Patents by Inventor De Qian Wang

De Qian Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT FACTOR VIII FORMULATIONS
    Publication number: 20160030524
    Abstract: Provided are liquid and lyophilized recombinant Factor VIII formulations, including formulations for polymer-conjugated FVIII such as PEGylated Factor VIII.
    Type: Application
    Filed: March 11, 2014
    Publication date: February 4, 2016
    Applicant: BAYER HEALTHCARE LLC
    Inventors: De Qian WANG, Xinghang MA, Nelly TSVETKOVA
  • Cryopreservation bag assembly for mammalian cell lines
    Patent number: 6670175
    Abstract: The invention is a novel cell freezing and storage bag assembly and method for using the assembly in the seed train expansion of mammalian cells. The bag is constructed principally of polytetrafluoroethylene fabric. The bag is designed to hold enough cells that a bioreactor can be inoculated directly. The bag is designed to be filled to a fraction of its maximum capacity so that the cell suspension has a very thin cross-section (less than about 10 millimeters). The bag design includes a transfer set that can be sterilely welded to the source of the mammalian cells. This sterile-weldable transfer set allows the bags to be filled quickly with minimal risk of contamination. In the method, once each bag is filled, it is sealed below the connection with the transfer set and the bag is cut “above” the new seal (on the same side of the seal as the transfer set). When a bioreactor is to be inoculated, the contents of the bag are drained via a sterile-weldable inoculation line.
    Type: Grant
    Filed: May 9, 2002
    Date of Patent: December 30, 2003
    Assignee: Bayer Pharmaceuticals Corporation
    Inventors: De Qian Wang, Bruce Gardner, Rudiger Heidemann, Mokhtar Mered, William H. Kelsey
  • Cryopreservation bag assembly for mammalian cell lines
    Publication number: 20020168759
    Abstract: The invention is a novel cell freezing and storage bag assembly and method for using the assembly in the seed train expansion of mammalian cells. The bag is constructed principally of polytetrafluoroethylene fabric. The bag is designed to hold enough cells that a bioreactor can be inoculated directly. The bag is designed to be filled to a fraction of its maximum capacity so that the cell suspension has a very thin cross-section (less than about 10 millimeters). The bag design includes a transfer set that can be sterilely welded to the source of the mammalian cells. This sterile-weldable transfer set allows the bags to be filled quickly with minimal risk of contamination. In the method, once each bag is filled, it is sealed below the connection with the transfer set and the bag is cut “above” the new seal (on the same side of the seal as the transfer set). When a bioreactor is to be inoculated, the contents of the bag are drained via a sterile-weldable inoculation line.
    Type: Application
    Filed: May 9, 2002
    Publication date: November 14, 2002
    Inventors: De Qian Wang, Bruce Gardner, Rudiger Heidemann, Mokhtar Mered, William H. Kelsey