Abstract: The present disclosure provides a method for anti-tampering apparatus servicing data implemented by a calculation device connected to a target device, the method comprising: identifying a contract identification code and obtaining a contract package file and a contract authentication code from at least one remote device; obtaining a microservice file corresponding to the target device from the remote device when a device embedded code of the calculation device is matching the contract authentication code; performing the microservice file to enable the target device according to the contract package file and generate an execution report; publishing the execution report to the remote device to obtain an acceptance certification code; and combining and hashing the device embedded code, the contract authentication code and the acceptance certification code to generate a hash value, and sending the hash value to a blockchain.

Abstract: The present disclosure is related to the six isomer structures (OBI-821-1990-V1A, OBI-821-1990-V1B, OBI-821-1990-V2A, OBI-821-1990-V2B, OBI-821-1858-A, and OBI-821-1858-B) of isolated OBI-821 adjuvant and the method for evaluating the quality thereof. The method of the present disclosure adopts hydrophilic interaction liquid chromatography (HILIC) and reverse phase high performance liquid chromatography (RP-HPLC) either alone or in tandem and is able to separate the isomers of OBI-821 adjuvant in the consequent chromatography. Accordingly, the quality of OBI-821 adjuvant can be further evaluated.

Abstract: A method for performing an in-memory computation includes: storing data in memory cells of a memory array, the data including weights for computation; determining whether an update command to change at least one of the weights is received; in response to receiving the update command, performing a write operation on the memory array to update the at least one weight; and disabling the write operation on the memory array until receiving a next update command to change the at least one weight.

Abstract: A memory device, such as an MRAM memory, includes a memory array with a plurality of bit cells. The memory array is configured to store trimming information and store user data. A sense amplifier is configured to read the trimming information from the memory array, and a trimming register is configured to receive the trimming information from the sense amplifier. The sense amplifier is configured to receive the trimming information from the trimming register so as to operate in a trimmed mode for reading the user data from the memory array.

Abstract: The present invention relates to antibodies or antigen-binding fragments thereof that specifically bind to the mesenchymal-epithelial transition factor (c-Met). The invention additionally relates to antibody drug conjugates (ADCs) comprising these anti-c-Met antibodies or antigen-binding fragments, pharmaceutical compositions comprising the antibodies, antigen-binding fragments or ADCs, and the use thereof in the treatment of cancer.

Abstract: Methods are presented for improving the efficiency of gas and/or fluid processing. The methods are applicable to fluid streams which may contain gas, liquid, entrainments, and combinations thereof. Embodiments are provided where inefficiencies in existing, for example, dehydration and/or condensation circuits are analyzed and further operations are added or removed or existing operations are relocated and/or removed. Other synergistic combinations are disclosed. The methods are predicated upon synergized amalgamation to realize the benefits of blended processing.

Abstract: A method reduces false-positive particle counts detected by an interference particle sensor module, which has a laser and a light detector. The method including: emitting laser light; providing a high-frequency signal during the emission of the laser light, a modulation frequency of the high-frequency signal being between 10-500 MHz; detecting an optical response by the light detector in reaction to the emitted laser light while providing the high-frequency signal, which is arranged such that a detection signal caused by a macroscopic object positioned between a first and second distance is reduced in comparison to a detection signal caused by the macroscopic object at the same position without providing the high-frequency signal. The high-frequency signal is provided to a tuning structure of the particle sensor module which is arranged to modify a resonance frequency of an optical resonator comprised by the laser sensor module upon reception of the high-frequency signal.

Abstract: The invention is directed to a process to manufacture an interconnected stack of thermoplastic frames having two sides by stacking the thermoplastic frames to obtain a stack of frames such that the facing sides of two neighbouring frames are in contact with each other at a contact area. When stacking a longitudinal conduit is formed which runs along the length of the stack and a branched conduit is formed at the contact area. The interconnected stack of thermoplastic frames are obtained by supplying a pressurised melt of a plastic material to the elongated conduit and branched conduits.

Abstract: The invention is directed to a process to manufacture an interconnected stack of thermoplastic frames having two sides by stacking the thermoplastic frames to obtain a stack of frames such that the facing sides of two neighbouring frames are in contact with each other at a contact area. When stacking a longitudinal conduit is formed which runs along the length of the stack and a branched conduit is formed at the contact area. The interconnected stack of thermoplastic frames are obtained by supplying a pressurised melt of a plastic material to the elongated conduit and branched conduits.

Abstract: The invention is directed to an evaporator plate heat exchanger comprising a water supply (1) and a water discharge (2) and a stack (4) of injected moulded frames (5) and heat exchange sheets (6), wherein the stack has two ends (7, 8) and at least four sides (9, 10, 11,12). The stack (4) has alternating first (13) and second (14) spaces between the heat exchange sheets (6). The stack (4) comprises a first enclosed space (15) at one side of the stack (4) which is fluidly connected to the first spaces (13) and not fluidly connected to the second spaces (14). The first enclosed space (15) is fluidly connected to the water supply (1).

