Abstract: Disclosed are nucleic acid oligomer compounds and to their use in compositions and methods for inhibiting proliferation, survival or viability of cancer cells including prostate, lung, pancreatic, breast, cervical and bone cancer cells.

Abstract: Some embodiments of the invention provide a novel network architecture for deploying guest clusters (GCs) including workload machines for a tenant (or other entity) within an availability zone. The novel network architecture includes a virtual private cloud (VPC) deployed in the availability zone (AZ) that includes a centralized routing element that provides access to a gateway routing element of the AZ. In some embodiments, the centralized routing element provides a set of services for packets traversing a boundary of the VPC. The services, in some embodiments, include load balancing, firewall, quality of service (QoS) and may be stateful or stateless. Guest clusters are deployed within the VPC and use the centralized routing element of the VPC to access the gateway routing element of the AZ.

Abstract: The disclosure provides an approach for the dynamic configuration of virtualized objects. A virtual object may be associated with a desired state defining a first plurality of resources for allocating to the virtual object. The first plurality of resources correspond to one or more resource types. Techniques include determining that each of a plurality of hosts does not have sufficient available resources to allocate the first plurality of resources to the virtual object according to the desired state. Techniques include selecting, a first host of the plurality of hosts to run the virtual object. Techniques include allocating a second plurality of resources to the virtual object from the first host, wherein the second plurality of resources is less than the first plurality of resources, and running the virtual object in the first host.

Abstract: A computer system implements a file system migration by determining a destination namespace of a destination file system based at least in part on a namespace of a source file system. At least a portion of the destination namespace includes an organization that is altered as compared to a corresponding portion of the source namespace.

Abstract: The disclosure provides an approach for the dynamic configuration of virtualized objects. A virtual object may be associated with a desired state defining a first plurality of resources for allocating to the virtual object. The first plurality of resources correspond to one or more resource types. Techniques include determining that each of a plurality of hosts does not have sufficient available resources to allocate the first plurality of resources to the virtual object according to the desired state. Techniques include selecting, a first host of the plurality of hosts to run the virtual object. Techniques include allocating a second plurality of resources to the virtual object from the first host, wherein the second plurality of resources is less than the first plurality of resources, and running the virtual object in the first host.

Abstract: Some embodiments of the invention provide a novel network architecture for deploying guest clusters (GCs) including workload machines for a tenant (or other entity) within an availability zone. The novel network architecture includes a virtual private cloud (VPC) deployed in the availability zone (AZ) that includes a centralized routing element that provides access to a gateway routing element of the AZ. In some embodiments, the centralized routing element provides a set of services for packets traversing a boundary of the VPC. The services, in some embodiments, include load balancing, firewall, quality of service (QoS) and may be stateful or stateless. Guest clusters are deployed within the VPC and use the centralized routing element of the VPC to access the gateway routing element of the AZ.

Abstract: A computer system implements a file system migration by determining a destination namespace of a destination file system based at least in part on a namespace of a source file system. At least a portion of the destination namespace includes an organization that is altered as compared to a corresponding portion of the source namespace.

Abstract: A computer system implements a file system migration by determining a destination namespace of a destination file system based at least in part on a namespace of a source file system. At least a portion of the destination namespace includes an organization that is altered as compared to a corresponding portion of the source namespace.

Abstract: Instructions to fork a source VM are received, and execution of the source VM is temporarily stunned. A destination VM is created, and a snapshot of a first virtual disk of the source VM is created. A checkpoint state of the source VM is transferred to the destination VM. The source VM has one or more virtual disks. One or more virtual disks associated with the destination VM are created and reference the one or more virtual disks of the source VM. Execution of the destination VM is restored using the transferred checkpoint state and the virtual disks of the destination VM in a way that allows the source VM to also resume execution. Forking VMs using the described operation provisions destination VMs in a manner that makes efficient use of memory and disk space, while enabling source VMs to continue execution after completion of the fork operation.

Abstract: Instructions to fork a source VM are received, and execution of the source VM is temporarily stunned. A destination VM is created, and a snapshot of a first virtual disk of the source VM is created. A checkpoint state of the source VM is transferred to the destination VM. The source VM has one or more virtual disks. One or more virtual disks associated with the destination VM are created and reference the one or more virtual disks of the source VM. Execution of the destination VM is restored using the transferred checkpoint state and the virtual disks of the destination VM in a way that allows the source VM to also resume execution. Forking VMs using the described operation provisions destination VMs in a manner that makes efficient use of memory and disk space, while enabling source VMs to continue execution after completion of the fork operation.

Abstract: Examples described herein include a computer system, positioned in-line with respect to a plurality of clients that actively use a source file system, to replicate a source file system on a target memory in presence of out-of-band events which after the source file system.

Abstract: Examples described herein include a computer system, positioned in-line with respect to a plurality of clients that actively use a source file system, to replicate a source file system on a target memory in presence of out-of-band events which after the source file system.

Abstract: A data migration system in which security policies of a source file system are preserved, in an environment in which clients actively issue communications for the source filer while data is migrated to a destination file system.

Abstract: A computer system implements a file system migration by determining a destination namespace of a destination file system based at least in part on a namespace of a source file system. At least a portion of the destination namespace includes an organization that is altered as compared to a corresponding portion of the source namespace.

Abstract: A network attached storage (NAS) caching appliance, system, and associated method of operation for caching a networked file system. Still further, some embodiments provide for a cache system that implements a mufti-tiered, policy-influenced block replacement algorithm.

Abstract: Examples described herein include a computer system, positioned in-line with respect to a plurality of clients that actively use a source file system, to replicate a source file system on a target memory in presence of out-of-band events which alter the source file system.

Abstract: A system for migrating data from a source file system to a destination file system while the source file system is in active use, in part by transitioning the client's use of the source file system to that of the destination file system without unmounting the client from the source file system.

Abstract: A system for migrating data from a source file system to a destination file system, in a manner that is transparent and seamless to clients of the source file system.

Abstract: A data migration system in which security policies of a source file system are preserved, in an environment in which clients actively issue communications for the source filer while data is migrated to a destination file system.

Abstract: A system for migrating data from a source file system to a destination file system, in a manner that is transparent and seamless to clients of the source file system.