Abstract: An expandable augment system is provided for use with an acetabular cup. The expandable augment system can include an expandable augment module that is adjustable in size and that can be adjusted incrementally between a fully collapsed state and an expanded state. A first portion of the expandable augment module is attachable to an outer surface of an acetabular cup and a second portion of the expandable augment module is attachable to bone or to a fixed augment module (e.g., a fixed angle augment module) that is attached to bone and interposed between the adjustable augment module and bone.

Abstract: A method includes, at a first time: accessing a first image of a surgical field during a surgical operation; and identifying a first quantity of unused units of a first consumable type in the first image. The method also includes, at a second time: accessing a second image of the surgical field; and identifying a second quantity of unused units of the first consumable type in the second image. The method also includes: predicting a total consumption quantity of the first consumable type during the surgical operation based on a difference between the first quantity and the second quantity; and, in response to the second quantity falling below the total consumption quantity, rendering a prompt on a display, adjacent to an exit of the operating room, to retrieve a set of units of the first consumable type.

Abstract: A system including a knee ranging tool: including a base configured to locate on a resected proximal face of a tibia in a knee of a patient; defining a tibial reference surface configured to run against a femoral surface of an artificial femoral component, installed on a distal face of a femur of the patient, during articulation of the knee of patient; including a set of stages interposed between the base and the tibial reference surface, configured to locate the tibial reference surface relative to the base, and compliant to medial-lateral translation, anteroposterior translation, and transverse rotation; and configured to indicate a medial-lateral translation offset, an anteroposterior translation offset, and a transverse rotation offset corresponding to a position of the tibial reference surface, relative to the base, that yields elastic deformation of ligaments in the knee over a range of motion of the knee.

Abstract: A modular system for total knee arthroplasty includes a modular trial implant assembly. The modular implant assembly includes an elongate shaft configured for insertion into an elongate cavity in a bone, a reamer removably coupleable to the elongate shaft via a connection that allows the reamer to rotate while the elongate shaft remains in a substantially fixed angular orientation. The reamer has an outer surface that tapers toward the distal end configured to form a tapered cavity in an end of a bone in which the reamer is inserted and rotated. The modular trial implant assembly further includes a trial implant removably coupleable to a proximal end of the reamer. A modular final implant assembly includes an elongate stem, a tapered body and an implant body, each having a size and shape that can substantially correspond to a size and shape of the elongate shaft, the reamer and the trial implant, respectively.

Abstract: Once variation of a system for total knee replacement includes: a first alignment guide defining first set of guides that locate a first set of pins on a first bone of a joint in extension and defining a reference surface relative to the first set pin guides; a second alignment guide constrained relative to the first alignment guide by the reference surface and defining a second set of guides, relative to the first set of guides, that locate a second set of pins on a second bone of the joint; a first cut guide located by the first set of pins and defining a first cut plane for resecting the first bone; and a second cut guide located by the second set of pins and defining a second cut plane, linearly offset from the first cut plane, for resecting the second bone.

Abstract: A method for generating intraoperative surgical guidance during a knee arthroplasty includes: preceding resection of a first bone and a second bone in a knee of a patient, generating a first ligament tension curve for a first ligament in the knee; generating a second ligament tension curve for a second ligament in the knee; storing a first target tension curve for the first ligament based on the first ligament tension curve; and, succeeding resection of the first bone and succeeding placement of a first test implant on the first bone, generating a third ligament tension curve for the first ligament; characterizing a first phase difference between the third ligament tension curve and the first target tension curve; and in response to the first phase difference exceeding a threshold negative phase difference, outputting a first prompt to a surgeon to further resect the first bone proportional to the first phase difference.

Abstract: An expandable augment system is provided for use with an acetabular cup. The expandable augment system can include an expandable augment module that is adjustable in size and that can be adjusted incrementally between a fully collapsed state and an expanded state. A first portion of the expandable augment module is attachable to an outer surface of an acetabular cup and a second portion of the expandable augment module is attachable to bone or to a fixed augment module (e.g., a fixed angle augment module) that is attached to bone and interposed between the adjustable augment module and bone.

Abstract: Provided herein are hydrogels that include a plurality of bacteriophages located within and covalently bonded to the hydrogel interior. The hydrogel is engineered to facilitate a controlled sustained release of the connected bacteriophages, e.g., to or within the body of a patient suffering from a bacterial infection. Also provided are methods for forming the provided hydrogels, and for using the hydrogels to treat a patient suffering from a bacterial infection.

Abstract: An expandable augment system is provided for use with an acetabular cup. The expandable augment system can include an expandable augment module that is adjustable in size and that can be adjusted incrementally between a fully collapsed state and an expanded state. A first portion of the expandable augment module is attachable to an outer surface of an acetabular cup and a second portion of the expandable augment module is attachable to bone or to a fixed augment module (e.g., a fixed angle augment module) that is attached to bone and interposed between the adjustable augment module and bone.

Abstract: Off-center liners can be used with an acetabular cup in hip replacement or revision surgical procedures. The liners (of metal or plastic) can be laterally spaced from the acetabular cup, angled relative to the acetabular cup and/or have an opening that is offset relative to the axis of the acetabular cup. The liners have an orientation indicator that identifies where the liner should be impacted (e.g., impaction location or point) by the impactor to ensure the liner is impacted in a square manner relative to the acetabular cup.

