Patents by Inventor Der-Chi TIEN

Der-Chi TIEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10117956
    Abstract: The present invention is related to a radiolabeled active targeting pharmaceutical composition, including: a bioconjugate and a radionuclide, wherein the bioconjugate includes a biomolecule and a metal nanoparticle, wherein the biomolecule has an affinity for receptors on the surface of a cell membrane and is selected from the group consisting of a peptide and a protein. The present invention further provides a method for evaluating a thermal adjuvant therapy for tumors and a kit thereof. The above-mentioned pharmaceutical composition is applied to evaluate a tumor accumulation time, so as to establish the optimal policy for a radiofrequency- or laser-induced thermal adjuvant therapy for tumors.
    Type: Grant
    Filed: September 14, 2017
    Date of Patent: November 6, 2018
    Assignee: INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN
    Inventors: Hsin-Ell Wang, Chien-Chung Hsia, Mao-Chi Weng, Kun-Liang Lin, Hao-Wen Kao, Chao-Cheng Chen, Kwan-Hwa Chi, Der-Chi Tien, Wuu-Jyh Lin
  • Publication number: 20180229052
    Abstract: A breast support device for radiation therapy includes a cuplike body with a through aperture. The cuplike body has a base portion and a compression portion connected continuously forming a concave inner surface, the compression portion is extended from the base portion, the concave inner surface have contours that fit over the female patient's breast as patient been in a predetermined posture. The through aperture is formed on the cuplike body to receive a portion of the female patient's breast through, it has a contour curve defined by a cutting plane and the contours of the patient's breast.
    Type: Application
    Filed: December 14, 2017
    Publication date: August 16, 2018
    Inventors: Long-Sheng LU, Kuo-Hsiung TSENG, Der-Chi TIEN, Meng-Yun CHUNG
  • Publication number: 20180117188
    Abstract: The present invention is related to a radiolabeled active targeting pharmaceutical composition, including: a bioconjugate and a radionuclide, wherein the bioconjugate includes a biomolecule and a metal nanoparticle, wherein the biomolecule has an affinity for receptors on the surface of a cell membrane and is selected from the group consisting of a peptide and a protein. The present invention further provides a method for evaluating a thermal adjuvant therapy for tumors and a kit thereof. The above-mentioned pharmaceutical composition is applied to evaluate a tumor accumulation time, so as to establish the optimal policy for a radiofrequency- or laser-induced thermal adjuvant therapy for tumors.
    Type: Application
    Filed: September 14, 2017
    Publication date: May 3, 2018
    Inventors: Hsin-Ell WANG, Chien-Chung HSIA, Mao-Chi WENG, Kun-Liang LIN, Hao-Wen KAO, Chao-Cheng CHEN, Kwan-Hwa CHI, Der-Chi TIEN, Wuu-Jyh LIN
  • Patent number: 9789214
    Abstract: The present invention is related to a radiolabeled active targeting pharmaceutical composition, including: a bioconjugate and a radionuclide, wherein the bioconjugate includes a biomolecule and a metal nanoparticle, wherein the biomolecule has an affinity for receptors on the surface of a cell membrane and is selected from the group consisting of a peptide and a protein. The present invention further provides a method for evaluating a thermal adjuvant therapy for tumors and a kit thereof. The above-mentioned pharmaceutical composition is applied to evaluate a tumor accumulation time, so as to establish the optimal policy for a radiofrequency- or laser-induced thermal adjuvant therapy for tumors.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: October 17, 2017
    Assignees: INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, EXECUTIVE YUAN, NATIONAL YANG-MING UNIVERSITY
    Inventors: Hsin-Ell Wang, Chien-Chung Hsia, Mao-Chi Weng, Kun-Liang Lin, Hao-Wen Kao, Chao-Cheng Chen, Kwan-Hwa Chi, Der-Chi Tien, Wuu-Jyh Lin
  • Publication number: 20150231285
    Abstract: The present invention is related to a radiolabeled active targeting pharmaceutical composition, including: a bioconjugate and a radionuclide, wherein the bioconjugate includes a biomolecule and a metal nanoparticle, wherein the biomolecule has an affinity for receptors on the surface of a cell membrane and is selected from the group consisting of a peptide and a protein. The present invention further provides a method for evaluating a thermal adjuvant therapy for tumors and a kit thereof. The above-mentioned pharmaceutical composition is applied to evaluate a tumor accumulation time, so as to establish the optimal policy for a radiofrequency- or laser-induced thermal adjuvant therapy for tumors.
    Type: Application
    Filed: September 18, 2014
    Publication date: August 20, 2015
    Inventors: Hsin-Ell WANG, Chien-Chung HSIA, Mao-Chi WENG, Kun-Liang LIN, Hao-Wen KAO, Chao-Cheng CHEN, Kwan-Hwa CHI, Der-Chi TIEN, Wuu-Jyh LIN
  • Publication number: 20100274151
    Abstract: An assisting method for radiotherapy is provided. The method detects the inspiratory and expiratory lung volumes of a patient lying on a supporting means to calculate displacement of the tumor adjacent to the diaphragm of the patient, and then drives the supporting means on which the patient lean to move in a direction opposite to the direction of the displacement of the tumor and in a distance equal to the distance of the displacement of the tumor, whereby the radioactive ray can be more accurately focused on the cancerous region of the patient. An assisting apparatus for radiotherapy is also proposed for enhancing the effect of radiotherapy treating on a tumor adjacent to the diaphragm.
    Type: Application
    Filed: April 6, 2010
    Publication date: October 28, 2010
    Inventors: Kwan-Hwa CHI, Der-Chi TIEN