Abstract: Disclosed herein are stereocomplexes for the delivery of one or more anti-cancer agents. The stereocomplexes exhibit low toxicity and are biodegradable while also providing for controlled release of one or more anti-cancer agents at tumor sites. The stereocomplexes can be designed such that the anti-cancer agents operate synergistically and may optionally include additional targeting groups and functionalities. The stereocomplexes disclosed herein can be combined with pharmaceutically-acceptable carriers and/or excipients to form pharmaceutical compositions. By varying the amount of each anti-cancer agent in the stereocomplex, specific types of tumors and cancer cell lines can be treated.

Abstract: Disclosed herein are nanodroplet compositions composed of a copolymer with a hydrophilic block and a hydrophobic block, a poloxamer, an oil, an anti¬cancer agent, and optionally a lyoprotectant. The nanodroplet compositions exhibit low toxicity and are biodegradable, provide for slow, sustained release of the anti-cancer agent at tumor sites, and result in a greater reduction of tumor volume when administered to subjects with cancer as compared to several commercially-available products. Furthermore, the nanodroplet compositions can be imaged and their progress through the body tracked with magnetic resonance spectroscopy or ultrasound.

Abstract: Disclosed herein are nanodroplets containing (i) a tocotrienol, (ii) a tocopherol or tocotrienol covalently bonded to a polyalkylene glycol, (iii) a poloxamer, and (iv) a polyalkylene glycol. In certain aspects, the nanodroplets described herein have anti-cancer activity even in the absence of an anti-cancer agent (e.g., chemotherapeutic agents). Thus, the nanodroplets described herein can be used alone or in combination with one or more anti-cancer agents to treat cancer. The nanodroplets exhibit low toxicity, are biodegradable, and offer chemoprotective effects when administered alone or alongside traditional anti-cancer agents. Furthermore, the nanodroplets do not interfere with the efficacy of anti-cancer agents and result in a greater reduction of tumor volume when administered to subjects with cancer as compared to commercially-available products alone.

Abstract: Provided is a system, which includes: a radio frequency (RF) generator including an RF power, an RF signal generator configured to be initiated by the RF power and generates an RF signal; a heating apparatus including a first pouch having a first inlet tube, a second pouch having a second inlet tube connected to the first pouch, a first RF electrode in the first pouch and a second RF electrode in the second pouch, wherein the first RF electrode and the second RF electrode are configured to receive the RF signal; and a liquid reservoir operatively connected to the first inlet tube of the first pouch. Also provided is a method for treating a cancer in a subject in need thereof by using the system.

Abstract: A method and system for treating cancer of a patient are disclosed. In a first aspect, the method comprises injecting bleomycin into the patient and administering excorporeal ultrasound to a localized area of the cancer, wherein the bleomycin more readily enters the localized area to treat the cancer of the patient. In a second aspect, the system comprises an injection unit for injecting bleomycin into the patient and an ultrasound module for administering excorporeal ultrasound to a localized area of the cancer, wherein the bleomycin more readily enters the localized area to treat the cancer of the patient.

Abstract: A sound wave treatment platform is provided. The sound wave treatment platform includes a sound wave emitting module, a control module and a supporting component for receiving and supporting the sound wave emitting module. The sound wave emitting module includes a plurality of sound wave emitting devices for emitting non-focused sound waves. A sound wave treatment method is also provided. The sound wave treatment method includes the step of administering non-focused sound waves to a subject, wherein the non-focused sound waves are produced by a plurality of sound wave emitting devices.

Abstract: A method and system for leading macromolecule substances into target cells includes an image picking unit, an image merging unit, an injection unit, and an energy conversion module. The image picking unit is used for picking up the three-dimensional (3D) and the 3D blood vessel photographic images of the tissue or organ where the target cells locate. The image merging unit is used for merging the 3D structure images into the 3D blood vessel photographic images, therefore choosing a blood vessel passage fully covering the target cells for transmitting the macromolecule substances. The injection unit is used for injecting liquid and transmitting the macromolecule substances to the target cells. The energy conversion module is used for exerting energy to activate the liquid to perform biological effects, thereby forming non-permanent holes in the cell membranes of the target cells. The macromolecule substances enter into the target cells through the non-permanent holes.

Abstract: A method and system for leading macromolecule substances into target cells includes an image picking unit, an image merging unit, an injection unit, and an energy conversion module. The image picking unit is used for picking up the three-dimensional (3D) and the 3D blood vessel photographic images of the tissue or organ where the target cells locate. The image merging unit is used for merging the 3D structure images into the 3D blood vessel photographic images, therefore choosing a blood vessel passage fully covering the target cells for transmitting the macromolecule substances. The injection unit is used for injecting liquid and transmitting the macromolecule substances to the target cells. The energy conversion module is used for exerting energy to activate the liquid to perform biological effects, thereby forming non-permanent holes in the cell membranes of the target cells. The macromolecule substances enter into the target cells through the non-permanent holes.

