Abstract: The invention is directed to methods and systems of hyperspectral and multispectral imaging of medical tissues. In particular, the invention is directed to new devices, tools and processes for the detection and evaluation of diseases and disorders such as, but not limited to diabetes and peripheral vascular disease and cancer, that incorporate hyperspectral or multispectral imaging.

Abstract: The invention is directed to methods and systems of hyperspectral and multispectral imaging of medical tissues. In particular, the invention is directed to new devices, tools and processes for the detection and evaluation of diseases and disorders such as, but not limited to diabetes and peripheral vascular disease, that incorporate hyperspectral or multispectral imaging.

Abstract: This invention relates generally to an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment. The index map may also be a map of perfusion and/or metabolism of the tissue (reflecting oxygen delivery and oxygen extraction, obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging. This information aids treatment in prevention of diabetic foot ulceration and amputation and in treatment of tissue compromise to prevent tissue loss in other body regions.

Abstract: The invention is directed to methods and systems of hyperspectral and multispectral imaging of medical tissues. In particular, the invention is directed to new devices, tools and processes for the detection and evaluation of diseases and disorders such as, but not limited to diabetes and peripheral vascular disease, that incorporate hyperspectral or multispectral imaging.

Abstract: Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.

Abstract: Hyperspectral imaging calibration devices and methods for their use are described that generate images of three dimensional samples. A calibration device may assume the shape of a desired imaging sample such as a body part and may be sterile prior to placement. The calibration device may include openings or may be modified to expose a region of the sample during use. Spectral images, typically obtained at multiple wavelengths, are made of the calibration device. Algorithms are provided that utilize the spectral images of the calibration device to determine the effects of lighting conditions and sample shape on the sample image to form a calibrated image. Calibrated images produced by these devices and methods can provide information, including clinical data that are less sensitive to lighting and sample shape compared to alternative technologies.

Abstract: Hyperspectral imaging calibration devices and methods for their use are described that generate images of three dimensional samples. A calibration device may assume the shape of a desired imaging sample such as a body part and may be sterile prior to placement. The calibration device may include openings or may be modified to expose a region of the sample during use. Spectral images, typically obtained at multiple wavelengths, are made of the calibration device. Algorithms are provided that utilize the spectral images of the calibration device to determine the effects of lighting conditions and sample shape on the sample image to form a calibrated image. Calibrated images produced by these devices and methods can provide information, including clinical data that are less sensitive to lighting and sample shape compared to alternative technologies.

Abstract: Hyperspectral imaging calibration devices and methods for their use are described that generate images of three dimensional samples. A calibration device may assume the shape of a desired imaging sample such as a body part and may be sterile prior to placement. The calibration device may include openings or may be modified to expose a region of the sample during use. Spectral images, typically obtained at multiple wavelengths, are made of the calibration device. Algorithms are provided that utilize the spectral images of the calibration device to determine the effects of lighting conditions and sample shape on the sample image to form a calibrated image. Calibrated images produced by these devices and methods can provide information, including clinical data that are less sensitive to lighting and sample shape compared to alternative technologies.

Abstract: Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.

Abstract: Hyperspectral imaging calibration devices and methods for their use are described that generate images of three dimensional samples. A calibration device may assume the shape of a desired imaging sample such as a body part and may be sterile prior to placement. The calibration device may include openings or may be modified to expose a region of the sample during use. Spectral images, typically obtained at multiple wavelengths, are made of the calibration device. Algorithms are provided that utilize the spectral images of the calibration device to determine the effects of lighting conditions and sample shape on the sample image to form a calibrated image. Calibrated images produced by these devices and methods can provide information, including clinical data that are less sensitive to lighting and sample shape compared to alternative technologies.

Abstract: Instruments and methods are described for performing non-invasive measurements of analyte levels and for monitoring, analyzing and regulating tissue status, such as tissue glucose levels.

Abstract: This invention relates to the reduction of inter-subject variation via transfer standardization. According to the method, the effects of inter-subject variation on the analysis of spectra collected from the skin of two or more different subjects is reduced by correcting for the differences between spectra collected from said two or more subjects.

