Patents by Inventor Dequan Dou

Dequan Dou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STAT3 and ERK signal pathway inhibitor comprising mogrosides and analogs thereof
    Patent number: 10617734
    Abstract: The present invention relates to a chemical and pharmaceutical technology, and in particular to a STAT3 and ERK signal pathway inhibitor and a use thereof. The present invention provides a STAT3 and ERK signal pathway inhibitor. The inhibitor mainly consists of a mogroside and/or an analog thereof. The mogroside and the analog thereof inhibit the phosphorylation of a transcription factor STAT3 and the phosphorylation of an ERK. The method for preparing the mogroside and the analog has the characteristics of simpleness, strong operability and high purity of products. The present invention further provides a use of the STAT3 and ERK signal pathway inhibitor in the preparation of drugs for treating tumors, which realizes the purposes of inhibiting the proliferation of cancer cells and promoting the apoptosis of cancer cells and has a very good inhibition effect on cancers.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: April 14, 2020
    Assignee: BEIJING UNIVERSITY OF AGRICULTURE
    Inventors: Can Liu, Lanqing Ma, Dequan Dou, Yuanxia Sun, Long Rong, Xiaomeng Zhao, Juntao Li, Yan Wang, Zhengzi Bi, Xiaozhu Bi, Haiwen Hu