Abstract: A method and system for leading macromolecule substances into target cells includes an image picking unit, an image merging unit, an injection unit, and an energy conversion module. The image picking unit is used for picking up the three-dimensional (3D) and the 3D blood vessel photographic images of the tissue or organ where the target cells locate. The image merging unit is used for merging the 3D structure images into the 3D blood vessel photographic images, therefore choosing a blood vessel passage fully covering the target cells for transmitting the macromolecule substances. The injection unit is used for injecting liquid and transmitting the macromolecule substances to the target cells. The energy conversion module is used for exerting energy to activate the liquid to perform biological effects, thereby forming non-permanent holes in the cell membranes of the target cells. The macromolecule substances enter into the target cells through the non-permanent holes.

Abstract: A hearing aid device includes a signal transforming unit for converting an analog sound signal received by a signal receiving unit to a digital signal; a memory unit for temporarily storing the digital signal; a sound processing module for reprocessing the sound signal stored in the memory unit via a microprocessing unit according to parameters set by a user; a sound control module for receiving the sound signal processed by the sound processing module and adjusting an output volume via the microprocessing unit; and a signal output unit for receiving and outputting the sound signal adjusted by the sound control module. By such arrangement, a speed, tone and/or volume of an output sound can be controlled using the hearing aid device to thereby help the user to receive and recognize the sound signal.

Abstract: A delivery device and a delivery method allow at least one substance to permeate through the skin. The delivery device includes at least a receiving member, a conductive member, and a controlling member. After the receiving member for storing the substance comes into contact with the skin, an electric field is generated within the receiving member, thereby micronizing molecules of the substance to allow the substance to permeate through the skin from the receiving member in a manner of electrophoresis or iontophoresis.

Abstract: An endoscope apparatus includes a head portion for capturing images, a flexible connecting member made of optical fibers, and a body. The connecting member is used to transmit image data and control signals. A lens is provided in the head portion and adjustable to obtain sharp and clear images. The images are converted into image files and transmitted to an external data processor for data analysis. The optical fibers are flexible, such that the connecting member can be rolled and received in the body when it is not in use. A carrying member is provided on the body to allow a user to conveniently carry the endoscope apparatus. A disposable cover is used to cover the head portion and part of the connecting member that are to be in contact with an internal body cavity of a human, and a clamping member is provided to fix the cover in place.

Abstract: An endoscopic device is proposed. The endoscopic device has a control guiding wire or guiding sleeve and a shape memory hollow catheter to adjust angle of rotation for a front end of the endoscopic device up to 180°, and the hollow catheter can be rotated by an angle up to 360°, such that cavities of the human body can be checked thoroughly. As the endoscopic device is fabricated at a low cost, it can be discarded after use without an infection concern that arises as a result of improper sterilization.

Abstract: A method and system for leading macromolecule substances into target cells includes an image picking unit, an image merging unit, an injection unit, and an energy conversion module. The image picking unit is used for picking up the three-dimensional (3D) and the 3D blood vessel photographic images of the tissue or organ where the target cells locate. The image merging unit is used for merging the 3D structure images into the 3D blood vessel photographic images, therefore choosing a blood vessel passage fully covering the target cells for transmitting the macromolecule substances. The injection unit is used for injecting liquid and transmitting the macromolecule substances to the target cells. The energy conversion module is used for exerting energy to activate the liquid to perform biological effects, thereby forming non-permanent holes in the cell membranes of the target cells. The macromolecule substances enter into the target cells through the non-permanent holes.

Abstract: A hearing aid device includes a signal transforming unit for converting an analog sound signal received by a signal receiving unit to a digital signal; a memory unit for temporarily storing the digital signal; a sound processing module for reprocessing the sound signal stored in the memory unit via a microprocessing unit according to parameters set by a user; a sound control module for receiving the sound signal processed by the sound processing module and adjusting an output volume via the microprocessing unit; and a signal output unit for receiving and outputting the sound signal adjusted by the sound control module. By such arrangement, a speed, tone and/or volume of an output sound can be controlled using the hearing aid device to thereby help the user to receive and recognize the sound signal.

Abstract: An endoscope apparatus includes a head portion for capturing images, a flexible connecting member made of optical fibers, and a body. The connecting member is used to transmit image data and control signals. A lens is provided in the head portion and adjustable to obtain sharp and clear images. The images are converted into image files and transmitted to an external data processor for data analysis. The optical fibers are flexible, such that the connecting member can be rolled and received in the body when it is not in use. A carrying member is provided on the body to allow a user to conveniently carry the endoscope apparatus. A disposable cover is used to cover the head portion and part of the connecting member that are to be in contact with an internal body cavity of a human, and a clamping member is provided to fix the cover in place.

Abstract: An inspection apparatus incorporates at least a stethoscope inspection mode and an ultrasonic wave inspection mode. A signal processing module converts the analog signals received by a conversion module into digital signals, and stores the digital signals in a storage unit. A communicate module transmits the digital signals to a data processing device comprising wireless communicating interface, and thus a user of the data processing device obtains the inspection results displayed on a display unit of the data processing device.