Patents by Inventor Der-Yuan CHEN

Der-Yuan CHEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKERS FOR PREDICTING IMMUNOGENICITY AND THERAPEUTIC RESPONSES TO ADALIMUMAB IN RHEUMATOID ARTHRITIS PATIENTS
    Publication number: 20240027444
    Abstract: A method for predicting an immunogenic and/or therapeutic response to adalimumab 5 from a sample extracted from a rheumatoid arthritis patient by testing the sample for the presence of biomarkers, the biomarkers being autoantibodies to antigens comprising SSB, TROVE2 and ZHX2.
    Type: Application
    Filed: November 11, 2021
    Publication date: January 25, 2024
    Applicants: Sengenics Corporation Pte Ltd, CHINA MEDICAL UNIVERSITY HOSPITAL
    Inventors: Jonathan Michael BLACKBURN, Arif ANWAR, Der-Yuan CHEN, Po-Ku CHEN
  • Method for diagnosis and subtyping of adult onset Still's disease
    Patent number: 11634776
    Abstract: The invention relates to method of diagnosis a subject suffering from Adult-onset Still's disease and further to determine the disease course of the subject suffering from Adult-onset Still's disease.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: April 25, 2023
    Assignee: CHINA MEDICAL UNIVERSITY
    Inventors: Der-Yuan Chen, Chin-An Yang
  • METHOD FOR DIAGNOSIS AND SUBTYPING OF ADULT ONSET STILL'S DISEASE
    Publication number: 20210388439
    Abstract: The invention relates to method of diagnosis a subject suffering from Adult-onset Still's disease and further to determine the disease course of the subject suffering from Adult-onset Still's disease.
    Type: Application
    Filed: June 10, 2020
    Publication date: December 16, 2021
    Applicant: CHINA MEDICAL UNIVERSITY
    Inventors: Der-Yuan Chen, Chin-An Yang
  • Method for detecting the risk and prognosis of adult-onset Still's disease
    Patent number: 11047012
    Abstract: The present invention discloses a new biomarker miR-134, miR-223, or IL-18, which is positively correlated with AOSD and activities thereof. By detecting the expression level of at least one biomarker in a sample, an effect of detecting the risk and prognosis of a sample provider suffering from a disease is achieved.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: June 29, 2021
    Assignee: TAICHUNG VETERANS GENERAL HOSPITAL
    Inventors: Tsai-Ling Liao, Der-Yuan Chen
  • METHOD FOR EVALUATING THE STATUS OF LATENT TUBERCULOSIS INFECTION, METHOD FOR EVALUATING THE EFFECT OF THE METHOD FOR TREATING THE SAME, AND TREATMENT METHOD THEREOF
    Publication number: 20190352701
    Abstract: The present invention discloses a method for evaluating the status of latent tuberculosis infection, a method for evaluating the effect of a treatment therefor, and a treatment therefor. In the method for evaluating the status of latent tuberculosis infection, and the method for evaluating the effect of a treatment therefor, the expression level (s) of miR-889 and/or TWEAK are/is detected and used as a basis for analysis.
    Type: Application
    Filed: September 27, 2018
    Publication date: November 21, 2019
    Inventors: Tsai-Ling Liao, Der-Yuan Chen
  • METHOD FOR DETECTING THE RISK AND PROGNOSIS OF ADULT-ONSET STILL'S DISEASE
    Publication number: 20190345555
    Abstract: The present invention discloses a new biomarker miR-134, miR-223, or IL-18, which is positively correlated with AOSD and activities thereof. By detecting the expression level of at least one biomarker in a sample, an effect of detecting the risk and prognosis of a sample provider suffering from a disease is achieved.
    Type: Application
    Filed: June 21, 2018
    Publication date: November 14, 2019
    Inventors: Tsai-Ling LIAO, Der-Yuan CHEN
  • Method for modulating Th17 cells and method for treating a disease related to modulation of Th17 cells
    Patent number: 9603882
    Abstract: The disclosure provides a method for modulating Th17 cells, including: administering an Antrodia cinnamomea (also named Antrodia camphorata or Taiwanofungus camphoratus) extract to a subject in need thereof, wherein the Antrodia cinnamomea extract has an effect of modulating Th17 cells. The Antrodia cinnamomea extract may include a fruiting body extract of Antrodia cinnamomea or a mycelium extract of Antrodia cinnamomea.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: March 28, 2017
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: I-Horng Pan, Shu-Fang Wen, Ming-Han Li, Hsin-Jan Yao, Hsin-Chieh Wu, I-Huang Lu, Joung-Liang Lan, Der-Yuan Chen, Chi-Chien Lin, Ching Lu
  • METHOD FOR MODULATING TH17 CELLS AND METHOD FOR TREATING A DISEASE RELATED TO MODULATION OF TH17 CELLS
    Publication number: 20150050315
    Abstract: The disclosure provides a method for modulating Th17 cells, including: administering an Antrodia cinnamomea (also named Antrodia camphorata or Taiwanofungus camphoratus) extract to a subject in need thereof, wherein the Antrodia cinnamomea extract has an effect of modulating Th17 cells. The Antrodia cinnamomea extract may include a fruiting body extract of Antrodia cinnamomea or a mycelium extract of Antrodia cinnamomea.
    Type: Application
    Filed: July 3, 2014
    Publication date: February 19, 2015
    Inventors: I-Horng PAN, Shu-Fang WEN, Ming-Han LI, Hsin-Jan YAO, Hsin-Chieh WU, I-Huang LU, Joung-Liang LAN, Der-Yuan CHEN, Chi-Chien LIN, Ching LU