l of CuCl2.2H2O, 0.01-5 mg/l of H3BO3, 1-100 mg/l of FeSO4 7H2O, 0.1-10 mg/l of ascorbic acid, 1-100 mg/l of biotin, 1-100 mg of choline, 1-200 mg/l of folic acid, 1-100 mg/l of inositol, 1-100 mg/l of nicotinic acid, 0.1-10 mg/l of p-aminobezoic acid, 1-100 mg/l of pantothenic acid, 0.1-10 mg/l of pyridoxine, 10-1,000 mg/l of riboflavin, and 1-100 mg/l of thiamine.Type: ApplicationFiled: November 22, 2004Publication date: May 24, 2007Inventors: Deok-kun Oh, Taek-bum Kim, Jung-hoon Kim, Seong-bo Kim, Seung-won Park, Soon-chul Kim
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Patent number: 7166744Abstract: The present invention relates to a novel retinoid derivative compound represented by the formula I: wherein X, R1, R2 and R3 are as defined herein or pharmaceutically acceptalbe salts thereof. Also, the present invention relates to processes for producing the compound of the formula I and to an anti-cancer composition comprising the compound of the formula I. The compound of the formula I according to the present invention exerts high anti-cancer effects while not causing undesirable side effects.Type: GrantFiled: May 29, 2002Date of Patent: January 23, 2007Assignee: Chebigen Co., Ltd.Inventors: Hong-Sig Sin, Soo-Jong Um, Young-Soy Rho, Si-Ho Park, Youn-Ja Kwon, Myoung-Soon Park, Hye-Sook Han, So-Mi Kim, Dong-Myoung Kim, Deok-Kun Oh, Jong-Sup Park, Tae-Sung Bae
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Patent number: 7030265Abstract: The present invention relates to novel retinol derivatives, the methods of preparation and the uses thereof. According to the present invention, retinol derivatives comprise carboester linkage between di-, tri-, polypeptide having functional group of COOH and retinol. Retinol derivatives in the present invention comprise carboester linkage between amino acid having functional group of di-COOH and retinol. Retinol derivatives comprise carboester linkage between retinol and the compounds having the function group of COOH and multiple double bonds on carbon chain. Retinol derivatives in the present invention comprise carboester linkage between retinol and the compounds having the functional group of di-COOH and one double bond. Retinol derivatives in the present invention comprise ether linkage between the compounds with OH functional group and retinol.Type: GrantFiled: January 10, 2002Date of Patent: April 18, 2006Assignee: Chebigen, Inc.Inventors: Hong-Sig Sin, Si-Ho Park, Young-Soy Rho, Soo-Jong Um, Youn-Ja Kwon, Myoung-Soon Park, Hye-Sook Han, Min-Sook Jung, So-Mi Kim-Cho, Dong-Myong Kim, Deok-kun Oh, Jong-Sup Park