Abstract: A hammering game apparatus has a pair of mechanically articulated hammer devices coupled with a base mounting a motor-driven revolving platform. The platform has a plurality of pegs protruding through it. One or more players attempt to hammer down the pegs into the base with the hammer device(s). The pegs are driven from a raised position to a lower position on the platform with two longer pegs engaging a stop beneath the platform when driven sufficiently down into the platform. The platform is spring-supported and is pressed down towards the base to raise the pegs back to the raised position.

Abstract: Toy vehicles having a rigid body supported by wheel assemblies for movement on a support surface. A spring element is positioned between the vehicle body and the wheel assemblies for biasing the vehicle body in a normally raised position with respect to the wheel assemblies. A movable member is mounted on the body and is in contact with the wheel assembly and/or the spring element. The movable member is activated by the wheel assembly and/or the spring element as the vehicle body is lowered by a user and raised by the spring bias.

Abstract: A target shooting apparatus including an operator controlled simulated gun which projects a light beam of short duration toward a target each time the trigger is actuated. The simulated gun must be cocked between each "shot" which also resets a recoiling mechanism to give a true to life operational effect to the gun. The target includes a frame fronted by a simulated fence on top of which a plurality of objects, such as bottles, tin cans, and the like may be placed. A target impeller is provided on the frame in proximity to each of the objects so that, when actuated, the impeller will cause physical movement of the associated target knocking it off of the frame. The target impellers are actuated by a control mechanism, as a photo transistor therein senses the proper alignment of the light beam from the gun through one of a plurality of apertures located on the frame below each of the objects.

Abstract: A toy racing game accessory comprising a tachometer and fuel gauge. The tachometer includes a rack and pinion assembly which is driven by a linear actuator. A tachometer needle is coupled to the rack and pinion assembly. The action of the linear actuator is proportioned to the amplitude of current passing through the track rails and toy car motor as determined by a speed throttle. The fuel gauge includes a ratchet wheel. The rack and pinion assembly includes a pawl which advances the ratchet wheel if the tachometer needle is made to advance beyond a predetermined threshold speed. The ratchet pawl advances the ratchet wheel so as to cause the fuel gauge needle to advance towards "empty". The amount of advance of the fuel gauge needle depends on the swing of the tachometer. When the fuel gauge reads "empty" a cammed microswitch opens to cut off all power to the track rails and bring the racing car to a halt.

Abstract: A toy vehicle movable on a track operates an accessory with its wheels when it abuts a stop member. A manually operable remote control is used to then reverse the rotation of the wheels to remove the vehicle from the stop member.

Abstract: The apparatus provides for the automatic uncoupling of a toy semitrailer from a toy tractor truck and provides also for automatic coupling of a toy semitrailer to a toy tractor truck. The uncoupling utilizes a ramp in a roadway which is inboard of the tractor truck wheels, and this ramp is engaged by the forward dolly wheels on the semitrailer, which dolly wheels are also inboard of the truck tractor wheels. The coupling of the toy semitrailer to the toy tractor is achieved by a simple beveled end on the rear of the toy tractor, which backs up to the semitrailer, and the king pin of the semitractor rides up this bevel to the pivot flat area of the tractor to drop into the pivot hole. Both operations are carried out in the same locality by a reciprocating dock which is contacted by the semitrailer during its backing up at the time its dolly wheels ride up the ramp to release the tractor.

Abstract: A target shooting apparatus including an operator controlled simulated gun which projects a light beam of short duration toward a target each time the trigger is actuated. The simulated gun must be cocked between each "shot" which also resets a recoiling mechanism to give a true to life operational effect to the gun. The target includes a frame fronted by a simulated fence on top of which a plurality of objects, such as bottles, tin cans, and the like may be placed. A target impeller is provided on the frame in proximity to each of the objects so that, when actuated, the impeller will cause physical movement of the associated target knocking it off of the frame. The target impellers are actuated by a control mechanism, as a photo transistor therein senses the proper alignment of the light beam from the gun through one of a plurality of apertures located on the frame below each of the objects.