Patents by Inventor Derek A. Cogan

Derek A. Cogan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240376113
    Abstract: The present disclosure relates generally to inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to triazolopyrimidine and imidazolopyrimidine inhibitors of ENPP1 and methods of their use for treating disease mediated by ENPP1.
    Type: Application
    Filed: July 12, 2024
    Publication date: November 14, 2024
    Applicant: Volastra Therapeutics, Inc.
    Inventors: Sarah BETTIGOLE, Michael SU, Derek A. COGAN, Leon VAN BERKOM, Piotr NIECZYPOR, Gydo VAN DER HEIJDEN, Prashanna VIJAYACHANDRAN
  • Publication number: 20240351984
    Abstract: The present disclosure relates generally to inhibitors of KIF18A, compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to indoline inhibitors of KIF18A and methods of their use for treating disease mediated by KIF18A, such as cancer.
    Type: Application
    Filed: June 5, 2024
    Publication date: October 24, 2024
    Applicant: Volastra Therapeutics, Inc.
    Inventor: Derek A. COGAN
  • Patent number: 12091412
    Abstract: The present disclosure relates generally to inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to triazolopyrimidine and imidazolopyrimidine inhibitors of ENPP1 and methods of their use for treating disease mediated by ENPP1.
    Type: Grant
    Filed: June 15, 2021
    Date of Patent: September 17, 2024
    Assignee: Volastra Therapeutics, Inc.
    Inventors: Sarah Bettigole, Michael Su, Derek A. Cogan, Leon Van Berkom, Piotr Nieczypor, Gydo Van Der Heijden, Prashanna Vijayachandran
  • Patent number: 12084420
    Abstract: The present disclosure relates generally to inhibitors of KIF18A, compositions thereof, and methods of using the compounds and compositions thereof. More specifically, the present disclosure relates to indoline inhibitors of KIF18A and methods of their use for treating disease mediated by KIF18A, such as cancer.
    Type: Grant
    Filed: August 25, 2022
    Date of Patent: September 10, 2024
    Assignee: Volastra Therapeutics, Inc.
    Inventor: Derek A. Cogan
  • Publication number: 20230382889
    Abstract: The present disclosure relates generally to inhibitors of KIF18A, compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to inhibitors of KIF18A and methods of their use for treating disease mediated by KIF18A, such as cancer.
    Type: Application
    Filed: April 27, 2023
    Publication date: November 30, 2023
    Applicant: Volastra Therapeutics, Inc.
    Inventor: Derek A. COGAN
  • Patent number: 11780849
    Abstract: The present disclosure relates generally to inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to sulfoximine-based inhibitors of ENPP1 and methods of their use for treating disease mediated by ENPP1.
    Type: Grant
    Filed: May 3, 2021
    Date of Patent: October 10, 2023
    Assignee: Volastra Therapeutics, Inc.
    Inventors: Derek A. Cogan, Sarah Bettigole, Leon Van Berkom, Piotr Nieczypor, Michael Su, Rutger Folmer
  • Publication number: 20230147507
    Abstract: The present disclosure relates generally to inhibitors of KIF18A, compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to indoline inhibitors of KIF18A and methods of their use for treating disease mediated by KIF18A, such as cancer.
    Type: Application
    Filed: August 25, 2022
    Publication date: May 11, 2023
    Applicant: Volastra Therapeutics, Inc.
    Inventor: Derek A. COGAN
  • Publication number: 20230036933
    Abstract: The present disclosure relates generally to inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to triazolopyrimidine and imidazolopyrimidine inhibitors of ENPP1 and methods of their use for treating disease mediated by ENPP1.
    Type: Application
    Filed: June 15, 2021
    Publication date: February 2, 2023
    Applicant: Volastra Therapeutics, Inc.
    Inventors: Sarah BETTIGOLE, Michael SU, Derek A. COGAN, Leon VAN BERKOM, Piotr NIECZYPOR, Gydo VAN DER HEIJDEN, Prashanna VIJAYACHANDRAN
  • Publication number: 20230002406
    Abstract: The present disclosure relates generally to inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to sulfoximine-based inhibitors of ENPP1 and methods of their use for treating disease mediated by ENPP1.
    Type: Application
    Filed: May 3, 2021
    Publication date: January 5, 2023
    Applicant: Volastra Therapeutics, Inc.
    Inventors: Derek A. COGAN, Sarah BETTIGOLE, Leon VAN BERKOM, Piotr NIECZYPOR, Michael SU, Rutger FOLMER
  • Patent number: 7569568
    Abstract: Disclosed are compounds of formula (I) Where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: September 7, 2006
    Date of Patent: August 4, 2009
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Derek A. Cogan, Ming-Hong Hao, Kevin Chungeng Qian, Alan David Swinamer
  • Patent number: 7166628
    Abstract: Disclosed are compounds of formula (I) Where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.
    Type: Grant
    Filed: November 20, 2003
    Date of Patent: January 23, 2007
    Assignee: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Derek A. Cogan, Ming-Hong Hao, Kevin Chungeng Qian, Alan David Swinamer
  • Publication number: 20040102492
    Abstract: Disclosed are compounds of formula (I) 1
    Type: Application
    Filed: November 20, 2003
    Publication date: May 27, 2004
    Applicant: Boehringer Ingelheim Pharmaceuticals, Inc.
    Inventors: Derek A. Cogan, Ming-Hong Hao, Kevin Chungeng Qian, Alan David Swinamer