Abstract: A system for configuring an ambulatory medical device includes an ambulatory medical device configured to monitor at least one electrocardiogram signal received from a patient for an occurrence of one or more cardiac events. The system also includes a remote computing device configured to receive a set of threshold values related to operation of the ambulatory medical device. The threshold values identify one or more conditions indicative of an occurrence of one or more cardiac events. The remote computing device is configured to query a master lookup table to determine a lookup code associated with the received set of threshold values, establish a communication link with the ambulatory medical device, receive an activation notification indicating that the ambulatory medical device has been activated, and encode a key. The encoded key includes the lookup code. The remote computing device is configured to transmit the encoded key to the ambulatory medical device.

Abstract: A power supply for a power line includes a synchronization module having a receiver configured for receiving a clock signal from a satellite-based positioning system and an oscillator configured for generating a periodic signal synchronized to the received clock signal. The power supply includes an inverter module having an inverter configured for supplying an AC voltage to the power line, receiving the periodic signal from the synchronization module, and controlling the inverter using the received periodic signal as a synchronization reference signal for the supplied AC voltage. The power supply further includes a power exchange control module configured for: monitoring an active power flow P from the inverter module to the power line, determining whether the active power flow P satisfies a reverse-flow condition, and when the reverse-flow condition is determined, adapting at least one of a phase and an output voltage of the supplied AC voltage.

Abstract: A laser sensor module includes a first laser source configured to emit first modulated light, the first modulated light being modulated laser light. The laser sensor module further includes circuitry configured to drive the first laser source with a first modulated driving current to cause the first laser source to emit the modulated laser light, a detector configured to detect the modulated laser light, which induces a photocurrent with variations resulting from modulation of the modulated laser light, and a second laser source configured to emit second modulated light. The circuitry is further configured to drive the second laser source with a second modulated driving current to cause the second laser source to emit the second modulated light. The detector is configured to detect the second modulated light. The circuitry is configured to adapt the amplitude of the second modulated driving current to induce a contribution to the photocurrent.

Abstract: A laser sensor module for detecting a particle density of small particles with a particle size between 0.05 ?m and 10 ?m includes a first laser configured to emit a first measurement beam, a second laser configured to emit a second measurement beam, and an optical arrangement configured to focus the first measurement beam to a first measurement volume and to focus the second measurement beam to a second measurement volume. The optical arrangement includes a first numerical aperture and a second numerical aperture arranged to detect a predetermined minimum particle size. The laser sensor module further includes a first detector configured to determine a first self-mixing interference signal of a first optical wave, a second detector configured to determine a second self-mixing interference signal of a second optical wave, and an evaluator.

Abstract: The invention relates to a method for detecting particles, having the steps of: receiving (S1) a measurement signal; calculating (S2) at least one estimated noise value using the received measurement signal; and detecting (S3) the particles using the measurement signal on the basis of at least one detection criterion, wherein the at least one detection criterion depends on the at least one calculated estimated noise value.

Abstract: The disclosed 2-D resistance tomographic imaging method optimizes computation speed for performing electrical impedance tomography using a model-space with a minimal number of orthonormal polynomial basis functions to describe discernable features in the 2-D resistance tomographic image, determining a minimal number of contacts to take fewer measurements than available information based on the number of basis functions, selecting a subset of rows of a matrix of calculated sensitivity coefficients to form a square Jacobian matrix for a linearized forward problem to be solved and inversion of the linear forward problem, and solving an inverse problem based on the square Jacobian matrix by performing at least one iteration of a Newton's method solve.

Abstract: The present invention relates to antibodies against the human 5T4 oncofoetal antigen and corresponding antibody-drug conjugates that are suitable for testing in clinical trials. The antibodies are cross-reactive for humans and cynomolgus monkeys and exhibit an affinity for human 5T4 antigen which is in the same order of magnitude as their affinity for cynomolgus monkey 5T4 antigen. The invention further relates to the use of the antibodies and corresponding ADCs in the treatment of solid tumours and haematological malignancies.

Abstract: The invention relates to a method for determining the absolute value of the flow velocity (v) of a particle-transporting medium. At least two measurement laser beams (L_i) with linearly independent, non-orthogonal measurement directions (b_i) are emitted. The measurement laser beams (L_i) scattered at particles are detected and one measurement signal (m_i) is generated in each case for each measurement laser beam (L_i).

Abstract: A semiconductor component for emitting light includes a main body that comprises at least one mesa body. The mesa body has an emission region for emitting the light. The emission region is assigned a first mirror portion, a second mirror portion, and an active portion arranged between the two mirror portions and serving to produce the light. The semiconductor component further includes electrical contacts for feeding electrical energy into the active portion, with at least one stress element that is attached to a surface of the main body. The stress element is configured to generate in the main body a material stress which has an effect on one or more polarization properties of the emitted light.

Abstract: The invention is directed to a modular gas flow system comprising at least a first and a second hollow cuboid shaped gas flow element. The four edges of at least one open face of the first gas flow element is connected in a gas tight manner to four edges of an open face of the second hollow cuboid shaped gas flow element. A valve or a partition is present at the connecting open faces. The gas flow system may be a header of a plate heat exchanger.