Abstract: Once variation of a system for total knee replacement includes: a first alignment guide defining first set of guides that locate a first set of pins on a first bone of a joint in extension and defining a reference surface relative to the first set pin guides; a second alignment guide constrained relative to the first alignment guide by the reference surface and defining a second set of guides, relative to the first set of guides, that locate a second set of pins on a second bone of the joint; a first cut guide located by the first set of pins and defining a first cut plane for resecting the first bone; and a second cut guide located by the second set of pins and defining a second cut plane, linearly offset from the first cut plane, for resecting the second bone.

Abstract: Off-center liners can be used with an acetabular cup in hip replacement or revision surgical procedures. The liners (of metal or plastic) can be laterally spaced from the acetabular cup, angled relative to the acetabular cup and/or have an opening that is offset relative to the axis of the acetabular cup. The liners have an orientation indicator that identifies where the liner should be impacted (e.g., impaction location or point) by the impactor to ensure the liner is impacted in a square manner relative to the acetabular cup.

Abstract: Once variation of a system includes: a femoral head including a shank configured to seat on a neck of a femoral stem component installed on a femur, a spherical shell arranged over the shank, force sensors configured to output force data representing forces acting on the spherical shell, and inertial sensors configured to output orientation data representing orientations of the femoral head; a reference module configured to couple to a pelvis of a patient and output reference orientation data representing orientations of the pelvis; and a controller configured to access the force data, the orientation data, and the reference orientation data, calculate orientations of the femoral head relative the pelvis, and based on the orientations of the femoral head and the force data, calculate a force versus angular orientation curve representing forces exerted on the femoral head by the pelvis over a range of motion of the femur.

Abstract: A method includes accessing a three-dimensional representation of a surgical space and based on the three-dimensional representation, for each object in a first constellation of objects: extracting a first location of the object; detecting a first object type of the object; deriving a first surgical status of the object; calculating a first ranking score of the object based on the first object type and the first surgical status; and storing the first location, the first object type, the first surgical status, and the first ranking score in an object container in a set of object containers. The method also includes selecting a first target object at a first time based on a first target ranking score; articulating a mobile camera to locate a first target location of the first target object; and deriving a trajectory of the first target object based on the set of object containers.

Abstract: An expandable augment system is provided for use with an acetabular cup. The expandable augment system can include an expandable augment module that is adjustable in size and that can be adjusted incrementally between a fully collapsed state and an expanded state. A first portion of the expandable augment module is attachable to an outer surface of an acetabular cup and a second portion of the expandable augment module is attachable to bone or to a fixed augment module (e.g., a fixed angle augment module) that is attached to bone and interposed between the adjustable augment module and bone.

Abstract: Off-center liners can be used with an acetabular cup in hip replacement or revision surgical procedures. The liners (of metal or plastic) can be laterally spaced from the acetabular cup, angled relative to the acetabular cup and/or have an opening that is offset relative to the axis of the acetabular cup. The liners have an orientation indicator that identifies where the liner should be impacted (e.g., impaction location or point) by the impactor to ensure the liner is impacted in a square manner relative to the acetabular cup.

Abstract: A method for generating intraoperative surgical guidance during a knee arthroplasty includes: preceding resection of a first bone and a second bone in a knee of a patient, generating a first ligament tension curve for a first ligament in the knee; generating a second ligament tension curve for a second ligament in the knee; storing a first target tension curve for the first ligament based on the first ligament tension curve; and, succeeding resection of the first bone and succeeding placement of a first test implant on the first bone, generating a third ligament tension curve for the first ligament; characterizing a first phase difference between the third ligament tension curve and the first target tension curve; and in response to the first phase difference exceeding a threshold negative phase difference, outputting a first prompt to a surgeon to further resect the first bone proportional to the first phase difference.

Abstract: A method for generating intraoperative surgical guidance during a knee arthroplasty includes: preceding resection of a first bone and a second bone in a knee of a patient, generating a first ligament tension curve for a first ligament in the knee; generating a second ligament tension curve for a second ligament in the knee; storing a first target tension curve for the first ligament based on the first ligament tension curve; and, succeeding resection of the first bone and succeeding placement of a first test implant on the first bone, generating a third ligament tension curve for the first ligament; characterizing a first phase difference between the third ligament tension curve and the first target tension curve; and in response to the first phase difference exceeding a threshold negative phase difference, outputting a first prompt to a surgeon to further resect the first bone proportional to the first phase difference.

Abstract: A modular system for total knee arthroplasty includes a modular trial implant assembly. The modular implant assembly includes an elongate shaft configured for insertion into an elongate cavity in a bone, a reamer removably coupleable to the elongate shaft via a connection that allows the reamer to rotate while the elongate shaft remains in a substantially fixed angular orientation. The reamer has an outer surface that tapers toward the distal end configured to form a tapered cavity in an end of a bone in which the reamer is inserted and rotated. The modular trial implant assembly further includes a trial implant removably coupleable to a proximal end of the reamer. A modular final implant assembly includes an elongate stem, a tapered body and an implant body, each having a size and shape that can substantially correspond to a size and shape of the elongate shaft, the reamer and the trial implant, respectively.

Abstract: One variation of a method includes: accessing a virtual patient model defining a target resected contour of a hard tissue of interest; after resection of the hard tissue of interest during a surgical operation, accessing an optical scan recorded by an optical sensor facing a surgical field occupied by a patient, detecting a set of features representing the patient in the optical scan, registering the virtual patient model to the hard tissue of interest in the surgical field based on the set of features, and detecting an actual resected contour of the hard tissue of interest in the optical scan; and calculating a spatial difference between the actual resected contour of the hard tissue of interest and the target resected contour of the hard tissue of interest represented in the virtual patient model registered to the hard tissue of interest in the surgical field.